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Chrysanthemum stem and leaf multi-component granule capable of improving intestinal function, its preparation method and application

A technology of intestinal function and granules, which is applied in the fields of chrysanthemum stem and leaf multi-component granules that can improve intestinal function and its preparation and application, can solve problems such as water source and soil pollution, threats to human health, etc., and reduce inflammation indicators , Improve stool properties and blood in the stool score, increase the effect of content

Active Publication Date: 2022-03-11
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term use of antibiotics has caused water and soil pollution, and the emergence of drug-resistant bacteria caused by antibiotic abuse has seriously threatened human health

Method used

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  • Chrysanthemum stem and leaf multi-component granule capable of improving intestinal function, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] 1. A chrysanthemum stem and leaf multi-component granule with improved intestinal function, which is composed of the following extracts and auxiliary materials in percentage by weight: 1% of chrysanthemum stem and leaf volatile oil, 1.6% of chrysanthemum stem and leaf water extract, chrysanthemum stem and leaf ethanol Extract 13.4%, powdered sugar 84%. Mix the above-mentioned several raw materials except volatile oil with a mixer, add a little 70% ethanol to make a soft material, pass through a 14-mesh nylon sieve to granulate, dry the wet granules at 60°C, and slowly stir, spray into 1 % volatile oil from stems and leaves of chrysanthemum and sealed for 30 minutes, left to stand, filled, sealed, and stored in a refrigerator at 4°C. For oral administration, shake well when used.

[0034] 2. A method for preparing chrysanthemum stem and leaf multi-component granules capable of improving intestinal function, comprising the following steps:

[0035] (1) Take fresh chrysa...

Embodiment 2

[0040] A chrysanthemum stem and leaf multi-ingredient granule capable of improving intestinal function, which is composed of the following extracts and auxiliary materials in percentage by weight: 1% of chrysanthemum stem and leaf volatile oil, 3% chrysanthemum stem and leaf water extract, chrysanthemum stem and leaf ethanol extract 12%, powdered sugar 84%. Mix the above-mentioned raw materials with a mixer, add a little 70% ethanol to make a soft material, pass through a 14-mesh nylon sieve to granulate, dry the wet granules at 60°C, and slowly stir, spray 1% of chrysanthemum stems and leaves The volatile oil is sealed and stored for 30 minutes, then left to stand, filled, sealed, and stored in a refrigerator at 4°C.

[0041] Wherein the chrysanthemum stem and leaf volatile oil, the preparation method of the chrysanthemum stem and leaf water extract and the chrysanthemum stem and leaf ethanol extract are the same as in Example 1.

Embodiment 3

[0043] A chrysanthemum stem and leaf multi-ingredient granule capable of improving intestinal function, which is composed of the following extracts and auxiliary materials in percentage by weight: 1% chrysanthemum stem and leaf volatile oil, 5% chrysanthemum stem and leaf water extract, chrysanthemum stem and leaf ethanol extract 10%, powdered sugar 84%. Mix the above-mentioned raw materials with a mixer, add a little 70% ethanol to make a soft material, pass through a 14-mesh nylon sieve to granulate, dry the wet granules at 60°C, and slowly stir, spray 1% of chrysanthemum stems and leaves The volatile oil is sealed and stored for 30 minutes, then left to stand, filled, sealed, and stored in a refrigerator at 4°C.

[0044] The preparation methods of chrysanthemum stem and leaf volatile oil, chrysanthemum stem and leaf water extract and chrysanthemum stem and leaf ethanol extract are the same as in Example 1.

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Abstract

The invention discloses a chrysanthemum stem and leaf multi-component granule capable of improving intestinal function and its preparation method and application. composition of excipients. The present invention is prepared through a large number of tests and screens, and is prepared by compounding natural chrysanthemum stems and leaves that can improve intestinal function. The experimental results show that the extract has a good ability to regulate the balance of intestinal flora and correct disordered intestinal metabolism. And nutritional value, can significantly repair hemorrhagic necrotizing enteritis, bacterial enteritis and ulcerative colitis caused by endotoxin. The preparation method provided by the invention is simple, convenient, and highly automated. It uses chrysanthemum stems and leaves as raw materials, turns waste into treasure, can well retain the active ingredients in the raw materials, has no toxic and side effects, and can be used as a feed additive for animal husbandry. Or it can be used to prepare functional feed, which has important application prospects.

Description

technical field [0001] The invention relates to a chrysanthemum stem-leaf multi-component granule capable of improving intestinal function, a preparation method and application thereof. Background technique [0002] Enteritis caused by toxins, pathogenic microorganism infection and chronic inflammatory stimuli seriously affects and restricts the development of animal husbandry. At present, low-dose antibiotic feeding is mostly used for the purpose of reducing the occurrence of economic animal diseases and short-term fattening. Long-term use of antibiotics has caused water and soil pollution, and the emergence of drug-resistant bacteria caused by the abuse of antibiotics has seriously threatened human health. At present, various policies have been introduced around the world to restrict the use of antibiotics. Traditional Chinese medicine and natural products are rich in various types of chemical components, providing a rich library of candidate compounds. Natural products a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/287A61K47/26A61P1/00A61P1/04A61K127/00A61K135/00
CPCA61K36/287A61K9/1623A61P1/00A61P1/04A61K2236/331A61K2236/333
Inventor 魏丹丹段金廒常相伟郭盛严辉钱大玮
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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