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Vaporization system for delivery in a controlled concentration

A concentration, subject technique, applied in therapeutic nebulizers, inorganic chemistry, nitrogen compounds, etc.

Active Publication Date: 2020-05-22
CASE WESTERN RESERVE UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Typically, a large ENO gas tank is required to deliver the ENO gas to the subject, and the tank cannot be easily moved by the subject receiving the ENO gas

Method used

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  • Vaporization system for delivery in a controlled concentration
  • Vaporization system for delivery in a controlled concentration
  • Vaporization system for delivery in a controlled concentration

Examples

Experimental program
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Embodiment Construction

[0041] The embodiments disclosed below are not intended to be exhaustive or to limit the scope of the present disclosure to the precise forms described below. Rather, the embodiments were chosen and described as examples so that others skilled in the art can utilize their teachings.

[0042] Unless otherwise stated, as used herein, the term "about" refers to a range of value within ±10% of the specified value. For example, the phrase "about 200" includes 200 ± 10%, or from 180 to 220. When stated otherwise, the term "about" refers to a range of values ​​including ±20%, ±10%, or ±5% and the like.

[0043] figure 1 A schematic diagram of an embodiment of an ambulatory device 100 for delivering controlled concentrations of substances is shown in . In some embodiments, a device can be used to deliver a nitrosating agent to a subject. Nitrosating agents include, but are not limited to, the following: ethyl nitrite, amyl nitrite, butyl nitrite, isobutyl nitrite, t-butyl nitrite,...

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Abstract

Devices for delivering a controlled concentration of an agent are provided. The device includes a reservoir for the agent and a flow control portion operably connected to the reservoir. The device also includes a valve for releasing the agent from the flow control portion and a pump for flowing air to mix with the agent released by the valve and for flowing the agent and air mixture out of the device. Methods of delivering a vaporized agent to a subject are also provided. The methods include storing a liquid agent in a reservoir of a device and flowing the agent into a flow control chamber tochange the agent to a gas. The methods also include mixing the agent in gas form with air and flowing the agent and air mixture out of the device to be delivered to a subject.

Description

[0001] related application [0002] Pursuant to Title 35, United States Code, Section 119(e), this application claims the benefit and priority of U.S. Provisional Application No. 62 / 516,973, filed June 8, 2017, the entire contents of which are hereby incorporated by reference in their entirety . [0003] Federally funded research or development [0004] This invention was made with Government support under Federal Grant No. N66001-10-C-2015 awarded by the Defense Advanced Research Projects Agency. The government has certain rights in this invention. technical field [0005] The present application relates to devices and methods for delivering controlled concentrations of substances using vaporization systems, and more particularly to devices and methods for ambulatory vaporization systems for delivering nitrosating agents. Background technique [0006] Currently, the administration of ethyl nitrite (ENO) gas is cumbersome and not suitable for ambulatory care. Typically, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M16/00A61M16/01A61M16/10A61M16/12A61M16/20A61M11/04C01B21/20A61M16/06
CPCA61M16/125A61M16/1075A61M16/204A61M16/109A61M16/0066A61M16/024A61M11/042A61M16/022A61M16/0666A61M16/0069A61M16/01A61M16/0057A61M2202/0275A61M2202/0266A61M2205/3673A61M2205/3368A61M2205/8206A61M2205/3334A61M2205/3331A61M2202/02A61M2202/03A61M2205/50A61M2205/3606A61M2016/0015A61M2202/0007
Inventor 乔纳森·S·斯坦勒
Owner CASE WESTERN RESERVE UNIV