Alliin antibody prepared through immunization of guinea pigs

An alliin, guinea pig technology, applied in the direction of anti-plant immunoglobulin, serum immunoglobulin, etc., can solve the problem of lack of immune antigen and antibody research.
CN108948192AActive Publication Date: 2018-12-07ZUNYI MEDICAL UNIVERSITY

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
ZUNYI MEDICAL UNIVERSITY
Publication Date
2018-12-07

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
Patent Text Reader

Abstract

The invention discloses an alliin antibody prepared through the immunization of guinea pigs. The alliin antibody contains an alliin antigen and a Freund's complete adjuvant, the alliin antigen and theFreund's complete adjuvant with equal amount are mixed to obtain an adjuvant antigen, the alliin antigen is injected into the body of a guinea pig, and the alliin antibody is obtained after the immune response. According to the alliin antibody, the immunogenicity of alliin is solved, the antibody is acquired through the immunization of the guinea pigs, and the alliin antibody can be applied to research of the concentration detection, in-vivo distribution and pharmacological action mechanisms of alliin and has important application values in the foundation and clinical researches of alliin.
Need to check novelty before this filing date? Find Prior Art

Description

Technical field

[0001] The invention belongs to the technical field of biological preparations, and particularly relates to an alliinine antibody prepared by immunization of guinea pigs. Background technique

[0002] Alliin is a water-soluble amino acid compound of garlic with stable chemical properties. In recent years, in vitro experimental studies have found that alliin has anti-microbial, anti-tumor, anti-oxidant, immune-regulating and cardiovascular effects. No clinical research has been seen so far. Report.

[0003] Low-molecular-weight compounds are generally not immunogenic. When combined with high-molecular compounds, they can activate the body's immune cells to produce corresponding antibodies. Alliin is a low-molecular-weight amino acid compound and has no immunogenicity. However, alliin has amino, carboxyl and thioether groups and can bind to protein molecules. Whether the conjugate is immunogenic and stimulates the body to produce antibodies. No related reports. To ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More