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Preparation of automatic cleaning paper-based sensing device and application of automatic cleaning paper-based sensing device in ion analysis

A technology for automatic cleaning and sensing devices, which is applied in measuring devices, analyzing materials, and analyzing materials by electromagnetic means. It can solve problems such as constraints on the development of paper chip analysis devices and waste of human resources, and achieve improved conductivity and specific surface area. , improve the signal strength, good specificity effect

Inactive Publication Date: 2019-01-22
UNIV OF JINAN
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, the cleaning operation of paper chips is particularly prominent. Repeated and tedious operations cause waste of human resources, which greatly restricts the development of paper chip analysis devices.

Method used

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  • Preparation of automatic cleaning paper-based sensing device and application of automatic cleaning paper-based sensing device in ion analysis
  • Preparation of automatic cleaning paper-based sensing device and application of automatic cleaning paper-based sensing device in ion analysis
  • Preparation of automatic cleaning paper-based sensing device and application of automatic cleaning paper-based sensing device in ion analysis

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Embodiment 1

[0040] The preparation method of the paper-based electrochemiluminescence sensing platform with automatic cleaning function is:

[0041] (1) Use Adobe illustrator CS4 software on the computer to design the hydrophobic wax printing pattern of the paper-based device with automatic cleaning function, the style is as attached figure 1 As shown, the three-dimensional multifunctional integrated paper-based device includes six wax printing areas A, B, C, D, E, and F, where the size of A, B, and C is 35×45 mm, and the size of D is 40×45 mm, the size of E and F are 30×45 mm, the diameter of the circular hollow channel on A and C is 14 mm, the width of the hydrophilic channel on B is 4 mm, and the entrance is a circular parent with a diameter of 8 mm. In the water zone, the outlet is a circular hydrophilic zone with a diameter of 14 mm. The electrode zones on E and F are semi-circular hydrophilic zones with a diameter of 14 mm. The spacing is 1.5 mm, and each zone has a width of 1 mm pitch...

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Abstract

The invention relates to preparation of an automatic cleaning paper-based electrochemical luminescence sensor and application of the automatic cleaning paper-based electrochemical luminescence sensorin heavy metal ion detection. A multi-channel cleaning area, a hollow channel area, a working electrode area, an auxiliary area and an absorption cleaning liquid area are prepared on a paper chip through a wax printing technology, and three electrodes are printed by virtue of a screen printing technology. By means of the hydrophilicity, designability and capillary action of paper, an automatic cleaning function of a paper chip device is realized by combining the multi-channel design. The signal is enhanced and the sensitivity of a system is improved by utilizing an intramolecular co-reaction agent and an intermolecular co-reaction agent of a luminescence reagent. The high-sensitivity and specific detection of the sensor can be realized by means of the inhibition effect of a specific DNA enzyme chain and mercury ions to nickel ions.

Description

Technical field [0001] The invention relates to the technical field of automatic cleaning paper-based sensor analysis and detection, and more specifically to the construction of a paper-based electrochemiluminescence sensor with automatic cleaning function and its application in double metal ion detection. Background technique [0002] In recent years, the problem of environmental pollution has become increasingly serious. Excessive heavy metal ions are one of the important factors of environmental pollution. As a kind of toxic micro-pollutants, heavy metal ions can be continuously transmitted and accumulated in the organism through the food chain in the ecosystem, which will affect the survival and health of human beings. Excessive heavy metal ions accumulated in a living body usually cause damage to the digestive tract, respiratory tract, liver and other organs, and even lead to the death of the living body. Therefore, it is imperative to find a simple, fast, efficient, accura...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/26G01N27/30G01N27/327G01N21/76
CPCG01N21/76G01N27/26G01N27/30G01N27/3278
Inventor 于京华黄煜真李丽
Owner UNIV OF JINAN
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