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Emblic leafflower fruit extract capable of dispelling effects of alcohol and protecting liver as well as preparation method and application thereof

A technology for relieving hangover and protecting the liver and embola, applied in the directions of food ingredients, application, and food science containing natural extracts, can solve problems such as differences in efficacy, and achieve a reduction in AST content, high active ingredient content, and simple and reasonable beverage formulations. Effect

Inactive Publication Date: 2020-04-17
GUANGDONG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Emblica (Phyllanthus emblica L.) is a Phyllanthus emblica plant in the Euphorbiaceae family. Phyllanthus emblica L. is rich in active substances such as superoxide dismutase, vitamin C, polyphenols and polysaccharides. In addition to having strong antioxidant activity , also has anti-inflammation, anti-influenza, anti-hypertension, anti-tumor, liver protection and other effects. At present, the extraction of emblica mainly uses solvent extraction method. Due to the different solvents used and the differences in subsequent purification procedures, the preparation of The active ingredients of the obtained emblica extracts are not the same, and there are large differences in their efficacy.

Method used

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  • Emblic leafflower fruit extract capable of dispelling effects of alcohol and protecting liver as well as preparation method and application thereof
  • Emblic leafflower fruit extract capable of dispelling effects of alcohol and protecting liver as well as preparation method and application thereof
  • Emblic leafflower fruit extract capable of dispelling effects of alcohol and protecting liver as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Embodiment 1 (ethyl acetate extraction)

[0065] (1) fresh Emlical emblica is washed, cored and dried, then pulverized and passed through a 60-mesh sieve to obtain Emlical emblica micropowder;

[0066] (2) Add 80 mass multiples of water to the emblica micropowder prepared in step (1), extract at 80° C. for 10 minutes; then centrifuge at 4000 r / min for 10 minutes to obtain the emblica extract;

[0067] (3) Concentrate the emblica extract obtained in step (2), then add water to redissolve it; then add ethyl acetate equal to the volume of water for extraction, and collect the extract phase; further concentrate the extract phase to obtain anti-alcohol and liver-protecting Amla Extract.

Embodiment 2

[0068] Embodiment 2 (ethyl acetate extraction)

[0069] (1) fresh Emlical emblica is washed, cored and dried, then pulverized and passed through a 40-mesh sieve to obtain Micro-powder of Emlical emblica;

[0070] (2) Add water of 90 mass multiples to the emblica micropowder prepared in step (1), extract at 70° C. for 15 minutes; then centrifuge at 3000 r / min for 15 minutes to obtain the emblica extract;

[0071] (3) Concentrate the emblica extract obtained in step (2), then add water to redissolve it; then add ethyl acetate equal to the volume of water for extraction, and collect the extract phase; further concentrate the extract phase to obtain anti-alcohol and liver-protecting Amla Extract.

Embodiment 3

[0072] Embodiment 3 (ethyl acetate extraction)

[0073] (1) fresh Emlical emblica is cleaned, cored and dried, then pulverized and passed through an 80-mesh sieve to obtain Emlical emblica micropowder;

[0074] (2) Add 60 mass multiples of water to the emblica micropowder prepared in step (1), and extract at 90° C. for 8 minutes; then centrifuge at 5000 r / min for 6 minutes to obtain the emblica extract;

[0075] (3) Concentrate the emblica extract obtained in step (2), then add water to redissolve it; then add ethyl acetate equal to the volume of water for extraction, and collect the extract phase; further concentrate the extract phase to obtain anti-alcohol and liver-protecting Amla Extract.

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Abstract

The invention belongs to the technical field of plant extraction, and particularly relates to an emblic leafflower fruit extract capable of dispelling the effects of alcohol and protecting the liver as well as a preparation method and application thereof. The preparation method comprises the following steps: cleaning fresh emblic leafflower fruits, denucleating and drying the fresh emblic leafflower fruits, crushing the fresh emblic leafflower fruits, carrying out sieving to obtain emblic leafflower fruit micro-powder, adding water, carrying out extracting at 70-90 DEG C for 8-15 minutes, carrying out centrifuging to obtain an emblic leafflower fruit extracting solution, further concentrating the emblic leafflower fruit extracting solution, and adding water for re-dissolving; adding ethylacetate for extraction, and collecting an extraction phase; and further concentrating the extract phase to obtain the emblic leafflower fruit extract capable of dispelling the effects of alcohol and protecting the liver. The main components of the extract are gallic acid, corilagin and ellagic acid, wherein the content of gallic acid is the highest and reaches 2.42mg / g, gallic acid has a good inhibition effect on BRL-3A alcoholic injury, that is, gallic acid has a good protection effect on BRL-3A cells with alcoholic injury, and the damage of alcohol to the liver is further reduced by increasing the SOD content and reducing the MDA content, the ALT content and the AST content.

Description

technical field [0001] The invention belongs to the technical field of plant extraction, and in particular relates to an extract of emblica emblica for hangover and liver protection, as well as its preparation method and application. Background technique [0002] Alcohol has become a special drink that is difficult for most people to quit. Unscientific drinking will bring harm to people's health, and it will do the most damage to the liver. Most of the anti-alcoholic medicines on the market are to relieve the temporary discomfort of the body, but cannot relieve the damage of alcohol to the liver. As the so-called three-point poison of the medicine, regular use will not only bring some toxic side effects, but also lead to dependence on the medicine. With the gradual improvement of people's health awareness, most people now pay attention to health preservation and diet therapy. Therefore, it has become a demand in the market to develop anti-alcoholic and liver-protecting produ...

Claims

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Application Information

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IPC IPC(8): A23L2/38A23L2/52A23L2/60A23L2/74A23L2/76A23L2/46A23L33/105
CPCA23L2/38A23L2/52A23L2/60A23L2/74A23L2/76A23L2/46A23L33/105A23V2002/00A23V2200/30A23V2200/14A23V2250/21
Inventor 刘晓丽杨冰鑫陈柳青林沛
Owner GUANGDONG UNIV OF TECH
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