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Enhanced Anti-Hair Loss Growth Composition

A technology for preventing hair loss and regenerating, the composition is applied in the directions of drug combination, hair care, medical preparations containing active ingredients, etc., and can solve the problems of high surgical treatment cost, drug dependence, side effects and the like

Active Publication Date: 2022-08-02
NATURAL MEDICINE INST OF ZHEJIANG YANGSHENGTANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Drug treatment mainly includes finasteride and minoxidil, which often have serious side effects and are prone to drug dependence. Once the drug is stopped, hair loss will be more serious; surgical treatment is expensive, traumatic, and requires a certain recovery period

Method used

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  • Enhanced Anti-Hair Loss Growth Composition
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  • Enhanced Anti-Hair Loss Growth Composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1 : Inhibition of 5α-reductase activity

[0031] In this example, different times of concentrated birch sap, ginger extract, Polygonum multiflorum root extract, ginseng extract, green tea extract, oriental orientalis extract, and their compositions on 5α-reductase activity were investigated and compared. Impact.

[0032] 1. Concentration of birch sap

[0033] The fresh birch sap stock solution purchased from Daxinganling Chaoyue Wild Berry Development Co., Ltd. was input into the low-temperature drying equipment, cooled to -65°C, evacuated to 0.1Pa, and concentrated 1.5 and 10 times.

[0034] 2. Test

[0035] Experimental equipment: balance, wall breaker, constant temperature oscillator, high-speed refrigerated centrifuge, microplate reader.

[0036] Experimental reagents and consumables:

[0037] Finasteride: Shanghai Modern Pharmaceutical Co., Ltd. (tablet 5mg / tablet);

[0038] Reduced coenzyme II (NADPH): American Roche company (powder 10mg);

[0039] ...

Embodiment 2

[0060] Example 2 : Effects on the expression of genes and proteins related to hair loss prevention

[0061] In this example, the effects of different multiples of concentrated birch sap, angelica extract, astragalus, eucalyptus, birch bud extract, birch leaf extract, and their compositions on anti-hair loss and growth-related genes were investigated and compared. effect on protein expression.

[0062] 1. Concentration of birch sap

[0063] The fresh birch sap stock solution purchased from Daxinganling Chaoyue Wild Berry Development Co., Ltd. was input into the low-temperature drying equipment, cooled to -65°C, evacuated to 0.1Pa, and concentrated 1.5 and 10 times.

[0064] 2. Test

[0065] The dermal papilla cells used in this experiment were produced by Guangdong Boxi Biotechnology Co., Ltd.

[0066] Experimental instrument: CO 2 Incubator (Thermo), ultra-clean workbench (Sujing Antai), inverted microscope (Olympus), micro shaker (Qilin Bell), microplate reader (BioTek)...

Embodiment 3

[0086] Example 3 : Effects on proliferation and differentiation of dermal papilla cells

[0087] In this example, the effects of different times of concentrated birch sap, adenosine, nicotinamide, copper tripeptide-1, and their combinations on the proliferation and differentiation ability of dermal papilla cells were investigated and compared.

[0088] 1. Concentration of birch sap

[0089] The fresh birch sap stock solution purchased from Daxinganling Chaoyue Wild Berry Development Co., Ltd. was input into the low-temperature drying equipment, cooled to -65°C, evacuated to 0.1Pa, and concentrated 1.5 and 10 times.

[0090] 2. Test method

[0091] The dermal papilla cells used in this experiment were produced by Guangdong Boxi Biotechnology Co., Ltd.

[0092] Experimental instrument: CO 2 Incubator (Thermo), ultra-clean workbench (Sujing Antai), inverted microscope (Olympus), micro shaker (Qilin Bell), microplate reader (BioTek), incubator (Tester).

[0093] Experimental...

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Abstract

The present invention provides an enhanced hair loss prevention composition comprising (A) concentrated birch sap and (B) ginger extract, Polygonum multiflorum root extract, ginseng extract, green tea extract, oriental orientalis extract, angelica extract The combination of any one or more of the extract, Astragalus, Ecclusa, birch bud extract, birch leaf extract, adenosine, nicotinamide, tripeptide-1 copper, wherein the concentration multiple of the concentrated birch sap It is about 1.2-8 times, preferably about 1.5-6 times, more preferably about 1.5-5 times.

Description

technical field [0001] The present invention relates to an enhanced hair loss prevention composition comprising (A) concentrated birch sap and (B) ginger extract, Polygonum multiflorum root extract, ginseng extract, green tea extract, oriental orientalis extract, angelica extract A combination of any one or more of the herb, Astragalus, Eclipta, birch bud extract, birch leaf extract, adenosine, nicotinamide, tripeptide-1 copper, wherein the concentration multiple of the concentrated birch sap It is about 1.2-8 times, preferably about 1.5-6 times, more preferably about 1.5-5 times. Background technique [0002] With the accelerated pace of life in modern society and the deteriorating environment, more and more people are suffering from sub-health problems of varying degrees under the conditions of high-intensity mental stress, overtime, staying up late, and smog. This brings about problems such as increased scalp oil secretion, scalp inflammation, hair follicle atrophy, and ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/9794A61K8/9761A61K8/67A61K8/64A61K8/49A61Q5/02A61Q7/00A61P17/14
CPCA61K8/9789A61K8/9794A61K8/9761A61K8/4973A61K8/675A61K8/64A61Q5/02A61Q7/00A61P17/14A61K2800/782
Inventor 赵瑞丽王莎莎
Owner NATURAL MEDICINE INST OF ZHEJIANG YANGSHENGTANG