Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Hydroxylamine hydrochloride synthesis method

A technology for the synthesis of hydroxylamine hydrochloride, which is applied in the fields of hydroxylamine, chemical instruments and methods, nitrogen compounds, etc., and can solve the problems of large amount of waste water, low yield, low purity, etc.

Active Publication Date: 2018-09-28
CHINA CATALYST HLDG CO LTD
View PDF5 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

To overcome the technical problems of large amount of waste water, long reaction cycle, low yield and low purity in the existing preparation method

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Hydroxylamine hydrochloride synthesis method
  • Hydroxylamine hydrochloride synthesis method
  • Hydroxylamine hydrochloride synthesis method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Put 100g (36.5%) hydrochloric acid and 141g pinacolone oxime into the reaction flask, raise the temperature to 70°C, react for 2 hours, cool and separate, and distill the water layer under reduced pressure. When solids precipitate in the flask, add 210g of ethanol to crystallize and filter to obtain Hydroxylamine hydrochloride, the results are shown in Table 1.

Embodiment 2

[0027] Put 100g (36.5%) hydrochloric acid and 141g pinacolone oxime into the reaction flask, raise the temperature to 75°C, react for 2 hours, cool and separate, and distill the water layer under reduced pressure. When solids precipitate in the flask, add 210g of ethanol to crystallize and filter to obtain Hydroxylamine hydrochloride, the results are shown in Table 1.

Embodiment 3

[0029] Put 100g (36.5%) hydrochloric acid and 141g pinacolone oxime into the reaction flask, raise the temperature to 70°C, react for 3 hours, cool and separate, and distill the water layer under reduced pressure. When solids precipitate in the flask, add 210g of ethanol to crystallize and filter to obtain Hydroxylamine hydrochloride, the results are shown in Table 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a hydroxylamine hydrochloride synthesis method which comprises the following steps: putting pinacolone oxime and a concentrated hydrochloric acid solution into a kettle in a mole ratio of 1.2-1.5 to 1, intensely stirring, heating to 70-80 DEG C, and carrying out hydrolysis; cooling, leaving to stand and layer, collecting an upper layer, namely pinacolone, and a lower layer,namely a hydroxylamine hydrochloride solution, carrying out vacuum distillation on a water layer, separating a white crystal in the kettle, adding ethanol, cooling, crystallizing, and filtering, so as to obtain hydroxylamine hydrochloride of high purity and high yield. By adopting the hydroxylamine hydrochloride synthesis method, side reactions in a hydrolysis process can be avoided, the purity of hydroxylamine hydrochloride can be improved, the yield of the hydroxylamine hydrochloride can be increased, in addition, the method has the characteristics of being simple in step, easy in raw material obtaining, small in wastewater amount, good in environmental-friendliness, and the like.

Description

Technical field [0001] The invention belongs to a method for synthesizing hydroxylamine salt, and relates to a method for synthesizing hydroxylamine hydrochloride. Background technique [0002] It is mainly used as a reducing agent and imaging agent, in organic synthesis for the preparation of oximes, and also as a raw material for the synthesis of anticancer drugs (hydroxyurea), sulfa drugs (sulfamethoxazole) and pesticides (metacarb). Used as a depolarizer in electroanalysis, as a short-term stop agent without coloring in the synthetic rubber industry, etc. The pharmaceutical industry is used as an intermediate of Trimoxazole. The synthetic dye industry is used for the preparation of isatin intermediates. Oil industry is used as antioxidant and antioxidant for fatty acid and soap. Analytical chemistry is used as a reducing agent for the analysis of formaldehyde, furfural, camphor and glucose. Depolarizer in electrochemical analysis. It is also used for the determination of...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C01B21/14
CPCC01B21/1409
Inventor 王庆吉王建青王蕊李进王炳春
Owner CHINA CATALYST HLDG CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com