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Pathology image dyeing component adjusting method

A pathological image and adjustment method technology, applied in the field of pathological image dyeing component adjustment, can solve the problem of inability to separate different dye components and the like

Active Publication Date: 2018-02-16
BEIHANG UNIV
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  • Claims
  • Application Information

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Problems solved by technology

[0005] The purpose of the present invention is to provide a method for adjusting the dyeing components of pathological images, so as to solve the problem that the existing image processing technology cannot separate the components of different dyes in pathological images and realize the independent adjustment of different dyes in pathological images

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  • Pathology image dyeing component adjusting method

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Embodiment 1

[0061] A method for adjusting the staining components of pathological images, the specific process is as follows figure 2 As shown, including the following steps:

[0062] 1. Collect pathological sections

[0063] The pathological image is input into the computer through the pathological slice scanning device, and the image is represented in the RGB color space. The values ​​of the R, G, and B channels with pixel coordinates (x, y) are expressed as:

[0064] I(x,y)=[I r (x,y),I g (x,y),I b (x,y)] (3)

[0065] Where I r (x,y), I g (x,y), I b (x, y) respectively represent the values ​​of the three color channels of red, green and blue, and I c (x,y)∈[0,1], c=r,g,b.

[0066] 2. Saturation and brightness correction

[0067] During pathological image scanning, poor lighting conditions will result in poor image saturation and brightness. Therefore, it is necessary to correct the brightness and saturation of pathological images. The background area of ​​the pathological section (the area wit...

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Abstract

The invention discloses a pathology image dyeing component adjusting method. The pathology image dyeing component adjusting method firstly performing correction on the brightness and the saturation ofthe acquired pathology slices in the tone, saturation and brightness (HSV) space, can implement the algorithm of adjusting the content of the single dyeing component, can achieve the effect of independent adjusting of different coloring agents in the pathology image, and can effectively completes the task of dyeing separation and can assist diagnosis of a pathology doctor by performing correctionof the saturation and the brightness of the pathology slices, dyeing component separation, dyeing component adjusting and dyeing component synthesis on the saturation and the brightness of the corrected pathology slices.

Description

Technical field [0001] The invention relates to the field of digital image processing, and in particular to a method for adjusting the staining components of pathological images. Background technique [0002] Digital pathological images are high-resolution digital images obtained by scanning and collecting pathological slices through automatic microscopes or optical magnification systems, which have been widely used in pathological clinical diagnosis. The color of pathological sections is obtained by staining with stains, and the most commonly used staining method is hematoxylin-eosin (H-E) staining. However, human factors such as manual operation methods and differences in the ratio of staining agents during the staining process will cause differences in the staining quality of pathological slices. At the same time, the differences in the lighting environment during the scanning of the slices also cause the brightness of the collected digital pathological images. There is a big...

Claims

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Application Information

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IPC IPC(8): G06T7/90G06T5/00
CPCG06T7/90G06T2207/10056G06T2207/30096G06T5/90
Inventor 姜志国郑钰山张浩鹏谢凤英麻义兵
Owner BEIHANG UNIV