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Systems and methods for thermal cycler heating mantles

A thermal cycler, heating mantle technology, applied in chemical instruments and methods, heating or cooling equipment, instruments, etc., can solve problems such as expensive

Active Publication Date: 2021-08-10
LIFE TECH CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, such methods are expensive to implement

Method used

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  • Systems and methods for thermal cycler heating mantles
  • Systems and methods for thermal cycler heating mantles
  • Systems and methods for thermal cycler heating mantles

Examples

Experimental program
Comparison scheme
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Embodiment Construction

[0018] refer to Figures 1 to 4 , shows a thermal cycler system 10 constructed in accordance with an illustrative embodiment of the invention. Thermal cycler system 10 includes an outer housing 12 and a sample block 14 configured to receive a sample holder 16 . The sample block 14 comprises a plurality of cavities 18 and is configured to house correspondingly shaped sample holders 16 containing a plurality of biological or biochemical samples in a plurality of wells 20, such as Figure 8 best shown in . The thermal cycler system 10 further comprises a pressure rod 24 operatively coupled to Figure 5A Shown in ) and the heating mantle or platen 22 of the cover 26. The heating mantle 22 is configured to provide a downward force to the sample holder 16 . The downward force provides vertical compression between the sample holder 16, sample block 14, and other components of the thermal block assembly (not shown), which improves thermal contact between the sample block 14 and sa...

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PUM

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Abstract

A thermal cycler system for use with a sample holder configured to receive a plurality of samples comprising: a sample block configured to receive the sample holder; direction of the sample block from an open position to a closed position; a heating shield operatively coupled to the cover and configured to move toward the sample block when the sample holder is received by the sample block Directionally moving from a raised position to a first lowered position, in which the heating shield contacts the sample holder; and a drive assembly, which includes a motion guide, the motion guide configured to move in a direction towards the sample block from a first position in which the cover is in the open position and the heating mantle is in the raised position to a second position , the cover is in the closed position in the second position.

Description

technical field [0001] The present invention generally relates to thermal cycler systems and methods of using thermal cycler systems. Background technique [0002] Testing of biological or chemical samples typically requires a device for repeatedly subjecting samples to a series of temperature cycles. One example of an instrument that may be utilized for preparing, viewing, testing and / or analyzing arrays of biological samples is a thermocycler or thermocycling device, such as an endpoint polymerase chain reaction (PCR) instrument or a quantitative or real-time PCR instrument. Such means are used to generate specific temperature cycles, ie to set a predetermined temperature in the reaction vessel to be maintained for a predetermined time interval. [0003] In general, it is desirable to increase the efficiency and output of the PCR process. The advantages of automated biological sample processing instruments allow for faster and more efficient sample analysis. However, su...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01L7/00G01N35/02
CPCB01L7/52G01N35/026B01L2200/143B01L2300/045B01L2300/046B01L2300/0609B01L2300/0663B01L2300/1827B01L2200/025B01L2300/041B01L2300/18
Inventor 陈泽棋罗戊耿利秀芸巫冠文
Owner LIFE TECH CORP