38results about How to "Improve stool properties" patented technology

The invention discloses a functional food capable of relaxing bowel and alleviating constipation. The active ingredients of the functional food comprise 20-40 parts of bunge cherry seed extracts, 20-40 parts of hemp seed extracts, 15-35 parts of dietary fibers, 15-35 parts of aloe extracts and 10-30 parts of cassia seed extracts. The invention further provides a preparation method of the functional food cable of relaxing the bowel and alleviating the constipation. The preparation method comprises the following steps that firstly, the powdered raw materials of all the active ingredients are put into a stirring machine and stirred to be uniform, a powdered mixture is obtained; secondly, the powdered mixture is dried and sterilized; thirdly, the dried and sterilized powdered mixture passes through a 60-100 mesh screen, and then the powdery functional food capable of relaxing the bowel and alleviating the constipation is obtained. All the active ingredients are cooperated and mutually complemented and promoted in scientific proportion, and the powerful and complete functions of relaxing the bowel and alleviating the constipation are brought into play.

The invention discloses an Bifidobacterium animal subspecies lactis JMCC0025. The strain of JMCC0025 was deposited in General Microbiology Center of China Microbiological Culture Collection ManagementCommittee on August 20, 2019, the deposit address is No. 3, yard 1, Beichen West Road, Chaoyang District, Beijing, and the deposit number is CGMCC NO. 18403; and the invention also discloses a methodof isolation and purification and application of the above Bifidobacterium animal subspecies lactis JMCC0025. The Bifidobacterium animal subspecies lactis JMCC0025 provided by the present invention can regulate intestinal flora balance, improve fecal characteristics, and has better better survival rate of simulated digestive fluid; and under the storage condition of 37 DEG C, which is suitable for the growth of lactic acid bacteria, the post-acid can be well controlled. The invention belongs to the technical field of bioengineering, and the provided Bifidobacterium animal subspecies lactis JMCC0025 has the function of regulating intestinal flora balance, and can be used in the process of making food, medicine or beverage.

The invention discloses an application of lactobacillus rhamnosus to preventing and relieving ulcerative colitis, and belongs to the technical field of functional microorganisms. The lactobacillus rhamnosus can tolerate the gastrointestinal environment of a human body, significantly reduce weight loss during the period of ulcerative colitis, improve fecal traits and hematochezia, improve colon mucosal injury, reduce MPO activity, and reduce the content of proinflammatory factors TNF-alpha, IL-1beta, IL-6 and IFN-gamma in colon. The transcription levels of colon close junction related proteins Claudin-3, ZO-1, ZO-2 and Occludin, antibacterial peptides Reg3g and Reg3b and mucoprotein MUC2 are up-regulated, the abundance of short-chain fatty acid producing bacteria Coprococcus and Faecalibacterium and the content of short-chain fatty acid are improved, the abundance of beneficial bacteria Lactobacillus in intestinal tracts is increased, the abundance of the conditional pathogenic bacteria Acinetobacter is reduced, and the abundance and diversity of intestinal flora are increased.

The invention discloses a Chinese herb extract composition for treating functional gastrointestinal disorder or irritable bowel syndrome, a preparation method and application of the composition to preparation of a medicine. The Chinese herb extract composition comprises the following Chinese medicinal herb extracts in parts by weight: 13-29 parts of langehead atractylodes rhizome extract I, 18-57 parts of langehead atractylodes rhizome extract II, 13-53 parts of radix paeoniae alba extract, 6-32 parts of pericarpium citri reticulatae extract and 2-27 parts of divaricate saposhnikovia root extract, wherein the langehead atractylodes rhizome extract I is an extract of a distillation method or supercritical extraction method; the langehead atractylodes rhizome extract II is a water extract; the radix paeoniae alba extract is an alcohol extract; the pericarpium citri reticulatae extract is an alcohol extract; the divaricate saposhnikovia root extract is an aqueous extract or supercritical extract. According to the Chinese herb extract composition, the conventional view that co-decocting or total extracting of a Chinese herbal compound is superior to respective extracting of each Chinese medicinal herb is overcome, the pharmacological effect is remarkably improved through optimized combined treatment of each Chinese medicinal herb extract, and the quality control of the composition is facilitated. The Chinese herb extract composition for treating functional gastrointestinal disorder or irritable bowel syndrome, disclosed by the invention, has an unexpected effect.

The invention provides bifidobacterium longum subsp. Longum KLDS K5 capable of preventing and relieving symptoms of colitis, and belongs to the technical field of microorganisms. The invention further provides a preparation method of the bifidobacterium longum subsp. Longum KLDS K5. Experiments show that the bifidobacterium longum provided by the invention can tolerate the human gastrointestinal environment, relieve weight loss in the ulcerative colitis disease period, improve colonic mucosa injury and reduce MPO activity, and inhibit oxidation-related factors through iNOS and COX-2 signal pathways so as to relieve inflammatory bowel diseases; nF-kappa B p65 nuclear transfer is inhibited through a TLR4/MyD88/NF-kappa B signal channel, the expression quantity of proinflammatory factors TNF-alpha, IL-1beta, IL-6 and IL-10 in colon is reduced, the transcriptional level of colon tight connection related proteins Claudin-1, ZO-1 and Occludin and mucoprotein MUC2 is up-regulated, the intestinal flora change after DSS induction can be improved in the genus level, and the richness and diversity of the intestinal flora are improved.

The invention discloses a traditional Chinese medicine preparation for relaxing bowel and expelling toxin and a preparation method thereof. The traditional Chinese medicine comprises raw materials of an aloe dry powder, polygonum multiflorum, radix astragali and Radix Ophiopogonis. Raw materials includin polygonum multiflorum, radix astragali and Radix Ophiopogonis are leached for power process, the power is blended with the aloe dry powder, and the mixture is filled in capsules. The product is not only safe for administration, but also has significant disease control effect and low industrialized production cost.

The invention discloses a health care composition, an oral liquid and a health care product for relaxing bowels and improving organism immunity, and a preparation method of the health care composition, the oral liquid and the health care product. The composition is prepared by mixing extractives extracted from semen cassiae, polygonum multiflorum and gynostemma pentaphyllum by enthanol with fructooligosaccharide; a sugar aspartame sweetener and a citric acid additive are added to the prepared health care composition and filled to be prepared into the oral liquid; corresponding pharmaceutical necessities can also be added to be prepared into a capsule or troche, the health care composition, the oral liquid and the health care product have functions of relaxing the bowels and improving the organism immunity, and have no adverse reactions to body health, and the preparation method of the health care composition, the oral liquid and the health care product is simple; no additional cost exists; and the method can be widely used for industrial production.

The invention discloses application of peimisine in preparation of medicines for preventing and/or treating ulcerative colitis, and relates to the field of medicines. Experiments prove that the peimisine has no significant influence on experimental mice: the experimental mice in a peimisine group have no death, no significant change in body weight, no obvious lesion in intestinal tissues, no obvious pathological symptoms in colon and cecum, and the peimisine has certain safety. The peimisine can reduce the weight loss rate of a mouse with the ulcerative colitis, can improve the fecal character and hemafecia condition of the mouse with the ulcerative colitis, can improve DAI of the mouse with the ulcerative colitis, and can effectively prevent and improve pathological damage of intestinal tissues of the mouse with the ulcerative colitis; and therefore, the peimisine has particularly excellent anti-ulcerative colitis activity and certain safety, and can obviously improve the ulcerative colitis symptom.

The invention belongs to the technical field of medicine, in particular to a traditional Chinese medicine composition for treating qi stagnation type post-PPH (procedure for prolapse and hemorrhoids) constipation. The composition comprises following herbs by weight: Lithocarpus dealbatus inflorescence 4-8 parts, Caulis Perillae Furtescentis 4-8 parts, Herba Andrographitis Laxiflorae 5-13 parts, Folium Perillae Frutesentis 4-8 parts, Herba Gerberae Piloselloidis 4-8 parts, Radix Gmelinae Delauayanae 4-8 parts, Fructus Citri Grandis 4-8 parts, Herba Doronici Altaici 4-8 parts, Flos Cheiranthus 4-8 parts, Fructus Bothocaryum 4-8 parts, and Radix Glycyrrhizae 4-8 parts. The herbs are jointly effective in facilitating lung and promoting qi circulation and loosening the bowel to relieve constipation, are safe and effective in treating qi stagnation type post-PPH constipation, and can significantly improve stool property and relive constipation symptoms such as anal obstructive feeling, laborious defecation, tenesmus and defecation pain.

The invention relates to a traditional Chinese medicine composition granule for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine composition granule is prepared from tens of traditional Chinese herbs of costustoot, agilawood, fructus aurantii, sanders, rheum officinale, mangnolia officinalis, muak, defatted croton seed powder, date and ligusticum wallichii. The traditional Chinese medicine composition granule is mainly used for treating diseases of acute diarrhea, irritable bowel syndrome and the like in clinic.

The invention belongs to the technical field of drug preparations, and particularly relates to a composition for treating uclerative colitis as well as granules and a preparation method thereof. The composition is prepared from the following components in parts by weight: 5-12 parts of radix scutellariae, 1-5 parts of rhizoma coptidis, 5-10 parts of cortex phellodendri and 4-10 parts of treated folium artemisiae argyi. The granules are prepared from the following raw materials in parts by weight: 15-37 parts of the composition for treating ulcerative colitis, 0.5-2 parts of a sweetening agent,0.5-2 parts of micro powder silica gel, 1-3 parts of sucrose fatty acid ester, 0.5-1.5 parts of crospolyvinyl pyrrolidone and 3-6 parts of microcrystalline cellulose. The composition for treating ulcerative colitis has an outstanding treatment effect on ulcerative colitis; meanwhile, the granules prepared by applying the composition have good stability, are uniformly dispersed after being dissolved in water, has good taste and low toxic and side effects, and is suitable for being applied and popularized.

The invention discloses an application of a molybdenum-based polyoxometallate cluster in treatment of inflammatory diseases. The inflammatory disease is related to the rising of the ROS level. Experiments show that the molybdenum-based polyoxometallate cluster achieves the purpose of preventing or treating inflammatory diseases by reducing the ROS level in tissues. Therefore, the molybdenum-based polyoxometallate cluster can be used for preparing the medicine for treating the inflammatory diseases, the application of the molybdenum-based polyoxometallate cluster is widened, the new medicine for treating the inflammatory diseases is developed, an experimental basis is provided for treating clinical inflammatory diseases by the molybdenum-based polyoxometallate cluster, and the molybdenum-based polyoxometallate cluster has a good application prospect. The invention also provides a medicine for treating inflammatory diseases. The medicine for treating the inflammatory diseases can be used for effectively treating the inflammatory diseases.

The invention relates to a pharmaceutical component capable of preventing and/or treating Diarrhea Predominant Irritable Bowel Syndrome (IBS-D), and a preparation method and an application thereof. The pharmaceutical component contains roasted radix astragali, fried bighead atractylodes rhizome, radix paeoniae alba, rhizoma corydalis, fructus alpiniae oxyphyllae, fried gordon euryale, finger citron, fried cortex ailanthi and nutmegs. The pharmaceutical component has the following effects: (1) improving clinical symptoms of a patient significantly; (2) relieving an abdominal pain degree of thepatient and improving properties of stool of the patient effectively; (3) improving life quality of the patient obviously; (4) reducing a serum 5-HT level of the patient obviously; and (5) being low in recurrence rate.

The invention belongs to the technical field of medicaments, and particularly relates to a traditional Chinese medicine composition for treating qi and yang deficiency type constipation after a hemorrhoids PPH (Procedure for Prolapse and Hemorrhoids) surgery. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicaments in parts by weight: 4 to 8 parts of Juglans mandshurica Maxim nuts, 4 to 8 parts of walnut oil, 4 to 8 parts of Ficus esquiroliana, 4 to 8 parts of root of bilobed grewia, 5 to 13 parts of Andrographis laxiflora, 4 to 8 parts of white perilla leaf, 4 to 8 parts of herba gerberae piloselloidis, 4 to 8 parts of Pimpinella coriacea, 4 to 8 parts of piper sarmentosum, 4 to 8 parts of Gmelina delavayana, 4 to 8 parts of immature fruit of Pummelo, 4 to 8 parts of Doronicum altaicum Pallas, 4 to 8 parts of English wallflower, 4 to 8 parts of Cornus controversa fruits and 4 to 8 parts of Glycyrrhiza uralensis. The traditional Chinese medicine composition has the effects of diffusing the lung and promoting the circulation of qi, invigorating qi and warming yang, relaxing the bowels and removing stagnancy after combined use of all the medicinal materials, is safe and effective to treat the constipation (qi and yang deficiency type) after the PPH surgery, and can be used for remarkably improving the stool property and alleviating the constipation symptoms, such as blockage sense of anus, strenuosity sense of defecation, tenesmus sense, defecation pain sense and the like.

The invention discloses application of sipeimine in preparation of medicines for preventing and/or treating ulcerative colitis, and relates to the field of medicines. According to the invention, experiments prove that the sipeimine does not cause significant influence on experimental mice: there is no death, no significant change in body weight, no obvious lesion in intestinal tissues and no obvious pathological symptoms in colon and cecum for the experimental mice in a sipeimine group, showing that the sipeimine has certain safety. The sipeimine can reduce the weight loss rate of mice with ulcerative colitis, improve the fecal character and the hemafecia condition of the mice with ulcerative colitis, improve DAI of the mice with ulcerative colitis and effectively prevent and improve pathological damage of intestinal tissues of the mice with ulcerative colitis, suggesting that the sipeimine has particularly excellent anti-ulcerative colitis activity and certain safety, and can obviously improve ulcerative colitis symptoms.