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Cynanchum otophyllum schneid and radix gentianae twitch-relieving granules

A technology of gentian and Qingyang ginseng, which is applied in the direction of medical raw materials derived from ferns/filamentous plants, plant raw materials, nervous system diseases, etc., and can solve problems such as ineffective efficacy

Active Publication Date: 2020-09-04
YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, through clinical comparison, the efficacy of the above composition is not obvious

Method used

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  • Cynanchum otophyllum schneid and radix gentianae twitch-relieving granules
  • Cynanchum otophyllum schneid and radix gentianae twitch-relieving granules
  • Cynanchum otophyllum schneid and radix gentianae twitch-relieving granules

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Embodiment 1 clinical trial

[0078] Qinglongzhizhifang is the sixth batch of national veteran traditional Chinese medicine experts' academic experience inheritance work instructor Professor Xiong Lei's clinical efficacy prescription. , Uncaria, Shichangpu and Shenjincao and other nine traditional Chinese medicines. It is clinically used in the treatment of children with TS and other excitatory movement disorders. From April 2019 to January 2020, we treated a total of 32 TS patients, including 25 boys and 7 girls. The Yale General Tournament Severity Scale (YGTSS) and the TCM Syndrome Rating Scale were used to evaluate the He made an assessment, and continued to treat with Qinglong Zhizhi Fang for 8 weeks, taking 3 times a day for 2 days per payment. After 8 weeks, the Yale Composite Tournament Severity Scale score in children with TS ( figure 1 ) and TCM syndrome score ( figure 2 ) were significantly reduced, proving that their tic symptoms have been significantly...

Embodiment 2

[0084] Preparation of Qinglong Zhizhi Granules

[0085] (1) Prescription

[0086]

[0087] (2) Preparation

[0088] The above-mentioned nine herbs are pulverized, decocted twice with water for 2 hours each time, concentrated, dried, pulverized, mixed with sucrose and dextrin, made into granules, dried, and prepared.

Embodiment 3

[0090] Preparation of Qinglong Zhizhi Tablets

[0091] (1) Prescription

[0092]

[0093] (2) Preparation

[0094] The above-mentioned nine herbs are pulverized, decocted twice with water for 2 hours each time, concentrated, dried, pulverized, mixed with sucrose and dextrin, made into granules, dried, and pressed into tablets to obtain the product.

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Abstract

The invention relates to cynanchum otophyllum schneid and radix gentianae twitch-relieving granules, and provides a traditional Chinese medicine composition for treating the pediatric tourette syndrome. The granules comprise the following raw materials: 2-20 g of cynanchum otophyllum schneid, 1-10 g of radix gentianae, 2-20 g of radix stellariae, 3-30 g of radix paeoniae alba, 3-30 g of rhizoma gastrodiae, 3-30 g of ramulus uncariae cum uncis, 2-20 g of rhizoma acori graminei, 2-20 g of merremia hungaiensis and 2-20 g of herba lycopodii. The granules are used for treating TS and other excitatory dyskinesia of children, have a remarkable curative effect, can effectively invigorate the spleen, reduce phlegm, calm the liver, calm endogenous wind, soothe the nerves and promote intelligence inpractice of traditional Chinese medicine therapy, provide nutrition for the brain and exert the effects of restoring consciousness and tranquilizing mind, so that the twitch symptom is relieved.

Description

technical field [0001] The application relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating children with multiple tics. Background technique [0002] The main clinical symptoms of TS in children are rapid motor muscle twitches, such as blinking, pouting, frowning, nodding, head shaking, neck twisting, shrugging, arm raising, kicking, belly distension, etc. Laryngeal muscle twitches can manifest as Throat clearing, screaming, and even foul language are often accompanied by mental and psychological problems such as bad temper, lack of concentration, loneliness, depression, and low self-esteem. At present, there is no specific specific drug in the treatment of TS in Western medicine. Compared with western medicine, traditional Chinese medicine has multi-level, multi-target, and multi-link effects in treating TS. It can regulate the balance of yin and yang and viscera functions in children, and comprehe...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61K9/16A61P25/00
CPCA61K36/27A61K36/515A61K36/36A61K36/71A61K36/65A61K36/8988A61K36/74A61K36/888A61K36/39A61K36/11A61K9/1652A61K9/1623A61P25/00A61K2236/331A61K2236/39A61K2300/00
Inventor 熊磊王纳秦冬冬吴忻晨王丁越解宇环赵毅
Owner YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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