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External-use traditional Chinese medicine preparation for treating peripheral neuropathy caused by chemotherapy drugs

A technology for peripheral neuropathy and external preparations, which can be used in nervous system diseases, drug combinations, medical preparations containing active ingredients, etc., and can solve problems such as poor treatment effects

Inactive Publication Date: 2019-07-05
夏小军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, vitamins such as methylcobalamin are often used as adjuvant therapy in clinical treatment, and the therapeutic effect is poor. The external treatment of traditional Chinese medicine has the characteristics of direct action and non-invasiveness, and the clinical treatment has a high effective rate. It is effective for peripheral neuropathy caused by chemotherapy drugs The treatment has important clinical significance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Embodiment 1, the preparation of powder medicine

[0064] Raw material formula (by weight): 10 parts of cooked aconite, 10 parts of cassia twig, 20 parts of astragalus, 20 parts of angelica, 20 parts of Caulis Spatholobus, 10 parts of safflower, 10 parts of Chuanxiong, 10 parts of Eucommia, 10 parts of mulberry, 10 parts of Dipsacus chuanxiong, 10 parts of Epimedium, 10 parts of Gastrodia elata, 10 parts of Uncaria, 10 parts of silkworm, 10 parts of Speranthemus, and 10 parts of Shenjincao.

[0065] The above-mentioned raw materials are prepared into powder according to the conventional process for preparing powder in pharmacy; specification, 100g / bag.

[0066] Usage and dosage, 1-2 times a day, 100g each time, dissolve with 1200mL warm water and soak the affected area, raise the temperature of the remaining solution to 40°C, soak for 20-30 minutes, 14 days is a course of treatment.

Embodiment 2

[0067] Embodiment 2, the preparation of ointment medicine

[0068] Raw material formula (by weight): 10 parts of cooked aconite, 10 parts of cassia twig, 20 parts of astragalus, 20 parts of angelica, 20 parts of Caulis Spatholobus, 10 parts of safflower, 10 parts of Chuanxiong, 10 parts of Eucommia, 10 parts of mulberry, 10 parts of Dipsacus chuanxiong, 10 parts of Epimedium, 10 parts of Gastrodia elata, 10 parts of Uncaria, 10 parts of silkworm, 10 parts of Speranthemus, and 10 parts of Shenjincao.

[0069] The above-mentioned raw materials are prepared into ointment according to the conventional process and auxiliary materials for preparing ointment in pharmacy; 25g / bag.

[0070] How to use: 1-2 times a day, 25g each time, dissolve in 1200mL of warm water and soak the affected area at a temperature of 40°C for 20-30 minutes, 14 days is a course of treatment.

Embodiment 3

[0071] Embodiment 3, the preparation of effervescent medicine

[0072] Raw material formula (by weight): 10 parts of cooked aconite, 10 parts of cassia twig, 20 parts of astragalus, 20 parts of angelica, 20 parts of Caulis Spatholobus, 10 parts of safflower, 10 parts of Chuanxiong, 10 parts of Eucommia, 10 parts of mulberry, 10 parts of Dipsacus chuanxiong, 10 parts of Epimedium, 10 parts of Gastrodia elata, 10 parts of Uncaria, 10 parts of silkworm, 10 parts of Speranthemus, and 10 parts of Shenjincao.

[0073] The above-mentioned raw materials are prepared into an effervescent agent according to the conventional process and auxiliary materials for preparing an effervescent agent in pharmacy; each tablet is 5g.

[0074] How to use: 1-2 times a day, 10g each time, dissolve in 1200mL of warm water and soak the affected area at a temperature of 40°C for 20-30 minutes, 14 days is a course of treatment.

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PUM

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Abstract

The invention discloses an external-use traditional Chinese medicine preparation for treating peripheral neuropathy caused by chemotherapy drugs. The external-use traditional Chinese medicine preparation is prepared by combining processed radix aconiti carmichaeli, ramulus cinnamomi, radix astragali, angelica sinensis, caulis spatholobi, carthamus tinctorius, rhizoma chuanxiong, cortex eucommiae,loranthus parasiticus, dipsacus asper, herba epimedii, rhizoma gastrodiae, uncaria, white muscardine silkworm, Phryma leptostachya and lycopodium clavatum. The external-use traditional Chinese medicine preparation has the advantages that the preparation has effects of warming yang and dispelling cold and promoting blood circulation to remove blood stasis; the external-use preparation has a good curative effect on the peripheral neuropathy caused by the chemotherapy drugs, and the total effective rate of the preparation reaches 95%; in addition, the preparation is prepared by pure traditional Chinese medicine materials, can be coordinated with the chemotherapy of tumor patients to prevent and treat the peripheral neuropathy caused by the chemotherapy drugs, and has a good preventing and treating effect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicinal preparation for preventing and treating peripheral neuropathy caused by chemotherapy drugs, and is mainly used for preventing and treating peripheral neuropathy caused by chemotherapy drugs. Background technique [0002] The incidence of chemotherapy-induced peripheral neuropathy (CIPN) has gradually increased in recent years, seriously affecting the life and quality of life of patients. At the same time, for some drugs, CIPN is even dose-limiting toxicity, which seriously Affect the clinical application of chemotherapy drugs. Common chemotherapeutic drugs that cause peripheral neurotoxicity mainly include platinum derivatives, vinblastines, taxanes, and alkylating agents. The main clinical manifestations are: numbness of extremities, paresthesia, hypoesthesia, pain, muscle spasm, muscle weakness, myalgia, and even paralysis in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P25/02A61K35/64
CPCA61K35/64A61K36/11A61K36/185A61K36/232A61K36/236A61K36/286A61K36/296A61K36/46A61K36/47A61K36/481A61K36/486A61K36/54A61K36/714A61K36/74A61K36/8988A61P25/02A61K2300/00
Inventor 夏小军
Owner 夏小军
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