Rhizoma bletillae extract and application thereof

A technology of extract and ethanol extract, which is applied in the field of white and extract and its application, can solve the problems of unstable preparation quality and unknown medicinal ingredients
CN108743801AInactive Publication Date: 2018-11-06ZHEJIANG CHINESE MEDICAL UNIVERSITY

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
ZHEJIANG CHINESE MEDICAL UNIVERSITY
Publication Date
2018-11-06
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a rhizoma bletillae extract and application thereof. The rhizoma bletillae extract is prepared by the following steps: carrying out backflow extraction on dried rhizoma bletillae powder with a 60-90% ethanol solution, filtering, and collecting filtrate so as to obtain a rhizoma bletillae alcohol extract; adsorbing the rhizoma bletillae extract with polyamide and a D101 macroporous resin in sequence, collecting a 35-45% ethanol eluant, and carrying out vacuum evaporation drying, thereby obtaining the rhizoma bletillae extract. In-vivo SD (Sprague Dawley) rat chronic bronchitis mode experiments show that rhizoma bletillae and an effective part EFB have a treatment function on chronic bronchitis by inhibiting inflammatory factors such as TNF-alpha, IL-1 beta and IL-6,and by increasing oxidation stress levels.
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Description

(1) Technical field

[0001] The present invention relates to a kind of white root extract and its application. (2) Background technology

[0002] Baiji is the dry tuber of orchid plant white and Bletilla striata (Thunb.) Reiehb.f., which has the effects of astringent and hemostasis, swelling and granulation, and is used for hemoptysis, hematemesis, traumatic bleeding, sore swelling, chapped skin, etc. disease. "Compendium of Materia Medica" states that it "can enter the lungs to stop bleeding, promote muscle regeneration and treat sores." It also has magical effects"; "Yifang Jijie" clearly records: white and ground powder, mixed with rice drink, can cure cough, lung impotence, hemoptysis and red phlegm. It can be seen that the curative effect of Baiji on lung diseases such as pulmonary fibrosis has long been recognized, and modern clinical application has further shown that Baiji alone has a good therapeutic effect on tuberculosis and silicosis, and combined with anti-tube...

Claims

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