The invention provides compound herbal antibacterial liquid as well as a preparation process and application thereof. The compound herbal antibacterial liquid comprises the following raw materials: a medicinal plant leachate, sesame oil, borneol, peppermint oil, chlorhexidine acetate, coptis chinensis, scutellaria baicalensis, golden cypress, sanguisorba officinalis, rheum officinale, catechu and peppermint oil. The preparation process comprises the following steps: adding the coptis chinensis, the scutellaria baicalensis, the golden cypress, the sanguisorba officinalis, the rheum officinale and the catechu which are crushed into the peppermint oil, performing stirring, performing dipping and performing extracting for one month to obtain the medicinal plant leachate; taking out small medicine bags, adding the sesame oil, the borneol and the chlorhexidine acetate, performing uniform stirring, and finally performing filling and packaging. The compound herbal antibacterial liquid is an external antibacterial liquid with complete functions, can be at least used for treating scalp tinea, scald, mosquito bite, knife injury, fall injury, carbuncle, surgical scars and acne, is high in medicine availability, is not limited by age, gender and race, and is safe and reliable. Particularly, the compound herbal antibacterial liquid i has the advantages of quick detoxification and detumescence, quick tissue regeneration and close-up, quick pus extraction and poison drawing, quick incrustation and pain relief, quick astringency and hemostasis, and quick insect killing and itching relieving.