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Joint analgesic tincture and preparation method and application thereof

An analgesic tincture and joint technology, applied in non-central analgesics, anti-inflammatory agents, pharmaceutical formulations, etc., can solve problems such as joint deformities and movement disorders, affecting the quality of life of the sick, and inability to carry out thorough treatment, so as to reduce joint pain and reduce joint pain. The effect of swelling and pain, outstanding clinical efficacy, and good development prospects

Active Publication Date: 2018-09-25
范宏涛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A large number of lymphocytes, macrophages, and plasma cells may gather and infiltrate in the local joint tissues of inflammatory joint disease, which will cause swelling and pain in the local joints of the patient, and recurrent attacks will lead to joint deformity and movement disorders in the long run, and loss of labor force. , seriously affecting the quality of life of patients
So far, there is still no completely effective treatment method or drug, and it is impossible to perform a thorough treatment

Method used

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  • Joint analgesic tincture and preparation method and application thereof
  • Joint analgesic tincture and preparation method and application thereof
  • Joint analgesic tincture and preparation method and application thereof

Examples

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preparation example Construction

[0026] In addition, the present invention also provides a preparation method of the above joint pain relieving tincture, comprising the following steps:

[0027] S1: Mix Rhizoma Dianzhong and Achyranthes bidentata, and then soak them in an alcohol solution with a volume fraction of 25% to 35% for 6 to 8 days; filter after soaking, and the collected extract is the first composition; among them, Dianzhonglou The ratio of the total mass of Achyranthes bidentata and the volume of alcohol solution is 400g: (1400~1600)mL;

[0028] S2: Mix Polygonum cuspidatum and raw rhubarb, and then use alcohol solution with a volume fraction of 25% to 35% to soak for 6 to 8 days; filter after soaking, and the collected extract is the second composition; The ratio of the mass to the volume of the alcohol solution is 700g: (1400-1600)mL;

[0029] S3: Mix the first composition and the second composition uniformly at a volume ratio of 1: (0.9-1.1), let it stand for clarification, and then filter. Th...

Embodiment 1

[0032] This embodiment provides a joint pain relieving tincture, the raw material components include: 200g of Dianzhonglou, 200g of Achyranthes bidentata, 300g of Polygonum cuspidatum and 400g of raw rhubarb.

[0033] According to above-mentioned raw material, adopt preparation method provided by the invention, prepare joint pain relieving tincture:

[0034] S1: Mix 200g Dianzhonglou and 200g Achyranthes bidentata, soak in 1500mL alcohol solution with a volume fraction of 30% for 7 days; filter after soaking, and collect the leachate as the first composition;

[0035] S2: Mix 300g of Polygonum cuspidatum and 400g of raw rhubarb, and then use 1500mL of alcohol solution with a volume fraction of 30% to soak for 7 days; filter after soaking, and the collected extract is the second composition;

[0036] S3: Mix 1000mL of the first composition and 1000mL of the second composition evenly, let it stand for clarification, and then filter. The collected liquid is joint pain relief tinc...

Embodiment 2

[0038] This embodiment provides a joint pain relieving tincture, the raw materials of which include: 190g of Rhizoma Dianzhong, 210g of Achyranthes bidentata, 260g of Polygonum cuspidatum and 440g of raw rhubarb.

[0039] According to above-mentioned raw material, adopt preparation method provided by the invention, prepare joint pain relieving tincture:

[0040] S1: Mix 190g of Dianzhonglou and 210g of Achyranthes bidentata, and then soak in 1500mL of alcohol solution with a volume fraction of 30% for 7 days; filter after soaking, and the collected leachate is the first composition;

[0041]S2: Mix 260g of Polygonum cuspidatum and 440g of raw rhubarb, and then use 1500mL of alcohol solution with a volume fraction of 30% to soak for 7 days; filter after soaking, and the collected extract is the second composition;

[0042] S3: Mix 1000mL of the first composition and 1000mL of the second composition evenly, let it stand for clarification, and then filter. The collected liquid is...

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Abstract

The invention relates to a joint analgesic tincture and a preparation method and application thereof. The joint analgesic tincture comprises, by weight, 150-250 parts of rhizoma paridis yunnanensis, 180-210 parts of achyranthes root, 250-350 parts of polygonum cuspidatum and 360-440 parts of raw rheum officinale. The preparation method comprises mixing rhizoma paridis yunnanensis and achyranthes root, soaking the mixture in an alcohol solution, filtering the solution, collecting the leachate as a first composition, mixing polygonum cuspidatum and raw rheum officinale, soaking the mixture in analcoholic solution, filtering the solution, collecting the leachate as a second composition, uniformly mixing the first composition and the second composition, standing to clarify the mixture, filtering the mixture and collecting the liquid as the joint analgesic tincture. The joint analgesic tincture has obvious clinical effects on local treatment on inflammatory joint diseases and the effects comprise relieving joint swelling, reducing the number of tender joints, relieving joint pain and improving the patient's response to pain.

Description

technical field [0001] The invention relates to the technical field of medicine preparation, in particular to a tincture for relieving joint pain and its preparation method and application. Background technique [0002] Inflammatory joint diseases include a large group of rheumatic diseases with peripheral arthritis as the main manifestation, such as rheumatoid arthritis (RA), spondyloarthropathy (SpA) and related arthritis, crystal arthritis (gouty joint inflammation, etc.). A large number of lymphocytes, macrophages, and plasma cells may gather and infiltrate in the local joint tissues of inflammatory joint disease, which will cause swelling and pain in the local joints of the patient, and recurrent attacks will lead to joint deformity and movement disorders in the long run, and loss of labor force. , seriously affecting the quality of life of the sick. So far, there is still no completely effective treatment or medicine, and it is impossible to treat it thoroughly. The...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/08A61P19/02A61P19/06A61P29/00
CPCA61K9/0014A61K9/08A61K36/21A61K36/704A61K36/708A61K36/896A61K2236/333A61P19/02A61P19/06A61P29/00A61K2300/00
Inventor 范宏涛
Owner 范宏涛
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