14 results about "Functional gastrointestinal disorder" patented technology

This invention provides a probiotic composition for improving diarrhea and its uses. The probiotic composition of this invention comprises space-occupying bacteria, organic acid-producing bacteria, and oxygen-depleting bacteria, wherein the oxygen-depleting bacteria are *Weizmannii*, the organic acid-producing bacteria are *Lactobacillus* or *Lactobacillus lactis*, and the space-occupying bacteria are *Bifidobacterium*. The probiotic composition of this invention can effectively improve diarrhea and is therefore suitable for the prevention and / or treatment of diarrhea-related functional gastrointestinal disorders.

The present invention relates to the field of therapeutic compositions for gastrointestinal disorders. More particularly, the invention refers to compositions comprising resveratrol, saffron extract and vitamin D, and to the use thereof for the treatment of functional gastrointestinal disorders, and in particular for the treatment of irritable bowel syndrome (IBS).

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating co-disease of liver depression and spleen deficiency type depressive state and IBS (irritable bowel syndrome). The composition comprises radix pseudostellariae, poria cocos, raw coix seeds, fingered citron, polygala tenuifolia, roasted rhizoma atractylodis macrocephalae, lotus seed pulp, mint, roses, lilies, raw fructus gardeniae, fermented soybeans and raw hawthorn fruits. Liver soothing, depression relieving, spleen strengthening and heart nourishing are taken as core treatment rules, heat clearing, restlessness relieving, digestion promoting and stagnation removing are also taken, and the complex pathogenesis that the two are causal to each other is formed for gastrointestinal dysfunction caused by emotional discomfort. The formula is characterized in that the three internal organs of the heart, the liver and the spleen are treated at the same time, the four methods of tonifying, dredging, clearing and eliminating are used at the same time, balance is achieved between qi regulating and healthy qi supporting, and the formula is suitable for patients suffering from complex heart and body diseases with low mood, anxiety, dysphoria, insomnia, amnesia, abdominal fullness, inappetence, loose stool or loose stagnation.

The invention relates to the field of organic chemistry and pharmacy and provides a novel compound [2-(dimethylamino)-2-phenylbutyl]-3,4,5-trimethoxybenzoate 4-methyl-2H-chromen-2-on-7-yl sulphate, a method for treating and preventing functional gastrointestinal disorders, which comprises administering an effective amount of compound [2-(dimethylamino)-2-phenylbutyl]-3,4,5-trimethoxy benzoate 4-methyl-2H-chromen-2-on-7-yl sulphate to a patient in need thereof, a pharmaceutical composition based on compound [2-(dimethylamino)-2-phenylbutyl]-3,4,5-trimethoxybenzoate 4-methyl-2H-chromen-2-on-7-yl sulphate, a drug comprising compound [2-(dimethylamino)-2-phenylbutyl]-3,4,5-trimethoxybenzoate 4-methyl-2H-chromen-2-on-7-yl sulphate, and a finished dosage form comprising compound [L-(dimethylamino)-2-phenybutyl ]-3,4,5 -trimethoxybenzoate 4-methyl-2H-chromen-2-on-7-yl sulphate. The invention further relates to the use of compound [2-(dimethylamino) phenylbutyl]-3,4,5-trimethoxy benzoate 4-methyl-2H-chromen-2-on-7-yl sulphate for treating and preventing functional gastrointestinal disorders.

Hyperthyroid diarrhea refers to hyperthyroid diarrhea, which is mostly intractable diarrhea, due to excessive thyroid hormone causing increased intestinal peristalsis excitability and diarrhea when the thyroid function is increased, which is caused by endocrine metabolic disorder leading to gastrointestinal function disorder. The present application studies and observes the treatment effect of kaempferol coupling derivative JC-1 on diarrhea of hyperthyroid model mice, and provides a new drug treatment option for diarrhea type colon dysfunction.

The invention relates to a preparation for treating acute plateau gastrointestinal dysfunction as well as a preparation method and application of the preparation, active ingredients in a pharmaceutical composition are extracted through a supercritical carbon dioxide fluid extraction technology on the basis of a formula for tonifying middle-Jiao and Qi, and a reagent or a reagent composition suitable for oral administration and / or patch is further prepared. The reagent or the reagent composition is suitable for gastrointestinal dysfunction caused by rapid plateau entry.

The invention relates to the technical field of medical treatment, in particular to gastrointestinal dysfunction treatment equipment based on awn needle therapy, which comprises a moving plate, a steering assembly is fixedly connected to the bottom of the moving plate, a working disc is fixedly connected to the bottom of the steering assembly, and a needle storage box is fixedly connected to the bottom of the working disc. And the top of the needle storage box is fixedly connected with a rotating motor. According to the gastrointestinal dysfunction treatment equipment based on the awn needle therapy, accurate positioning and intelligent operation are achieved, it is ensured that treatment is safe and efficient, the equipment detects the treatment part in real time through the scanner, and by combining with a multi-freedom-degree positioning system composed of a steering assembly, a working disc, a rotating motor and the like, acupuncture points can be accurately positioned. The awn needle is automatically taken, fixed and punctured by the telescopic rod I, the needle fixing sleeve and other parts, so that the dependence on the personal manipulation of an operator is greatly reduced, the personal error is avoided, the treatment process is standardized and precise, and the operation safety and the treatment efficiency are remarkably improved.

The present invention relates to compositions comprising a mix of human milk oligosaccharides consisting of 2′-fucosyllactose and difucosyllactose, for use in the reduction of pain and / or perception of pain in an infant or in a young child. The compositions are particularly effective in the restoration of the sensitivity of the bi-directional pain transmission pathways in the gut-brain axis to normal levels. The compositions are in particular useful in reducing abdominal pain, such as pain associated with gastrointestinal discomfort, functional gastrointestinal disorders, and / or gastrointestinal diseases and consequently also contribute to reducing the crying periods and to improving the quality of sleep, the general quality of life, the mood, the playfulness, the temperament and / or the happiness of the infants and young children.

Methods and systems for improving medical conditions by delivering a focused ultrasound signal to target sites of the autonomic nervous system. The focused ultrasound signal can have a mechanical index of between about 0.1 to about 5.0 and / or an acoustic pressure of between about 0.1 MPa to about 2.5 MPa. The medical condition can comprise chronic or refractory rhinitis, chronic rhinosinusitis, autonomic instability / autonomic dysfunction, functional gastrointestinal disorders, inflammatory disorders, immune disorders (including improving cancer and infections by neuromodulation of immune function), complex regional pain syndrome, post-traumatic stress disorder (PTSD), anxiety and anxiety-associated disorders, autism, fibromyalgia, uterine function, metabolic disorder, urinary incontinence or binge eating.

This application relates to the pharmaceutical field, and specifically to a multi-TRP ion channel modulator, its preparation method, and its application. The multi-TRP ion channel modulator developed in this application can inhibit TRPV1, activate TRPM8, and activate TRPA1, and can be used to treat functional gastrointestinal disorders, intestinal mucosal damage, intestinal inflammation, immune dysregulation, gut microbiota imbalance, gastrointestinal tumors, pain, or peripheral neuritis.

Compositions comprising a mixture comprising the bacterial strain Bifidobacterium bifidum MIMBb23sg or BbfIBS01 (DSM 32708), at least one or more bacterial strains selected from group A comprising the strains B. breve BbIBS01 (DSM 33231), B. breve BbIBS02 (DSM 33232), B. animalis subsp. lactis BlIBS01 (DSM 33233) and L. plantarum LpIBS01 (DSM 33234) and, optionally, at least one further bacterial strain selected from a bacterial strain L. casei DG® (CNCM I-1572) and a bacterial strain L. paracasei LPC-S01™ (DSM 26760) and related method for the treatment of gastrointestinal diseases, disorders or symptoms, in particular functional gastrointestinal disorders, such as, for example irritable bowel syndrome (IBS) are described.

This invention relates to the field of medical device technology. It comprises a housing, a connecting tube, a limiting mechanism, and a gastric tube fixing mechanism. Limiting mechanisms are fixed on both the front and rear sides of one outer wall of the housing. A connecting tube is inserted into the other side wall of the housing, and the gastric tube fixing mechanism is fitted onto the outer end of the connecting tube. A flow control valve is installed on the connecting tube and located inside the housing. A pump is fixed on the inner wall of one side of the housing. The outlet of the pump is connected to the connecting tube, and an inlet pipe is connected to the inlet of the pump. This invention facilitates the fixing of the gastric tube while controlling the injection speed, preventing a sudden increase in the infant's gastric contents and avoiding gastrointestinal dysfunction, thus reducing the occurrence of abdominal distension, vomiting, and other complications. This invention has the advantages of reasonable design and low manufacturing cost.

1. The name of the design product: biofeedback gastrointestinal medium frequency electric therapeutic instrument. 2. The use of the design product: for functional dyspepsia, postoperative intestinal paralysis and irritable bowel syndrome and other gastrointestinal functional disorder diseases. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

Methods and systems for improving medical conditions by delivering a focused ultrasound signal to target sites of the autonomic nervous system. The focused ultrasound signal can have a mechanical index of between about 0.1 to about 5.0 and / or an acoustic pressure of between about 0.1 MPa to about 2.5 MPa. The medical condition can comprise chronic or refractory rhinitis, chronic rhinosinusitis, autonomic instability / autonomic dysfunction, functional gastrointestinal disorders, inflammatory disorders, immune disorders (including improving cancer and infections by neuromodulation of immune function), complex regional pain syndrome, post-traumatic stress disorder (PTSD), anxiety and anxiety-associated disorders, autism, fibromyalgia, uterine function, metabolic disorder, urinary incontinence or binge eating.