Bacteriostatic mesoporous silicon dioxide compound as well as preparation method and application thereof

A technology of mesoporous silica and silica, applied in the field of composites, can solve problems such as skin sensitivity, and achieve the effect of solving skin sensitivity and excellent antibacterial materials

Active Publication Date: 2020-11-17
ZHONGKAI UNIV OF AGRI & ENG +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

A small amount of TTO is not irritating to the skin, but excessive use can cause skin sensitivity

Method used

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  • Bacteriostatic mesoporous silicon dioxide compound as well as preparation method and application thereof
  • Bacteriostatic mesoporous silicon dioxide compound as well as preparation method and application thereof
  • Bacteriostatic mesoporous silicon dioxide compound as well as preparation method and application thereof

Examples

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preparation example Construction

[0057] The preparation method of SBA-16 in Examples 9 to 14 is as follows: take triblock copolymer F127 and a hydrochloric acid solution with a concentration of 1.8-2.2 mol / L into a container, stir and dissolve template agent F127 at 40 ° C, and then use constant Press the funnel to slowly add TEOS dropwise to the above container, continue stirring for 24h, then transfer the solution to the reaction kettle, crystallize at 100°C for 48h, cool, filter with suction, wash until neutral, and blow dry at 100°C to obtain a solution that does not release the template agent. SBA-16. The SBA-16 prepared above was wrapped with filter paper, placed in a Soxhlet extractor, and the template agent in the mesoporous SBA-16 was refluxed with 2.5% hydrochloric acid-ethanol solution. After reflux extraction for 72 hours, the sample was extracted. Washed with water until neutral, dried to constant weight in a blast drying oven at 100°C to obtain SBA-16.

[0058] Table 4 The addition amount of ea...

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Abstract

The invention discloses a bacteriostatic mesoporous silicon dioxide compound as well as a preparation method and application thereof, and belongs to the technical field of compounds. The mesoporous silicon dioxide compound comprises a carrier and a load, wherein the carrier comprises aminated mesoporous silicon dioxide modified by a rosin derivative; and the load comprises essential oil. The preparation method comprises the following steps of modifying the aminated mesoporous silicon dioxide by the rosin derivative in a physical or chemical manner to prepare the carrier having antibacterial properties, and then performing loading with any one of tea tree essential oil, peppermint essential oil or eugenol. The prepared mesoporous silicon dioxide compound shows excellent antibacterial properties and has relatively long antibacterial time.

Description

technical field [0001] The invention belongs to the technical field of composites, and in particular relates to a bacteriostatic mesoporous silica composite and a preparation method and application thereof. Background technique [0002] As an ordered mesoporous material, mesoporous silica has large pore volume, uniform pore size, high specific surface area and large adsorption capacity. Therefore, many scientists have studied it and used it to load various drugs and precisely control the release of drugs. At present, certain results have been achieved in the field of medicine. However, the research on mesoporous silica as a non-pharmaceutical carrier is very limited. [0003] Rosin, as a green and pollution-free forest resource, chemical modification of its structure to develop chemical products has become a research hotspot today. The study found that rosin derivatives have many biological activities in agriculture, such as weeding, insecticidal, antiseptic and bactericid...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/25A61K8/36A61K8/92A61Q17/00
CPCA61K8/25A61K8/36A61K8/922A61Q17/005A61K2800/72Y02A50/30
Inventor 周红军刘光华周新华高凡梁智均
Owner ZHONGKAI UNIV OF AGRI & ENG
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