Method and kit for prognosis and guiding treatment of patients with laryngeal papilloma

A kit, HLA-DRB1 technology, applied in biochemical equipment and methods, microbial measurement/testing, DNA/RNA fragments, etc., can solve difficult problems and achieve simple operation, great application value, and low cost Effect
CN107828889AActive Publication Date: 2018-03-23BEIJING CHILDRENS HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
BEIJING CHILDRENS HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
Publication Date
2018-03-23

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Abstract

The invention relates to a gene detection method and kit capable of being used for clinical detection. The method is aimed at HLA-DRB1*03 low-resolution gene and can realize accurate, rapid, simple and inexpensive detection, and can be used for providing important information for treatment and prognosis of clinically relevant diseases such as recurrent laryngeal papilloma and the like.
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Description

technical field

[0001] The invention belongs to the field of gene diagnosis, and relates to a gene detection method and kit, as well as the application in clinical related diseases. technical background

[0002] Recurrent respiratory papilloma (RRP) is the most common benign tumor of the laryngeal epithelial tissue, and the main pathogens are human papillomavirus 6 and 11 subtypes. Repeated resection is the main treatment for this disease, but it cannot prevent recurrence. During the active stage of the disease, most patients may need to undergo an operation every 2-3 months, and some children may even undergo hundreds of operations in their lifetime, which brings a heavy burden to the patients and their families. In addition, the frequent recurrence of RRP increases the possibility of spreading the lesions to the lower respiratory tract, which in turn makes the disease more aggressive.

[0003] At present, there is no effective cure for RRP, but a variety of drugs have be...

Claims

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