Nose drop for treating allergic rhinitis and preparation method thereof

A technology for allergic rhinitis and nasal drops, which is applied in the field of medicine to achieve the effect of small size, simple preparation process and high safety

Inactive Publication Date: 2018-05-01
河南明珍方医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Up to now, there is still a lack of an ideal treatment method

Method used

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  • Nose drop for treating allergic rhinitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A nasal drop for treating allergic rhinitis is prepared from the following raw materials in parts by weight: 1 part of volatile oil of Pseudomonas sinensis, 2 parts of volatile oil of peppermint, 100 parts of sesame oil, and 0.05 part of paraben.

[0023] The method for preparing the described nasal drops for the treatment of allergic rhinitis comprises the following steps:

[0024] (1) Respectively take an appropriate amount of Xinyi and peppermint, add 5 times the weight of water, heat in a water bath at 100 ° C for 120 minutes, heat and extract 3 times, and collect Xinyi volatile oil and peppermint volatile oil with a volatile oil extractor; (2) Take sesame oil in proportion, Then add the volatile oil of Pseudomonas sinensis, volatile oil of peppermint and paraben obtained in step (1) into the sesame oil, and stir evenly;

[0025] (3) Distribute the material obtained in step (2), 5ml / bottle.

Embodiment 2

[0027] A nasal drop for treating allergic rhinitis, which is prepared from the following raw materials in parts by weight: 5 parts of volatile oil of Xinyi, 5 parts of volatile oil of peppermint, 150 parts of sesame oil, and 0.12 part of paraben.

[0028] The method for preparing the described nasal drops for the treatment of allergic rhinitis comprises the following steps:

[0029] (1) Respectively take an appropriate amount of Xinyi and peppermint, add 10 times the weight of water, heat in a water bath at 120 ° C for 30 minutes, heat and extract 3 times, and use a volatile oil extractor to collect Xinyi volatile oil and peppermint volatile oil respectively; (2) Take sesame oil in proportion, Then add the volatile oil of Pseudomonas sinensis, volatile oil of peppermint and paraben obtained in step (1) into the sesame oil, and stir evenly;

[0030] (3) Distribute the material obtained in step (2), 5ml / bottle.

Embodiment 3

[0032] A nasal drop for treating allergic rhinitis, which is prepared from the following raw materials in parts by weight: 2 parts of volatile oil of Pseudomonas sinensis, 3 parts of volatile oil of peppermint, 100 parts of sesame oil, and 0.06 part of paraben.

[0033] The method for preparing the described nasal drops for the treatment of allergic rhinitis comprises the following steps:

[0034] (1) Respectively take an appropriate amount of Xinyi and peppermint, add 15 times the weight of water, heat in a water bath at 110 ° C for 50 minutes, heat and extract 3 times, and collect Xinyi volatile oil and peppermint volatile oil with a volatile oil extractor; (2) Take sesame oil in proportion, Then add the volatile oil of Pseudomonas sinensis, volatile oil of peppermint and paraben obtained in step (1) into the sesame oil, and stir evenly;

[0035] (3) Distribute the material obtained in step (2), 5ml / bottle.

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PUM

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Abstract

The invention discloses a nose drop for treating allergic rhinitis and a preparation method thereof. The nose drop is prepared from the following raw materials in parts by weight: 1-5 parts of magnolia flower volatile oil, 2-5 parts of herba menthae volatile oil, 100-150 parts of sesame oil and 0.05-0.12 part of nipagin. The preparation method of the nose drop comprises the following steps: respectively taking a proper amount of flos magnoliae and herba menthae, adding water, performing heating, and respectively collecting the flos magnoliae volatile oil and the herba menthae volatile oil by using a volatile oil extractor; proportionally taking the sesame oil, then adding the obtained flos magnoliae volatile oil, the obtained herba menthae volatile oil and nipagin into the sesame oil, andperforming uniform stirring; and sub-packaging 5ml of the obtained substance in each bottle. The nose drop for treating allergic rhinitis is prepared from the volatile oil extracted from traditional Chinese medicine flos magnoliae and herba menthae; and the nose drop is small in volume, simple in preparation process, suitable for industrial mass production, fast in taking effect, convenient to use, high in safety and free from toxic and side effects, and provides more medication options for patients and especially out-of-hospital patients who suffer from allergic rhinitis and cannot orally take medicines.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a nasal drop for treating allergic rhinitis and a preparation method thereof. Background technique [0002] With the change of the global environment and climate, diseases of the respiratory system continue to rise. Rhinitis is an inflammatory disease of the nasal cavity. It is an inflammation of the nasal mucosa caused by viruses, bacteria, allergens, various physical and chemical factors and some systemic diseases. A common clinical disease, frequently-occurring disease. Common rhinitis includes acute and chronic rhinitis, atrophic rhinitis, sinusitis, allergic rhinitis, etc. Because there are many types of rhinitis, there are also many clinical manifestations of rhinitis, such as nasal itching, nasal congestion, excessive nasal discharge, decreased sense of smell, headache and dizziness, and most people are accompanied by loss of appetite, easy fatigue, memory lo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/575A61P11/02A61P37/08
CPCA61K36/575A61K9/0043A61K36/534A61K47/44A61K2236/331A61K2236/39A61K2300/00
Inventor 司会贞
Owner 河南明珍方医药科技有限公司
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