Method for laser thrombolysis in blood vessel based on endoscopic guidance

Abstract

The invention provides a method for selectively utilizing 308nm and 2-micron lasers for thrombolysis in a blood vessel based on endoscopic guidance. Instruments applied to the method include an endoscopic imaging system, a 308nm excimer laser, a 2-micron laser and optical catheters. The endoscopic imaging system is used for observing thrombi in the blood vessel, determining components of the thrombi according to conditions of collected images and selecting different lasers for laser thrombolysis. The 308nm excimer laser is used for generating 308nm laser pulses which mainly act on non-calcified thrombi. The 2-micron laser is used for generating laser pulses in a 2-micron band, which are mainly used for eroding calcified thrombi. The optical catheters include an endoscope catheter, a 308nmlaser catheter and a 2-micron laser catheter which are connected to an endoscopic imaging device, the 308nm excimer laser and the 2-micron laser respectively. The optical catheters are used for real-time visual observation and elimination of the thrombi in the blood vessel. The method is simple in structure and convenient to operate, and has broad application prospect and high value in the field of laser thrombolysis.

Description

[0001] (1) Technical field [0002] The invention relates to a method for selectively utilizing 308nm and 2 micron lasers to perform visible thrombolysis under the guidance of an endoscope, in particular to the field of laser thrombolysis. [0003] (2) Background technology [0004] Since the 19th century, medical endoscopes have attracted extensive attention from medical workers and researchers because of their ability to visually observe internal lesions in patients. At present, the minimally invasive technology centered on the endoscopic system has been applied to many departments such as otolinology, general surgery, obstetrics and gynecology, thoracic surgery, and urology, involving everything from simple laparoscopic surgery to heart bypass. Among them, the vascular endoscope can enable clinicians to directly observe the three-dimensional images of the heart and blood vessels through non-surgical means, which greatly facilitates the diagnosis and treatment of cardiovascul...

AI Technical Summary

Problems solved by technology

However, the 308nm laser mainly acts on protein and fat, and cannot fragment calcified thrombus well

Compared with 308nm laser, 2 micron laser has stronger shock wave and tissue thermal effect, which can effectively fragment calcified thrombus, but excessive shock wave may cause side effects such as tissue stripping, intramural hemorrhage and even perforation, so set appropriate laser parameters Very important

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