Oral traditional Chinese medicine film agent and method for preparing same

A technology of film preparation and traditional Chinese medicine, which is applied in the direction of medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of treatment effects, poor local adhesion, inconvenient use, etc., to improve drug utilization, Fast-acting, fast-dissolving effect

Inactive Publication Date: 2018-05-15
青岛恒新辉瑞工业技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The clinical curative effect of single-use oral medicine is not good. In the past, the commonly used dosage forms include powder, glycerin, ointment, etc. Although they have a certain effect o

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0025] Example 1:

[0026] Embodiment 1 of the present invention provides a traditional Chinese medicine film for oral use, which in parts by weight mainly includes 5 parts of raw materials and 30 parts of auxiliary materials.

[0027] In parts by weight, the APIs include 2 parts of Baiji, 1 part of Burnet, 0.15 parts of artificial bezoar, 1.5 parts of catechu, 2 parts of coptis, 0.5 parts of borneol, 0.5 parts of lychee grass, 1 part of Angelica dahurica, 2 parts of forsythia , 0.5 part of pine pollen, 2 parts of Rehmannia glutinosa, 0.5 part of ash leaves.

[0028] Excipients include polyvinyl alcohol, sodium carboxymethyl cellulose, glycerin, and Tween-80.

[0029] In addition, the present embodiment also provides a traditional Chinese medicine film for oral cavity and a preparation method thereof, comprising the following steps:

[0030] (1) Membrane preparation:

[0031] a. Weigh 15 parts of polyvinyl alcohol, add distilled water with a weight ratio of 1:1, heat it to ...

Example Embodiment

[0037] Example 2:

[0038] Embodiment 2 of the present invention provides a traditional Chinese medicine film for oral cavity, which mainly includes the following raw materials, in parts by weight: 70 parts of raw materials and 100 parts of auxiliary materials.

[0039] In parts by weight, the raw materials include 10 parts of Baiji, 7 parts of Burnet, 0.35 parts of artificial bezoar, 5 parts of catechu, 10 parts of Coptis chinensis, 3 parts of borneol, 5 parts of lychee grass, 7 parts of Angelica dahurica, 8 parts of Forsythia , 1.5 parts of pine pollen, 8 parts of Rehmannia glutinosa, 2 parts of ash leaves.

[0040] Excipients include polyvinyl alcohol, sodium carboxymethyl cellulose, glycerin, and Tween-80.

[0041] In addition, the present embodiment provides a traditional Chinese medicine film for oral cavity and a preparation method thereof, comprising the following steps:

[0042] (1) Membrane preparation:

[0043] a. Weigh 40 parts of polyvinyl alcohol, add distille...

Example Embodiment

[0049] Example 3:

[0050] Embodiment 3 of the present invention provides a traditional Chinese medicine film for oral use, which mainly includes the following raw materials, in parts by weight: 37 parts of raw materials and 65 parts of auxiliary materials.

[0051] In parts by weight, the APIs include 6 parts of Baiji, 4 parts of Burnet, 0.25 parts of artificial bezoar, 3.2 parts of catechu, 6 parts of coptis, 1.7 parts of borneol, 2.7 parts of lychee, 4 parts of angelica, and 5 parts of forsythia , 1 part of pine pollen, 5 parts of Rehmannia glutinosa, 1.25 parts of ash leaves.

[0052] Excipients include polyvinyl alcohol, sodium carboxymethyl cellulose, glycerin, and Tween-80.

[0053] In addition, the present embodiment provides a traditional Chinese medicine film for oral cavity and a preparation method thereof, comprising the following steps:

[0054] (1) Membrane preparation:

[0055] a. Weigh 27 parts of polyvinyl alcohol, add distilled water with a weight ratio of...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine preparation, and particularly discloses an oral traditional Chinese medicine film agent and a method for preparing the same. The oral traditional Chinese medicine film agent mainly comprises, by weight, 5-70 parts of raw materials and 30-100 parts of excipients. The oral traditional Chinese medicine film agent prepared bythe aid of the method is a square laminar film with the area of 1 cm<2>. The oral traditional Chinese medicine film agent and the method have the advantages that the oral traditional Chinese medicinefilm agent can be attached to the surfaces of mucosas, accordingly, effects of protecting the mucosas can be realized, site-specific delivery can be carried out on medicines, and curative effects canbe improved.

Description

field of invention [0001] The invention belongs to the technical field of preparation of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine film for oral cavity and a preparation method thereof. Background technique [0002] Film preparations refer to film-like internal and external preparations made by dissolving or suspending drugs or medicinal material extracts in suitable synthetic or natural film-forming materials. According to different film materials and drug properties, as well as clinical drug requirements, various films can be made into quick-acting drug films or quantitative sustained-release drug films. [0003] Oral ulcer is a common disease in oral mucosal diseases, and its pathogenesis is often related to viral infectious diseases or related to immune dysfunction. Due to the complex etiology, clinically, symptomatic treatment and topical medication are the main treatment methods. The curative effect of oral medicine al...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/70A61K47/38A61P1/02A61K35/413A61K31/045
CPCA61K36/898A61K9/006A61K31/045A61K35/413A61K36/15A61K36/232A61K36/48A61K36/537A61K36/63A61K36/634A61K36/718A61K36/739A61K36/804A61K47/38A61K2300/00
Inventor 张建华
Owner 青岛恒新辉瑞工业技术有限公司
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