Composition of isomaltooligosaccharide and calcium ion antagonist as well as application thereof

A calcium ion antagonist and isomalt oligosaccharide technology, which is applied in the field of the composition of isomalt oligosaccharide and calcium ion antagonist, can solve the problem of increased osmotic pressure, does not involve the direct interaction between IMO and intestinal mucosal cells, etc. problem, to achieve a good application prospect, to solve the effect of constipation side effects
CN110152002AInactive Publication Date: 2019-08-23LUDONG UNIVERSITY
2 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
LUDONG UNIVERSITY
Publication Date
2019-08-23
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a composition of isomaltooligosaccharide and a calcium ion antagonist. According to the composition, the isomaltooligosaccharide which is not absorbed by an intestinal tract can be used for relieving the constipation side effect generated by use of hypotensive medicines while the calcium ion antagonist reduces pressure. The invention belongs to the fields of the composition of the isomaltooligosaccharide and the calcium ion antagonist as well as application thereof. In the composition of the isomaltooligosaccharide and the calcium ion antagonist, the mass ratio of theisomaltooligosaccharide to the calcium ion antagonist is 10:1 to 1:1. The composition of the isomaltooligosaccharide and the calcium ion antagonist can solve the problem of the constipation side effect generated by long-time use of the calcium ion antagonist, can discloses the newest action mechanism of the action, can provide the optimal combined proportion of the isomaltooligosaccharide and thecalcium ion antagonist, and has good application prospect.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a composition of isomaltose oligosaccharide and calcium ion antagonist, which can alleviate the constipation caused by taking antihypertensive drugs while lowering blood pressure, and belongs to the composition of isomaltooligosaccharide and calcium ion antagonist and its technical fields of application. Background technique

[0002] Calcium ion antagonists such as nifedipine, amlodipine, and felodipine are commonly used "dipine" antihypertensive drugs, which belong to one of the five categories of drugs recommended in the "Guidelines for the Prevention and Treatment of Hypertension in China" in 2018 . Calcium ion antagonists such as nifedipine can prevent calcium ions from entering the myocardium or vascular smooth muscle cells, causing a decrease in the tension of blood vessels around the body and coronary arteries, resulting in a decrease in blood pressure and an increase in coronary blood flow. Some patients may experienc...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More