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Pharmaceutical composition with freckle removing function and preparation method thereof

A composition and functional technology, which is applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of affecting physical and mental health, unsafe use, and large side effects, so as to reduce melanin, increase melanin, The effect of enhancing stability

Inactive Publication Date: 2018-07-24
武汉名实生物医药科技有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the common products for removing pigmented spots often add hydroquinone, which has large side effects, poor product stability, and cannot be used for a long time. Some products add fruit acid and other cuticle exfoliating agents to achieve the effect of removing spots by exfoliating the cuticle layer by layer. Purpose, although the effect is good, but it is not safe to use, and the side effects are large. What's more, heavy metals harmful to the body are added to the product to achieve the purpose of rapid freckle removal, which seriously affects people's physical and mental health; there are also some products Although some safe freckle-removing ingredients are used, such as vitamin C, arbutin, tocopherol, etc., most of them have no obvious effect or slow effect, and the safety and sequelae are still difficult to predict.

Method used

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  • Pharmaceutical composition with freckle removing function and preparation method thereof
  • Pharmaceutical composition with freckle removing function and preparation method thereof
  • Pharmaceutical composition with freckle removing function and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A pharmaceutical composition with the function of removing freckles, which consists of the following components:

[0022] Magnesium Ascorbyl Phosphate 0.9g

[0023] Phenylethylresorcinol 0.1g

[0024] Traditional Chinese Medicine Extract Concentrate 0.1g

[0025] The Chinese medicine extraction concentrate is prepared as follows: take 5g salvia miltiorrhiza, 5g poria cocos, 5g licorice, 5g wolfberry, 5g safflower, 5g astragalus, 5g cortex moutan, 5g ginseng, 5g notoginseng and 5g gastrodia elata, add 400g water, soak for 60 minutes, then decoct and extract for 1 hour, filter the extract, add 300g water to the medicinal residues for the second decoction and extract, the extraction time is 1 hour, filter the extract, and combine the first and The second extracts were combined and concentrated to a relative density of 1.08 at 60°C.

[0026] The preparation method of the pharmaceutical composition: take 1g of carbomer, dissolve it with 100g of water, and make a gel matri...

Embodiment 2

[0028] A pharmaceutical composition with the function of removing freckles, which consists of the following components:

[0029] Magnesium Ascorbyl Phosphate 0.5g

[0030] Phenylethylresorcinol 1g

[0031] Chinese Herbal Extract Concentrate 2g

[0032] The preparation method of the Chinese medicine extract concentrate is the same as in Example 1.

[0033] Mix the above magnesium ascorbyl phosphate, phenylethyl resorcinol, traditional Chinese medicine extract concentrate, 100ml of water, and 0.5g of ethyl p-hydroxybenzoate, heat to 75-85°C, stir evenly, and obtain the water phase; another 8g Stearyl alcohol, 5g self-emulsifying glyceryl monostearate, 1g squalane, 1g caprylic / capric triglyceride, 0.5g silicone oil, 0.5g ceteareth-25, 0.2g cetearyl Alcohol-6, after mixing, heat to 75-85°C, stir evenly to obtain oil phase; mix water phase and oil phase, emulsify at 75-85°C for 10 minutes, cool, fill to make cream .

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Abstract

The invention discloses a pharmaceutical composition with a freckle removing function. The pharmaceutical composition is prepared from the following components in parts by weight: 0.1 to 3 parts of magnesium ascorbyl phosphate, 0.05 to 2 parts of phenylethyl resorcinol and 0.05 to 5 parts of traditional Chinese medicine extracting solution. The invention further discloses a preparation method of the composition. The composition disclosed by the invention has a bidirectional regulation effect, can be used for alleviating melanin pigmentation and also can be used for increasing melanin at positions without the melanin, so that the skin color is unified; meanwhile, the pharmaceutical composition also has the advantages of small side effect, good stability and the like.

Description

technical field [0001] The invention belongs to the field of medicine or cosmetics, and in particular relates to a pharmaceutical composition with the function of removing freckles and a preparation method thereof. Background technique [0002] Pigmented spots are spots or plaques caused by the uneven distribution of melanin secreted by melanocytes in the body. They are more common on the face and seriously affect an individual's external image. At present, common products for removing pigmented spots often add hydroquinone, which has large side effects, poor product stability, and cannot be used for a long time. Some products add fruit acid and other cuticle exfoliating agents to achieve the effect of removing spots by exfoliating the cuticle layer by layer. Purpose, although the effect is good, but it is not safe to use, and the side effects are large. What's more, heavy metals harmful to the body are added to the product to achieve the purpose of rapid freckle removal, wh...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P17/00A61K31/661A61K31/05
CPCA61K31/05A61K31/661A61K36/076A61K36/258A61K36/286A61K36/481A61K36/484A61K36/537A61K36/65A61K36/71A61K36/815A61K36/8988A61K2236/331A61K2236/39A61K2300/00
Inventor 不公告发明人
Owner 武汉名实生物医药科技有限责任公司
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