Traditional Chinese medicine composition for improving intestinal flora distribution and application

A technology of intestinal flora and composition, which is applied in the direction of drug combination, plant/algae/fungus/moss components, pharmaceutical formulations, etc., can solve problems such as the decrease of intestinal flora diversity, and achieve the purpose of improving intestinal health and increasing intestinal health. Ratio, effect of promoting nutrient absorption and utilization

Inactive Publication Date: 2018-09-14
CHIATAI QINGCHUNBAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(3) Decreased diversity of intestinal flora

Method used

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  • Traditional Chinese medicine composition for improving intestinal flora distribution and application
  • Traditional Chinese medicine composition for improving intestinal flora distribution and application
  • Traditional Chinese medicine composition for improving intestinal flora distribution and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] 1. Traditional Chinese medicine composition formula: Rehmannia glutinosa 400g, Poria cocos 75g, asparagus 25g.

[0025] 2. Preparation method: Take rehmannia glutinosa, asparagus and poria cocos in the formula, add 10 times the mass of water and decoct 3 times, decoct for 2 hours for the first time, decoct for 1 hour for the second and third times respectively, and combine the decoctions, Filtrate, and concentrate the filtrate to a relative density of 1.30-1.40 (60° C.) to obtain about 250 g of extract, add 200 g of honey and mix to make a paste.

Embodiment 2

[0027] 1. The formula of traditional Chinese medicine composition: Rehmannia glutinosa 163g, Poria cocos 33g, Asparagus 10g, Digupi 12g, Ophiopogon japonicus 8g.

[0028] 2. Preparation method: Take raw rehmannia glutinosa, Ophiopogon japonicus, Radix Asparagus, Digupi, and Poria cocos in the formula, add 8 times the mass of water and decoct 3 times. The first decoction is 2 hours, and the second and third decoctions are respectively After 1 hour, the decoctions were combined, filtered, and the filtrate was concentrated to a relative density of 1.30-1.40 (60°C) to obtain about 112 g of extract, which was then dried and granulated with 80 g of starch to make granules.

Embodiment 3

[0030] 1. Traditional Chinese medicine formula: Rehmannia glutinosa 150g, red ginseng 55g, Poria cocos 33g, Radix Ophiopogon japonicus 9g, Asparagus 9g, Digupi 9g.

[0031] 2. Preparation method: Take raw rehmannia glutinosa, Ophiopogon japonicus, Radix Asparagus, Digupi, and Poria cocos in the formula, add 8 times the mass of water and decoct 3 times. The first decoction is 2 hours, and the second and third decoctions are respectively After 1 hour, the decoctions were combined, filtered, and the filtrate was concentrated to a relative density of 1.30-1.40 (60°C) to obtain 105 g of extract. Red ginseng is crushed into fine powder, dried and granulated with extract and 30-40g starch, compressed into tablets and coated to make tablets. It can also be made into capsules after being granulated, adding appropriate amount of auxiliary materials to the whole granules to fill the capsules.

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Abstract

The invention discloses a traditional Chinese medicine composition for improving intestinal flora distribution and application. The traditional Chinese medicine composition is prepared from, by mass,14-18 parts of radix rehmanniae recen, 2-4 parts of poria cocos and 1-2 parts of radix asparagi. By means of the composition and a preparation thereof, the ratio of thick-walled bacteria doors/bacteroid doors can be increased, the secretion of short chain fatty acid by intestines is promoted, and inflammation reaction is restrained. The thick-walled bacteria doors comprise various microorganisms beneficial for health, and the nutrient absorption and utilization can be promoted. The diversity of intestinal flora is an important index of the intestine health level and is closely related to the ageing of an organism. By means of the composition, the diversity of intestinal flora can be remarkably improved, the intestine health is enhanced, and the disease risk is reduced.

Description

(1) Technical field [0001] The invention relates to a traditional Chinese medicine composition for improving intestinal flora distribution and application thereof. (2) Background technology [0002] The human body is a very complex ecosystem. There are trillions of cells of microorganisms living inside and outside the human body, and more than 90% of the symbiotic microorganisms live in the human digestive tract, called "gut flora", which play an indispensable role in human health. The disorder of its structure is closely related to the occurrence and development of various chronic diseases. With the development and in-depth study of a large number of gut microbes, scientists have discovered that a series of human diseases, such as diabetes, obesity, rheumatoid, Parkinson's disease, cardiovascular and cerebrovascular diseases, and some mental diseases, are all related to gut microbes. Much progress has been made in the development of new microbial diagnostics, therapeutics...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8965A61K36/8968A61P1/00
CPCA61K36/076A61K36/258A61K36/804A61K36/815A61K36/8965A61K36/8968A61K2236/331A61K2236/39A61K2236/51A61P1/00A61K2300/00
Inventor 陈欢钱景刘雳刘程智瞿海斌程翼宇
Owner CHIATAI QINGCHUNBAO PHARMA
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