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Medical hemostasis antibacterial dressing and preparation method thereof

A hemostatic antibacterial and raw material technology, applied in medical science, absorbent pads, bandages, etc., can solve the problems of not being able to keep the wound moist, delay wound healing, and damage granulation tissue, so as to speed up skin healing, promote healing and repair, and promote The effect of tissue repair

Pending Publication Date: 2018-09-04
薛春玲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional dressings also have obvious disadvantages, such as not keeping the wound moist and delaying wound healing; wound granulation tissue is easy to grow into the mesh of the dressing, and it is easy to adhere to the wound when the dressing is changed, damaging the new granulation tissue and causing pain; the dressing penetrates Poor posterior barrier effect, easy to cause exogenous infection, poor hemostatic effect

Method used

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  • Medical hemostasis antibacterial dressing and preparation method thereof
  • Medical hemostasis antibacterial dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A medical hemostatic antibacterial dressing is prepared from the following raw materials in parts by weight: 70 parts of polyglutamic acid-pullulan polysaccharide crosslinked polymer, 30 parts of collagen, 15 parts of bamboo vinegar powder, 15 parts of glycolic acid, 8 parts of garlic polysaccharide, 10 parts of hyaluronic acid, 55 parts of purified water.

[0026] As mentioned above, the polyglutamic acid-pullulan polysaccharide cross-linked polymer is prepared by the following method: adding the pullulan polysaccharide solution to the polyglutamic acid solution, stirring and reacting at 35°C for 1.2h, without Precipitate the mixed solution with water and ethanol, collect the precipitate by vacuum filtration, dissolve the precipitate with deionized water, place it in a dialysis bag for dialysis for 1 hour, and freeze-dry the dialysis retentate to obtain a polyglutamic acid-pullulan cross-linked polymer.

[0027] Said, the mass ratio of polyglutamic acid solution and pu...

Embodiment 2

[0037] A medical hemostatic and antibacterial dressing is prepared from the following raw materials in parts by weight: 60 parts of polyglutamic acid-pullulan polysaccharide crosslinked polymer, 35 parts of collagen, 13 parts of bamboo vinegar powder, 18 parts of glycolic acid, 6 parts of garlic polysaccharide, 15 parts of hyaluronic acid, 50 parts of purified water.

[0038] As mentioned above, the polyglutamic acid-pullulan polysaccharide cross-linked polymer is prepared by the following method: adding the pullulan polysaccharide solution to the polyglutamic acid solution, stirring and reacting at 40°C for 1.1h, without Precipitate the mixed solution with water and ethanol, collect the precipitate by vacuum filtration, dissolve the precipitate with deionized water, place it in a dialysis bag for dialysis for 1.5 hours, and freeze-dry the dialysis retentate to obtain polyglutamic acid-pullulan cross-linked polymer .

[0039] Said, the mass ratio of polyglutamic acid solution...

Embodiment 3

[0049] A medical hemostatic and antibacterial dressing is prepared from the following raw materials in parts by weight: 80 parts of polyglutamic acid-pullulan polysaccharide crosslinked polymer, 25 parts of collagen, 17 parts of bamboo vinegar powder, 12 parts of glycolic acid, 10 parts of garlic polysaccharide, 5 parts of hyaluronic acid, 60 parts of purified water.

[0050] As mentioned above, the polyglutamic acid-pullulan polysaccharide cross-linked polymer is prepared by the following method: adding the pullulan polysaccharide solution to the polyglutamic acid solution, stirring and reacting at 30°C for 1.4h, without Precipitate the mixed solution with water and ethanol, collect the precipitate by vacuum filtration, dissolve the precipitate with deionized water, place it in a dialysis bag for dialysis for 0.5h, and freeze-dry the dialysis retentate to obtain polyglutamic acid-pullulan cross-linked polymer .

[0051] Said, the mass ratio of polyglutamic acid solution and ...

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Abstract

The invention discloses a medical hemostasis antibacterial dressing. The medical hemostasis antibacterial dressing is prepared from the raw materials in parts by weight: 60 to 80 parts of polyglutamicacid-Pulullan cross-linked polymer, 25 to 35 parts of collagen, 13 to 17 parts of bamboo vinegar powder, 12 to 18 parts of glycollic acid, 6 to 10 parts of garlic polysaccharide, 5 to 15 parts of hyaluronic acid, and 50 to 60 parts of pure water. The invention also discloses a preparation method of the medical hemostasis antibacterial dressing. The medical hemostasis antibacterial dressing of theinvention has excellent performance for covering wounds, helping the wound healing, efficiently stopping bleeding, preventing the bacterial invasion, promoting the tissue restoration and preventing the adhesion, can rapidly absorb the water in the blood when contacting the wound, can keeping the environment wet, and can effectively seal the bleeding wound.

Description

technical field [0001] The invention belongs to the field of medical dressings, in particular to a medical hemostatic and antibacterial dressing and a preparation method thereof. Background technique [0002] Blood is an opaque red liquid that flows in the heart and blood vessels, and its main components are plasma, red blood cells, white blood cells, and platelets. Plasma accounts for about 55% of blood and is a mixture of water, sugar, fat, protein, potassium and calcium salts. Blood cells make up the other 45% of the blood. Clinical medicine points out that if the human body does not take effective first aid measures due to acute bleeding, the patient will die within 6-20 minutes. If the blood loss of the human body exceeds 20% of the whole body's blood volume (about 800cc for adults), shock occurs; if the blood loss exceeds 40% of the whole body's blood volume (about 1600cc for adults), it is on the verge of death. According to statistics, the number of traumatic deat...

Claims

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Application Information

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IPC IPC(8): A61L15/26A61L15/28A61L15/32A61L15/42A61L15/44A61L15/46
CPCA61L15/26A61L15/28A61L15/325A61L15/425A61L15/44A61L15/46A61L2300/30A61L2300/404A61L2300/412C08L5/00C08L5/08C08L77/04
Inventor 薛春玲
Owner 薛春玲
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