Application of LED-red light with wavelength of 610-650 nm in relieving symptoms of lumbar muscle strain

A lumbar muscle strain and red light technology, applied in the field of photomedicine, can solve problems such as difficult to cure lumbar muscle strain, affect the quality of life of patients, and easy to relapse, so as to relieve the symptoms of lumbar muscle strain, simple and easy clinical application, and improve life quality effect

Inactive Publication Date: 2018-08-14
HARBIN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although lumbar muscle strain does not affect people's normal life, it is difficult to cure, easy to relapse, long-term and often leads to long-term drug pain, which seriously affects the quality of life of patients
At present, the methods for treating lumbar muscle strain mainly include traditional Chinese medicine and western medicine, both of which are directly aimed at treating lumbar muscle strain. at the same time, the use of drugs is very easy to produce toxic side effects, so we want to treat lumbar muscle strain from the perspective of treating or slowing down osteoporosis

Method used

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  • Application of LED-red light with wavelength of 610-650 nm in relieving symptoms of lumbar muscle strain
  • Application of LED-red light with wavelength of 610-650 nm in relieving symptoms of lumbar muscle strain
  • Application of LED-red light with wavelength of 610-650 nm in relieving symptoms of lumbar muscle strain

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1: Relief of 610-650nm LED-red light irradiation on the symptoms of low back pain caused by lumbar muscle strain

[0026] 1. Preparation of belt

[0027] Phototherapy belt: Arrange the light strips with red light with a wavelength of 610-650nm neatly and sew them between the nylon cloth and the black filter at the waist support of the belt for health care, and the total light intensity is 10mW / cm 2 . The tail of the power supply is exposed outside the belt, and it will light up when it is connected to the socket. The magic glue is sewn on the closure of the belt, and the size of the belt can be adjusted and glued according to the size of the waist. The structure of the belt is as figure 1 (before power on) and figure 2 (after power-on).

[0028] Heat belt: replace the light strip with 610-650nm wavelength red light in the phototherapy belt with a heating device, which generates heat equivalent to that produced by the light strip.

[0029] 2. Experimental ...

Embodiment 2

[0040] Example 2: Effect of 610-650nm LED-red light irradiation on osteogenic differentiation of mouse bone marrow mesenchymal stem cells

[0041] 1. Experimental method

[0042] 1.1 Alizarin red staining was used to detect the osteogenic differentiation ability of mouse bone marrow mesenchymal stem cells

[0043] The back skin of the mouse was taken for in vitro culture, and the skin was irradiated with 610-650nm LED-red light for 30 minutes, and the light intensity was 20mW / cm 2 (The distance is 19.5cm). Collect the culture medium after light irradiation, call this culture medium as the conditioned medium, add the conditioned medium to the mouse bone marrow mesenchymal stem cells cultured in vitro, induce the mouse bone marrow mesenchymal stem cells to differentiate into osteoblasts, and after 14 days Alizarin red staining was used to detect the osteogenic differentiation ability of mouse bone marrow mesenchymal stem cells.

[0044] 1.2 Experimental group design

[0045]...

Embodiment 3

[0050] Embodiment 3: 610-650nm LED-red light irradiation increases the bone mass of C57BL / 6 mice

[0051] 1. Experimental method

[0052] 1.1 MicroCT detection of mouse femur bone mass

[0053] Apply 610-650nm LED-red light or natural light to irradiate 8-week-old male C57BL / 6 mice for 2 hours a day, with a light intensity of 50mW / cm 2 (The distance is 18cm). After 6 months, the mouse femurs were taken out for MicroCT scanning.

[0054] 1.2 Experimental group design

[0055] The experiment was divided into control group and experimental group according to natural light irradiation and red light irradiation.

[0056] 1.3 Experimental testing items

[0057] mouse femur bone mass

[0058] 2. Observation results

[0059] The result is as Figure 4 As shown, the results of MicroCT showed that compared with the control group, the bone mass of mice in the experimental group irradiated with LED-red light increased, indicating that 610-650nm LED-red light irradiation can increa...

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Abstract

The invention discloses application of LED-red light with a wavelength of 610-650 nm in relieving symptoms of lumbar muscle strain. In addition, the invention also puts forward application of LED-redlight source with a wavelength of 610-650nm in manufacturing instruments for promoting differentiation of bone marrow mesenchymal stem cells into osteoblasts and manufacturing instruments for increasing bone mass. The application disclosed in the invention is simple and easy to implement in clinic application and low in medical treatment cost. Symptoms of lumbar muscle strain in patients can be effectively alleviated, quality of life of patients can be improved, economic burdens of patients can be reduced, a series of side effects caused by drug treatment can be alleviated to some extent, discomfort caused by conventional physical therapies to patients is alleviated to some extent, and the application disclosed in the present invention provides a new technical means for the treatment of lumbar muscle strain.

Description

technical field [0001] The invention relates to a new application of LED-red light with a wavelength of 610-650nm, in particular to a new application of LED-red light with a wavelength of 610-650nm in treating lumbar muscle strain. The invention belongs to the technical field of photomedicine. Background technique [0002] Lumbar muscle strain is a general term for muscle and ligament injuries of "low back fascial pain syndrome". Middle-aged and elderly people are often accompanied by osteoporosis when back pain occurs. The most common symptom is back pain, which accounts for 70% to 80% of pain patients. Middle-aged and elderly people and patients with osteoporosis often suffer from vertebral body compression deformation, muscle fatigue and even spasm, resulting in pain. Therefore, the pain caused by lumbar muscle strain can be relieved by treating osteoporosis or slowing down the occurrence and development of osteoporosis. [0003] Although lumbar muscle strain does not ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/06
CPCA61N5/0625A61N2005/0645A61N2005/0651A61N2005/0662
Inventor 杨磊蔡本志袁野孙毅杨帆
Owner HARBIN MEDICAL UNIVERSITY
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