Proton application system for automatic and rapid detection of boron concentration and operation method thereof

A technology of application system and operation method, applied in the field of proton application system for automatic and rapid detection of boron concentration, can solve the problems of inability to meet detection requirements, high detection cost, large investment cost, etc., to improve performance and economy, and shorten detection time. , the effect of high integration

Pending Publication Date: 2018-12-25
DONGGUAN DONGYANGGUANG GAONENG MEDICAL EQUIP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In such a BNCT center, a large number of boron-containing blood samples need to be quickly quantitatively measured for boron concentration during the treatment process. The existing method of using ICP spectrometer to detect boron concentration in boron-containing blood samples cannot meet the detection requirements.
The main reasons are as follows: 1) One ICP spectrometer can only detect one boron-containing blood sample at the same time, and it takes several m

Method used

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  • Proton application system for automatic and rapid detection of boron concentration and operation method thereof
  • Proton application system for automatic and rapid detection of boron concentration and operation method thereof
  • Proton application system for automatic and rapid detection of boron concentration and operation method thereof

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Embodiment 1

[0059] Such as Figure 1A As shown, a proton application system for automatic and rapid detection of boron concentration includes: a low-energy linear accelerator system 100 , and an automatic and rapid detection system 300 for boron concentration of boron-containing samples.

[0060] Since neutron beams and boron elements undergo neutron capture nuclear reactions, prompt gamma rays can be produced, and the detection signal of the gamma rays produced by the detection device has a certain quantitative relationship with the concentration of boron-10 elements. Therefore, The boron concentration of the sample to be tested can be obtained by detecting the gamma ray information generated by the sample and converting it. At the same time, the production of neutron beams needs to be obtained by hitting a certain target with a high-speed proton beam to undergo a nuclear reaction.

[0061] The low-energy linear accelerator system 100 can generate proton beams and accelerate the energy o...

Embodiment 2

[0079] figure 2 It is a schematic structural diagram of a proton application system for automatic and rapid detection of boron concentration provided by Embodiment 2 of the present invention. The difference between this embodiment and Embodiment 1 is:

[0080] Also includes:

[0081] Beam switching system 200, for switching the proton beam;

[0082] The neutron capture therapy system 400 is used to treat tumor patients who meet the screening conditions for BNCT treatment.

[0083] The beam switching system 200 can switch the proton beam between the boron concentration automatic and rapid detection system 300 of the boron-containing sample and the neutron capture therapy system 400; When the detection system 300 starts to perform automatic rapid detection of boron-containing samples, when the beam switching system 200 switches the proton beam to the neutron capture therapy system 400, BNCT treatment starts.

[0084] Since the boron concentration automatic and rapid detectio...

Embodiment 3

[0091] image 3 A schematic structural diagram of a proton application system for automatic and rapid detection of boron concentration provided by Embodiment 3 of the present invention. The difference between this embodiment and Embodiment 1 is:

[0092] Also includes:

[0093] Beam switching system 200, for switching the proton beam;

[0094] The radionuclide production system 500 is used for radionuclide production and extraction.

[0095] The beam switching system 200 can switch the proton beam between the boron concentration automatic and rapid detection system 300 of the boron-containing sample and the radionuclide production system 500; When the detection system 300 is started, the automatic rapid detection of boron-containing samples is started. When the beam switching system 200 switches the proton beam to the radionuclide production system 500, the production and extraction of radionuclide is started.

[0096] Since the boron concentration automatic and rapid detec...

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Abstract

The invention belongs to the technical field of treatment, and discloses a proton application system for automatic and rapid detection of boron concentration. The proton application system for the automatic and rapid detection of the boron concentration comprises a low energy linear accelerator system used for generating proton beams and accelerating energy of the proton beams and an automatic boron-containing sample boron concentration rapid detection system which is used for automatic and rapid boron concentration quantitative measurement of batch boron samples and comprises a detection transmission section, a neutron irradiation device, an automatic boron-containing sample inlet device, a prompt gamma detection and analysis device, a beam current gathering device and a detection and control system. The proton application system can not only realize automatic and rapid detection of the boron concentration in the boron-containing samples, but also connect a neutron capture treatment system and/or a radionuclide production system at the same time, the device function is high, and the integration level is high. The invention further provides a boron-containing sample boron concentration rapid detection method. The efficiency of boron concentration detection for a large number of boron-containing samples is effectively improved and the cost of boron concentration detection is greatly reduced.

Description

technical field [0001] The invention relates to the technical field of radiotherapy, in particular to a proton application system for automatically and rapidly detecting boron concentration. Background technique [0002] Boron Neutron Capture Therapy (BNCT) is a bio-targeted binary radiotherapy mode with "drug-machine combination" and better safety. It has the advantages of radiotherapy, chemotherapy, heavy ion therapy and other means in principle Advantages, the most hopeful realization of human good wishes to cure tumors. BNCT treatment first injects non-toxic boron-carrying drugs with pro-tumor tissue into human blood, and after the boron (boron-10) drugs are enriched in tumor tissues, epithermal neutrons are used to irradiate the tumor site in a multi-directional conformal manner. When the protons meet the boron-10 nuclides in cancer cells and undergo a nuclear reaction, the released alpha particles and lithium-7 particles have strong lethality to cells, and the killing...

Claims

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Application Information

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IPC IPC(8): G01N23/2255A61N5/10
CPCA61N5/1007G01N23/2255A61N2005/109A61N2005/1087
Inventor 陈朝斌陈治均林育胜刘熔廖小丽
Owner DONGGUAN DONGYANGGUANG GAONENG MEDICAL EQUIP CO LTD
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