Moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide and preparation method and application of moisturizing, anti-inflammatory and anti-wrinkle composition

A technology of ceramide and composition, which is applied in the field of moisturizing, anti-inflammatory and anti-wrinkle compositions, can solve the problems of easy crystallization and precipitation, and difficult application of water-based cosmetics, so as to avoid the phenomenon of Austenitic ripening, not easily affected by external factors, and improve the utilization rate Effect

Active Publication Date: 2019-08-16
广州科斯曼生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since ceramide is fat-soluble and easy to crystallize and precipitate, it is difficult to appl

Method used

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  • Moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide and preparation method and application of moisturizing, anti-inflammatory and anti-wrinkle composition
  • Moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide and preparation method and application of moisturizing, anti-inflammatory and anti-wrinkle composition
  • Moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide and preparation method and application of moisturizing, anti-inflammatory and anti-wrinkle composition

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0056] Example 1:

[0057] A moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide, the raw material composition of which is shown in the following table:

[0058] Table 1 Raw material composition table of a moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide

[0059]

[0060] The method for preparing the moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide includes the following steps:

[0061] 1) Mix the isomerized sugar, sodium stearyl glutamate, butylene glycol and water, heat to 85°C, stir evenly to obtain a mixed solution;

[0062] 2) Mix phosphatidylcholine, ceramide and phytosterol, heat to 85°C, stir evenly, and then ultrasonically disperse (the frequency of the ultrasonic disperser is 28kHz) to obtain a liquid mixture;

[0063] 3) Add the mixed solution of step 1) and the liquid mixture of step 2) into the homogenizer for homogenization (the speed of the homogenizer is 10000r / min), and then the ...

Example Embodiment

[0077] Example 2:

[0078] A moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide, the raw material composition of which is shown in the following table:

[0079] Table 3 Raw material composition table of a moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide

[0080]

[0081] The method for preparing the moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide includes the following steps:

[0082] 1) Mix the isomerized sugar, sodium stearyl glutamate, butylene glycol and water, heat to 85°C, stir evenly to obtain a mixed solution;

[0083] 2) Mix phosphatidylcholine, ceramide and phytosterol, heat to 85°C, stir evenly, and then ultrasonically disperse (the frequency of the ultrasonic disperser is 28kHz) to obtain a liquid mixture;

[0084] 3) Add the mixed solution of step 1) and the liquid mixture of step 2) into the homogenizer for homogenization (the speed of the homogenizer is 10000r / min), and then the ...

Example Embodiment

[0097] Example 3:

[0098] A moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide, the raw material composition of which is shown in the following table:

[0099] Table 5 Raw material composition table of a moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide

[0100]

[0101] The method for preparing the moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide includes the following steps:

[0102] 1) Mix the isomerized sugar, sodium stearyl glutamate, butylene glycol and water, heat to 85°C, stir evenly to obtain a mixed solution;

[0103] 2) Mix phosphatidylcholine, ceramide and phytosterol, heat to 85°C, stir evenly, and then ultrasonically disperse (the frequency of the ultrasonic disperser is 28kHz) to obtain a liquid mixture;

[0104] 3) Add the mixed solution of step 1) and the liquid mixture of step 2) into the homogenizer for homogenization (the speed of the homogenizer is 10000r / min), and then the ...

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Abstract

The invention discloses a moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide and a preparation method and application of the moisturizing, anti-inflammatory and anti-wrinkle composition. The composition is composed of isosaccharide, phosphatidylcholine, ceramide, plant sterol, stearyl glutamate, butylene glycol and water, and the phosphatidylcholine and the ceramide form a sheath phospholipid structure. The preparation method includes the steps of 1), preparing a mixed solution of isosaccharide, stearyl glutamate and butylene glycol; 2), preparing a liquid mixtureof isosaccharide, ceramide and plant sterol; 3), subjecting the mixed solution in the step 1) and the liquid mixture in the step 2) to homogeneity, microjet treatment and filtration. The compositionhas excellent moisturizing, anti-inflammatory and anti-wrinkle effect, and is easy to absorb through a film; the composition is added to transparent water-based cosmetics with transparent appearance,long-term stability and no stratification and turbidity; the composition is simple in preparation process and can be produced on a large scale.

Description

technical field [0001] The invention relates to a moisturizing, anti-inflammatory and anti-wrinkle composition containing ceramide, a preparation method and application thereof. Background technique [0002] The barrier function of the skin is mainly provided by the stratum corneum, the outermost layer of the skin. The stratum corneum has a structure similar to a brick wall. Keratinocytes (flat cells without nuclei) are "bricks" embedded in lipid "cement". It is mainly composed of ceramide, cholesterol and fatty acid. The proportion of ceramide in the horny sebum is 40%-50%, which can make the intercellular lipids in the stratum corneum form a multilayer lamination structure, and further form a high-viscosity two-way lipid layer to prevent or reduce transdermal The effect of water loss. The reduction of ceramide will directly affect the skin barrier function, resulting in increased skin water loss and easier invasion of external harmful substances, eventually causing dry a...

Claims

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Application Information

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IPC IPC(8): A61K8/68A61K8/63A61K8/60A61K8/55A61K8/34A61K8/44A61P29/00A61Q19/00A61Q19/08
CPCA61K8/345A61K8/44A61K8/55A61K8/60A61K8/63A61K8/68A61K2800/413A61Q19/00A61Q19/08A61P29/00
Inventor 庄福平
Owner 广州科斯曼生物科技有限公司
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