Antipyretic heat-clearing traditional Chinese medicine mixture with epidemic cold treating effect, preparation method and use

A technology for mixture and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine, can solve the problems of not being easy to carry, time-consuming and laborious for decoction decoction, and not being able to be stored for a long time.

Inactive Publication Date: 2021-02-19
云南省中医医院
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, most Chinese medicine practitioners take oral Chinese medicine decoctions to prevent and treat TCM epidemics (epidemic colds), but the decoctions have the disadvantages of time-consuming and laborious decoction, large doses, not easy to carry, and cannot be stored for a long time, which affects the m

Method used

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  • Antipyretic heat-clearing traditional Chinese medicine mixture with epidemic cold treating effect, preparation method and use
  • Antipyretic heat-clearing traditional Chinese medicine mixture with epidemic cold treating effect, preparation method and use
  • Antipyretic heat-clearing traditional Chinese medicine mixture with epidemic cold treating effect, preparation method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Example 1: The clinical curative effect of Qingwen Jiere Mixture combined with western medicine on patients with mild to moderate COVID-19 is better than that of pure western medicine

[0044] Prescription: the Chinese medicine component of following weight part is included in Qingwenjiere mixture: the preparation method of described Qingwenjiere mixture comprises the steps:

[0045] (1) Take 10 parts of patchouli, 14 parts of Bupleurum, 7 parts of Scutellaria baicalensis, 9 parts of forsythia, 8 parts of French pinellia, 9 parts of fried Magnolia officinalis, 3 parts of Tsao Guo (broken and added), Bai Wei 9 parts, 9 parts of capillary, 8 parts of horseshoe incense, 6 parts of talc, 13 parts of fried divine song, 6 parts of licorice.

[0046] (2) For the first time, add water to 10 times the amount of medicinal materials, soak in cold water for 30 minutes, boil at normal pressure for 60 minutes, filter the medicinal solution through a 60-mesh filter; add water to 8 tim...

Embodiment 2

[0071]Embodiment 2 (prescription is the same as Embodiment 1): Qingwen Jiere Recipe is used to treat seasonal epidemic cold (damp-heat syndrome due to exogenous pathogenic factors)

[0072] In the Emergency Department of the First Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, from February 11, 2020 to March 1, 2020, Qingwen Jiere Recipe was clinically applied to 11 patients with seasonal epidemic cold (exogenous damp-heat syndrome), aged 48.73±16.32 years old, There were 9 males and 2 females. The average medication time was 3.13±1.24 days. The clinical efficacy is shown in Table 4. From Table 4, it can be seen that Qingwen Jiere Formula has a good antipyretic effect (the initial body temperature is 37.90±0.74°C, and the body temperature after taking the medicine is 36.37°C. ±0.12℃), can effectively reduce the degree of cough in patients, shorten the course of cough, and can effectively improve the patient's TCM clinical syndrome (the TCM syndrome sc...

Embodiment 3

[0075] Example 3 (prescription is the same as in Example 1): Qingwenjiere Mixture Mouse Acute Toxicity Experiment Pre-experimental Study No mouse poisoning and death

[0076] Kunming mice were given a single intragastric administration within 24 hours, the maximum volume of administration was 0.4ml / 10g, and the administration doses of the high and medium dose groups were: 116.3g / kg, 24g / kg, among which the high dose group was available Based on the dose of the maximum concentration of gavage (1500g stock solution is concentrated to 309.5g), the medium dose is the dose of the original drug solution concentration multiplied by the maximum administration volume. Observe and record the death and poisoning performance of each mouse within 14 days after administration. The result is as follows:

[0077] High-dose group: a total of 10 animals were administered, including 5 males and 5 females. On the day of administration, the autonomous activities of individual animals decreased s...

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Abstract

The invention relates to an antipyretic heat-clearing traditional Chinese medicine mixture with an epidemic cold treating effect, a preparation method and use and belongs to the field of traditional Chinese medicine compound preparations. The antipyretic heat-clearing traditional Chinese medicine mixture comprises the following traditional Chinese medicine ingredients in parts by weight: 10-11 parts of Pogostemon cablin, 12-14 parts of radix bupleuri, 7-9 parts of radix scutellariae, 7-9 parts of fructus forsythiae, 8-10 parts of prepared pinellia tubers, 6-9 parts of cortex magnoliae officinalis (parched), 3-5 parts of fructus amomi (crushed and decocted later), 9-12 parts of radix cynanchi atrati, 9-12 parts of herba artemisiae, 8-10 parts of Henry saruma, 6-10 parts of talcum, 10-13 parts of Massa medicata fermentata (parched) and 4-6 parts of radix glycyrrhizae. The whole prescription together exerts the effects of clearing away heat and eliminating dampness, perfuming and avoidingdirty and drying dampness to stop diarrhea. When the antipyretic heat-clearing traditional Chinese medicine mixture is applied to epidemic cold with manifestations of fever bodily pain, pharyngalgiacough, abdominal distention feeling of fullness, sticky, greasy, smelly and filthy feces or soft stool diarrhea, anorexia asthenia and the like, the antipyretic heat-clearing traditional Chinese medicine mixture has the effects of clearing away heat and eliminating dampness, perfuming and avoiding dirty and drying dampness to stop diarrhea and also has a certain treatment effect on novel coronavirus pneumonia in a novel coronavirus epidemic situation.

Description

technical field [0001] The present invention relates to the field of traditional Chinese medicine, in particular to a Qingwenjiere traditional Chinese medicine mixture for treating epidemic cold, its preparation method and application. Cough, abdominal distension, fullness, sticky and smelly stools or loose stools, diarrhea, anorexia and fatigue, etc. It has the effects of clearing away heat and dampness, fragrant and filthy, drying dampness and stopping diarrhea. It also has a certain effect on the new coronavirus pneumonia during the new crown epidemic. curative effect. Background technique [0002] With the changes in the social environment, human production and lifestyle, the increase in the flow of people at home and abroad, and the changes in the epidemic spectrum of diseases, various new and reappearing infectious diseases are still emerging, and they are spreading and epidemic around the world. It is still an important disease that seriously threatens human health. ...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61K9/00A61P1/12A61P1/14A61P11/00A61P11/04A61K33/12
CPCA61K9/0095A61K33/12A61K36/00A61K36/233A61K36/26A61K36/27A61K36/282A61K36/484A61K36/532A61K36/539A61K36/575A61K36/634A61K36/8888A61K36/9064A61K2236/331A61P1/12A61P1/14A61P11/00A61P11/04A61K2300/00
Inventor 温伟波罗艳李钦
Owner 云南省中医医院
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