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Oral liquid with effects of tonifying qi, generating blood, invigorating spleen, tonifying kidneys, removing blood stasis and detoxifying and preparation method thereof
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A technology for invigorating the spleen, nourishing the kidney, invigorating qi and generating blood, which can be applied to blood diseases, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc. It can solve the problems of unsatisfactory effect, cumbersome operation and difficult industrialization. , to achieve the effect of improving quality and use effect, and improving product properties
Inactive Publication Date: 2021-02-23
HARBIN PHARM GROUP SANJING PHARMACEUTICAL CO LTD
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Abstract
Description
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[0003] This product is extracted and refined from 18 Chinese medicinal materials and then processed into oral preparations. The medicinal materials used include medicinal parts such as roots, stems and leaves, and fruits of plants. They contain many ingredients. In addition to active ingredients, they also contain protein, starch, Impurities such as resins and gums, which are unstable in oral liquid preparations, tend to aggregate and produce precipitated substances, which affect the use of the preparations
In the description of the published technical document: Shengxuekang oral liquid and its preparation method (application number 200910072889.3), after tedious refining treatment when preparing samples, the filtration time is still long, and the filter material needs to be replaced frequently, and The effect is unsatisfactory, and there are problems such as difficulty in industrialization; although the patent also uses a centrifugal treatment process after adding water to the prescription volume for sample preparation, it not only has no significant effect, but also greatly increases the working hours. Centrifugation, cumbersome operation, increases the exposure time of the liquid medicine and the probability of being contaminated by microorganisms, and the prepared samples still have the problem of long-term storage to produce sediment, which affects the use effect to a certain extent
Method used
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[0012] Preparation method: (1) add 8 times the amount of water to distill the angelica, tangerine peel, and schisandra three flavors in the prescription, collect the distillate, and redistill the distillate to obtain a redistillate for later use. (2) Take red and add 6 times the amount of 50% ethanol, reflux extraction 3 times, 2 hours each time, combine the extracts, and set aside. (3) Combine the above-mentioned distilled medicinal residues and red ginseng medicinal residues with fourteen flavors such as astragalus, dogwood, wolfberry, etc., add 14 times and 10 times the amount of water to decoct twice, the first time for 2 hours,...
[0016] Preparation method: (1) add 10 times the amount of water to distill the angelica, tangerine peel, and schisandra three flavors in the prescription, collect the distillate, and redistill the distillate to obtain the double distillate for later use. (2) Take red and add 8 times the amount of 40% ethanol, reflux extraction 3 times, 2 hours each time, combine the extracts, and set aside. (3) Combine the above-mentioned distilled medicinal residues and red ginseng medicinal residues with fourteen flavors such as astragalus, dogwood, wolfberry, etc., add 14 times and 12 times the amount of water to decoct twice, the first tim...
[0020] Preparation method: (1) add 6 times the amount of water to distill the angelica, tangerine peel, and schisandra three flavors in the prescription, collect the distillate, and redistill the distillate to obtain a double distillate for later use. (2) Take red and add 7 times the amount of 45% ethanol, reflux extraction 3 times, 2 hours each time, combine the extracts, and set aside. (3) Combine the above-mentioned distilled medicinal residues and red ginseng medicinal residues with fourteen flavors such as astragalus, dogwood, wolfberry, etc., add 10 times and 8 times the amount of water to decoct twice, the first time for 2 ho...
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Abstract
The invention provides a traditional Chinese medicine oral liquid which is proved to be safe and efficient in by clinical test proving, can be industrially produced, is mainly used for treating patients with leucopenia and erythropenia caused by radiotherapy and chemotherapy of malignant tumors, belonging to qi-blood deficiency with spleen-kidney deficiency and uncleared heat toxin, with symptomsof pale complexion, mental and physical fatigue, dizziness and tinnitus, inappetence, soreness and weakness of waist and knees, nausea and vomiting, thirst with liking for fluids and the like. The traditional Chinese medicine oral liquid is prepared from the following traditional Chinese medicinal materials: astragalus membranaceus, red ginseng, schisandra chinensis, angelica sinensis, radix paeoniae alba, poria cocos, polyporus umbellatus, caulis spatholobi, radix polygoni multiflori (processed), cornus officinalis, Chinese wolfberry fruits, glossy privet fruits, oldenlandia diffusa, madder,polygonum cuspidatum, pericarpium citri reticulatae, pinellia ternate, Chinese dates and the like. By the preparation process, the preparation process is innovatively improved, technical parameters are optimized, a refining process combining centrifugation and a filter plate is adopted under specific production steps and specific conditions, the difficult industrialization problems including filter difficulty, complicated operation, filter material and work time consumption, easy pollution and the like in the original preparation method can be solved, the product property can be improved, theproduct quality, stability and use effect can be improved, and preservative which is disadvantageous to human health and influences the product taste is removed on the premise of guaranteeing qualification of indexes and other indexes of the product.
Description
technical field [0001] The invention relates to a preparation method of an oral liquid for invigorating qi and generating blood, invigorating the spleen and kidney, removing blood stasis and detoxifying. Background technique [0002] This product is a Class 3 new drug of the original Chinese medicine approved by the state (Z20010107), and it is the exclusive Chinese medicine variety of Sanjing Pharmaceutical Co., Ltd. Its functions and indications: tonify qi and generate blood, strengthen the spleen and kidney, remove blood stasis and detoxify. It is mainly used to treat the reduction of white blood cells and red blood cells caused by radiotherapy and chemotherapy of malignant tumors, which belongs to the deficiency of both Qi and blood and the deficiency of spleen and kidney, and the heat and toxin are not cleared. Symptoms include pale complexion, fatigue, dizziness, tinnitus, loss of appetite, soreness of the waist and knees, nausea and vomiting, thirsty and fond of drink...
Claims
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Application Information
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