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Medicine compound for treating thyroid nodule and preparation method and application thereof

A technology for thyroid nodules and a composition is applied in the field of pharmaceutical compositions for treating thyroid nodules and the field of preparation thereof, which can solve the problems that patients with thyroid nodules cannot be effectively controlled, and achieves the treatment of thyroid nodules with good safety and no toxic side effects

Active Publication Date: 2019-04-05
TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the clinical treatment measures for thyroid nodules include TSH suppression therapy, 131 I treatment, ultrasound-guided percutaneous ethanol injection (PEI), percutaneous laser ablation, radiofrequency ablation, surgery, etc., but there are still some patients with thyroid nodules that cannot be effectively controlled
And there is no report that the pharmaceutical composition of the present invention is used for the treatment of thyroid nodules

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1, the preparation of pharmaceutical composition of the present invention

[0023] 1. Raw materials: Rhizoma Cyperi 12g, Radix Paeoniae Alba 12g, Seaweed 20g, Bupleurum 10g, Kelp 15g, Fritillaria 35g, Pinellia 10g, Green Peel 6g, Tangerine Peel 10g, Angelica 15g, Chuanxiong 10g, Forsythia 10g, raw oyster 15g, Prunella vulgaris 9g.

[0024] 2. Preparation method: according to the ratio of the above raw materials, first put Fritillaria fritillaria and raw oysters into a casserole, add 3000mL of water, boil for half an hour on a high fire, then add Cyperus Cyperi, Radix Paeoniae Alba, Seaweed, Bupleurum, Pinellia, Green peel, tangerine peel, angelica, chuanxiong, forsythia, kelp, Prunella vulgaris, bring to a boil over a strong fire (high fire), then continue to boil over a slow fire (low fire) until about 150-200mL, and pour the cooked liquid into a clean container. Add 1500mL of water to the above-mentioned remaining medicinal residues, first boil with high h...

Embodiment 2

[0025] Embodiment 2, the preparation of pharmaceutical composition of the present invention

[0026] 1. Raw materials: Rhizoma Cyperi 15g, Radix Paeoniae Alba 15g, Seaweed 16g, Bupleurum 8g, Kelp 12g, Fritillaria 45g, Pinellia 12g, Green Peel 5g, Tangerine Peel 8g, Angelica 18g, Chuanxiong 12g, Forsythia 12g, raw oyster 12g, Prunella vulgaris 7g.

[0027] 2, preparation method: with embodiment 1.

Embodiment 3

[0028] Embodiment 3, the preparation of pharmaceutical composition of the present invention

[0029] 1. Raw materials: Rhizoma Cyperi 9g, Radix Paeoniae Alba 9g, Seaweed 24g, Bupleurum 12g, Kelp 18g, Fritillaria 30g, Pinellia 8g, Green Peel 7g, Tangerine Peel 12g, Angelica 12g, Chuanxiong 8g, Forsythia 8g, raw oyster 18g, Prunella vulgaris 11g.

[0030] 2, preparation method: with embodiment 1.

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PUM

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Abstract

The invention provides a medicine compound for treating thyroid nodule. The medicine compound for treating thyroid nodule is a preparation prepared from the following raw material medicines in parts by weight: 9-15 parts of rhizoma cyperi, 9-15 parts of radix paeoniae alba, 16-24 parts of alga, 8-12 parts of radix bupleuri, 12-18 parts of kelp, 30-45 parts of fritillary bulb, 8-12 parts of rhizomapinelliae, 5-7 parts of pericarpium citri reticulatae viride, 8-12 parts of pericarpium citri reticulatae, 12-18 parts of angelica sinensis, 8-12 parts of rhizoma chuanxiong, 8-12 parts of fructus forsythiae, 12-18 parts of raw oyster shell and 7-11 parts of selfheal. Experiment results prove that the medicine compound has a precise and appropriate formula, can significantly relieve clinical symptoms of a thyroid nodule patient, and effectively treats thyroid nodule, moreover, the compound is good in safety, free from toxic and side effects and convenient to use, and a novel medicine option is provided for clinics.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating thyroid nodules, a preparation method and application thereof. Background technique [0002] Thyroid nodules refer to one or more lumps with abnormal tissue structure in the thyroid due to various reasons. They are scattered lesions caused by local abnormal growth of thyroid cells. They can move up and down with the swallowing action and the thyroid gland. disease, frequently-occurring disease. Although thyroid nodules do not directly pose a threat to life safety, the nodules compress surrounding tissues: compression of the recurrent laryngeal nerve leads to paralysis of the vocal cords, causing hoarseness; compression of the trachea, resulting in chest tightness, dyspnea and discomfort; Difficulty swallowing; compression of blood vessels, resulting in difficulty in blood return, causing the patient's face to be blue and edema...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61P43/00A61K35/618
CPCA61K35/618A61K36/02A61K36/03A61K36/232A61K36/233A61K36/236A61K36/536A61K36/634A61K36/65A61K36/71A61K36/752A61K36/8888A61K36/8905A61K36/8966A61P43/00A61K2300/00
Inventor 廖婷婷黄群张传涛
Owner TEACHING HOSPITAL OF CHENGDU UNIV OF T C M
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