Manufacturing method of antihypertensive ointment for senile hypertension

A production method and high blood pressure technology, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems that active ingredients are not easy to penetrate the skin, and the onset of action is slow.

Inactive Publication Date: 2019-02-22
KUNMING MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the existing antihypertensive ointments usually have the defects that the active ingredients in the medicine are not easy to penetrate the skin, and the onset of action is slow.

Method used

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  • Manufacturing method of antihypertensive ointment for senile hypertension
  • Manufacturing method of antihypertensive ointment for senile hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A kind of preparation method of antihypertensive ointment for the elderly, comprising the following steps:

[0027] (1) Weigh the following raw materials according to parts by weight: 5 parts of Semen Cassiae, 12 parts of Eucommia ulmoides, 10 parts of Uncaria, 5 parts of Prunella vulgaris, 3 parts of Fructus chinensis, 4 parts of Gardenia, 2 parts of Ligustrum lucidum, 5 parts of Sangji 3 parts of chrysanthemum;

[0028] (2) Take mulberry and chrysanthemum, put them into a ground-bottomed flask, add 85% ethanol 10 times the sum of the two masses, heat in a water bath at 65° C. for 3 hours, and then filter to obtain a composite extract 1;

[0029] (3) Take cassia seed, Eucommia ulmoides, Uncaria, Prunella vulgaris, Fructus chinensis, gardenia, Ligustrum lucidum, crush through a 120 mesh sieve, add to a subcritical extraction tank, and feed n-butane under vacuum until complete Immerse the material, use a heating mantle to heat the temperature inside the extraction tank ...

Embodiment 2

[0033] A kind of preparation method of antihypertensive ointment for the elderly, comprising the following steps:

[0034] (1) Weigh the following raw materials according to parts by weight: 10 parts of Semen Cassiae, 7 parts of Eucommia, 15 parts of Uncaria, 2 parts of Prunella vulgaris, 7 parts of Fructus chinensis, 1 part of Gardenia, 6 parts of Ligustrum lucidum, 1 part of Sangjisi 6 parts of chrysanthemum;

[0035] (2) Take mulberry and chrysanthemum, put them into a ground-bottomed flask, add 85% ethanol which is 7 times the sum of the two masses, and filter after heating in a water bath at 70°C for 3 hours to obtain a composite extract 1;

[0036] (3) Take cassia seed, Eucommia ulmoides, Uncaria, Prunella vulgaris, Fructus chinensis, gardenia, Ligustrum lucidum, crush through a 100-mesh sieve, add to a subcritical extraction tank, and feed n-butane under vacuum until complete Immerse the material, use a heating mantle to heat the temperature inside the extraction tank ...

Embodiment 3

[0040] A kind of preparation method of antihypertensive ointment for the elderly, comprising the following steps:

[0041] (1) Weigh the following raw materials according to parts by weight: 5 parts of Semen Cassiae, 7 parts of Eucommia, 15 parts of Uncaria, 5 parts of Prunella vulgaris, 3 parts of Fructus chinensis, 1 part of Gardenia, 6 parts of Ligustrum lucidum, 5 parts of Sangji 3 parts of chrysanthemum;

[0042] (2) Take mulberry and chrysanthemum, put them into a ground-bottomed flask, add 85% ethanol which is 7 times the sum of the two masses, and filter after heating in a water bath at 70°C for 3 hours to obtain a composite extract 1;

[0043] (3) Take cassia seed, Eucommia ulmoides, Uncaria, Prunella vulgaris, Ultima chinensis, gardenia, Ligustrum lucidum, crush through a 120 mesh sieve, add to a subcritical extraction tank, and feed n-butane under vacuum until complete Immerse the material, use a heating mantle to heat the temperature inside the extraction tank to ...

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Abstract

The invention provides a manufacturing method of antihypertensive ointment for senile hypertension. The manufacturing method comprises the following steps that (1) the following raw materials in partsby weight: 5-10 parts of cassia seeds, 7-12 parts of barks of eucommia, 10-15 parts of ramulus et uncus uncariae, 2-5 parts of common selfheal fruit-spike, 3-7 parts of fructus leonuri, 1-4 parts offructus gardeniae, 2-6 parts of fructus ligustri lucidi, 1-5 parts of herba taxilli and 3-6 parts of flos chrysanthemi are weighed; (2) first compound extract is prepared; (3) second compound extractis prepared; (4) Fe85.5Cr2.5O7.5B2.5C2 alloy powder is subjected to passivation treatment; and (5) the antihypertensive ointment for hypertension is prepared. The antihypertensive ointment obtained bythe manufacturing method has the effects of significantly expanding the coronary artery, relaxing blood vessels and increasing the coronary blood flow, through compatibility of the herba taxilli andthe flos chrysanthemi, the effect of increasing the coronary blood flow and the effects of improving heart activity, strengthening the heart and resisting arrhythmia can be achieved, and the good antihypertensive effect is achieved.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a preparation method of a high blood pressure antihypertensive ointment for the elderly. Background technique [0002] Hypertension (hypertension) refers to an increase in systemic arterial blood pressure (systolic and / or diastolic) as the main feature (systolic blood pressure ≥ 140 mm Hg, diastolic blood pressure ≥ 90 mm Hg), which may be accompanied by heart, brain, kidney, etc. Clinical syndrome of functional or organic damage to organs. Hypertension is the most common chronic disease and the main risk factor for cardiovascular and cerebrovascular diseases. The blood pressure of a normal person fluctuates within a certain range with changes in the internal and external environment. [0003] At present, the commonly used antihypertensive drugs include hydrochlorothiazide, propranolol, captopril, etc. These drugs are generally taken in the form of taking ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/744A61K47/24A61P9/12A61K9/06
CPCA61K9/06A61K36/185A61K36/287A61K36/46A61K36/482A61K36/533A61K36/536A61K36/638A61K36/74A61K36/744A61K47/24A61K2236/333A61K2236/37A61P9/12A61K2300/00
Inventor 冉凌云杜梦琦冉圆圆张江叶琴
Owner KUNMING MEDICAL UNIVERSITY
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