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Application of traditional Chinese medicine composition in preparation of blood fat reducing medicine

A technology for hypolipidemic drugs and compositions, which can be applied to drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve problems such as general effects and adverse reactions, and achieve the effects of small adverse reactions and reasonable compatibility.

Inactive Publication Date: 2021-01-19
SHIJIAZHUANG YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

5. Drug treatment, the main drugs to lower serum triglycerides are fibrates and nicotinic acid, but these drugs have different degrees of adverse reactions
There are many Chinese patent medicines with blood lipid-lowering effect, but the effect is mediocre. The market urgently needs a Chinese medicine preparation with definite blood-lipid-lowering effect and few side effects.

Method used

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  • Application of traditional Chinese medicine composition in preparation of blood fat reducing medicine
  • Application of traditional Chinese medicine composition in preparation of blood fat reducing medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] The raw material medicine formula is: jujube 30g, mulberry 30g, ganoderma lucidum 10g, lily 5g, hawthorn 10g, poria cocos 5g, tangerine peel 5g chrysanthemum 10g, lotus leaf 5g;

[0048] Preparation:

[0049] (1) Take Chinese medicinal materials according to the prescription amount, and select them;

[0050] (2) Mix the above net-selected medicinal materials, make coarse powder, add 9 times the amount of water, soak for 1 hour, heat and decoct 2 times, the first time is 1.5 hours, the second time is 1 hour, filter, combine the filtrate, reduce Concentrate under pressure to 60°C to a clear paste with a relative density of 1.20-1.25 during heat measurement, add 95% ethanol to adjust the concentration to 75%, let it stand below 4°C for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell. Concentrate to a liquid extract with a relative density of 1.02-1.06 when thermally measured at 60°C, and set aside;

[0051]...

Embodiment 2

[0053] The formula of the raw material medicine is: jujube 36g, mulberry 36g, ganoderma lucidum 10g, lily 6g, hawthorn 12g, poria cocos 6g, tangerine peel 6g, chrysanthemum 12g, lotus leaf 6g

[0054] Preparation:

[0055] (1) Take Chinese medicinal materials according to the prescription amount, and select them;

[0056] (2) Mix the above net-selected medicinal materials, make coarse powder, add 9 times the amount of water, soak for 1 hour, heat and decoct 2 times, the first time is 1.5 hours, the second time is 1 hour, filter, combine the filtrate, reduce Concentrate under pressure to 60°C to a clear paste with a relative density of 1.20-1.25 during heat measurement, add 95% ethanol to adjust the concentration to 75%, let it stand below 4°C for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell. Concentrate to a liquid extract with a relative density of 1.02-1.06 when thermally measured at 60°C, and set aside;

...

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PUM

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Abstract

The invention provides application of a traditional Chinese medicine composition in preparation of a blood fat reducing medicine. The medicine is prepared from the following raw materials in parts byweight: 6-36 parts of wild jujube, 6-36 parts of mulberry, 2-12 parts of lucid ganoderma, 1-6 parts of lily, 2-12 parts of hawthorn, 1-6 parts of poria cocos, 1-6 parts of pericarpium citri reticulatae, 2-12 parts of chrysanthemum and 1-6 parts of lotus leaf. The traditional Chinese medicine composition has a good effect on reducing blood fat. The traditional Chinese medicine composition is reasonable in compatibility, simple and feasible, is a pure traditional Chinese medicine preparation, is small in adverse reaction and can be used by patients for a long time.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to an application of a traditional Chinese medicine composition in the preparation of blood lipid-lowering drugs. Background technique [0002] Blood lipids are the general term for neutral fats (triglycerides) and lipids (phospholipids, glycolipids, sterols, steroids) in plasma, which are widely present in the human body. They are essential substances for the basic metabolism of living cells. Generally speaking, the main components of blood lipids are triglycerides and cholesterol, of which triglycerides participate in energy metabolism in the human body, while cholesterol is mainly used for the synthesis of cell membranes, steroid hormones and bile acids. Hyperlipidemia refers to the concentration of blood lipid components such as plasma cholesterol, triglycerides, and total lipids exceeding the normal standard. The main hazard is to cause atheros...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8967A61P3/06
CPCA61K36/725A61K36/605A61K36/074A61K36/8967A61K36/734A61K36/076A61K36/752A61K36/287A61K36/62A61P3/06A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 吴以岭吴相君吴瑞贾振华
Owner SHIJIAZHUANG YILING PHARMA
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