Method for preparing specnuezhenide from glossy privet fruit

Abstract

The invention relates to the technical field of traditional Chinese medicine, in particular to a method for preparing specnuezhenide from glossy privet fruits. According to the method, the glossy privet fruits are used as raw materials; backflow extraction is performed through hydrous ethanol; extraction liquid is subjected to filtering concentration and is then purified twice by macroporous resin; then, crystallization is performed through ethanol; a specnuezhenide compound is prepared; the purity reaches 98.2 percent or higher. The method has the advantages that the raw materials are rich and can be easily obtained; the process is simple; the implementation is easy; the operation is simple and convenient; the efficiency is high; the environment is protected; the production cots is lower;the method is applicable to industrial production.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a method for preparing privet privet from privet fruit. Background technique [0002] Ligustrum lucidum is the dry and ripe fruit of Oleaceae plant Ligubtrum lucidum ait., which has the effects of nourishing liver and kidney, improving eyesight and black hair. Studies in recent years have shown that iridoid glycosides are one of the main active ingredients of Ligustrum lucidum, and privet privet is a higher content of iridoid glycosides in Ligustrum lucidum, which has anti-osteoporosis , anti-oxidation, liver protection and other pharmacological effects. In the past, the main steps for isolating privet privet from Ligustrum lucidum were as follows: Ligustrum lucidum was extracted with 70% ethanol under reflux, the extract was recovered from ethanol and then suspended in water, followed by petroleum ether, chloroform, ethyl acetate, n-butanol, respectively. ...

AI Technical Summary

Problems solved by technology

[0003] The organic solvents used in the above-mentioned preparation method include methanol, petroleum ether, ethyl acetate, chloroform, and n-butanol. These reagents are highly toxic, costly, and likely to cause environmental pollution, and the product is prone to residual organic solvents, thereby affecting the product. security

In addition, the reverse silica gel, gel, and medium-pressure preparations used in the above preparation methods are expensive, and the steps are cumbersome and time-consuming.

The above method is difficult to be used in industrialized production

Images