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Nano hydrogen free radical water for targeted removal of cytotoxic active oxygen and preparation

A free-radical and nano-technology, applied in the direction of inorganic active ingredients, medical preparations containing active ingredients, antidote, etc., can solve the problems of rupture and emission, biological safety, and the hydrogen concentration cannot reach a super-saturated state. Permeable, non-toxic effect

Pending Publication Date: 2021-07-09
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] However, using electrolysis, that is, setting positive and negative electrodes in water to decompose water into hydrogen and oxygen to generate hydrogen water (bubbles), has obvious disadvantages:
[0011] 1. Most of the ordinary air bubbles discharged into the water will not dissolve in the water, but will rise rapidly and burst into the atmosphere on the surface of the liquid; even if dissolved for a long time, the hydrogen concentration at normal temperature and pressure cannot reach supersaturation above 1.58ppm state
[0012] 2. There is biological safety: (1) If the water with many ions is electrolyzed, harmful substances such as ozone and chloroform will also be produced at the same time; (2) the metal layer of heavy metal components such as platinum on the surface of the electrolytic membrane may fall off, causing additional bodily injury
[0013] The gas permeable membrane method uses a gas permeable membrane with specific gas permeability conditions, and injects gas into the liquid solvent under a pressure exceeding a certain pressure to dissolve the gas into the liquid solvent, solving the first generation technology ( However, this method is limited by the material of the hollow fiber membrane. The current public information is that it can only produce hydrogen bubbles above 500 nanometers, and the solubility is limited, and the stability of the bubbles needs to be further improved.
At the same time, its products also have biological safety doubts about the precipitation of unknown substances in the water quality

Method used

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  • Nano hydrogen free radical water for targeted removal of cytotoxic active oxygen and preparation
  • Nano hydrogen free radical water for targeted removal of cytotoxic active oxygen and preparation
  • Nano hydrogen free radical water for targeted removal of cytotoxic active oxygen and preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] In the room 20 ° C, 4L pure water is introduced into the pure sink, start the working state, adjust the gas consolidation valve, by a blade of a microporous sheet of about 3 million average aperture 1 μm, at 4000 mm3 / 分 rate emission concentration of 99.7% of hydrogen, with (emissions of the hydrogen discharged from the blast micropore] μm 3 / 分) / (vibration frequency hz) = 33 is condition, the ionization device is continuously applied to a 2-minute frequency of 30000 Hz, an amplitude of 1 mm, and a nanochemical free radical water is obtained.

[0073] Among them, the amount of hydrogen discharged from the blast plate micropores (μm 3 / 分) is through the control valve ( figure 1 with figure 2 The instrument panel of the marker 2) is controlled. The ionization device comprises a vibrator, and the angle of the exhaust surface of the vibrator and the blast plate is 0 degrees.

[0074] The obtained nanochemical free radical water has a significant Dishir phenomenon.

[0075] ...

Embodiment 2

[0077] In the room of 20 ° C, 4L pure water is introduced into the pure sink, start the working state, adjust the air volume control valve, by having about 3 million an average aperture 1.5 μm microporous blastpened blasting, 4000 mm 3 / 分 rate emission concentration of 99.7% of hydrogen, with (emissions of the hydrogen discharged from the blast micropore] μm 3 / 分) / (vibration frequency Hz) = 100 is condition, the ionization device is continuously applied to a 2-minute frequency of 50000 Hz, an amplitude of 2 mm, and a nanochemical free radical water is obtained.

[0078] Among them, hydrogen emissions (μm 3 / 分) is controlled by controlling the valve dashboard. The ionization device comprises a vibrator, the vibrator applies vibrations within an angular range of -15 degrees to 15 degrees in the exhaust surface of the blast plate.

[0079] The obtained nanochemical free radical water has a significant Dishir phenomenon.

experiment example 1

[0091] The use of the British Malven nanoparticle tracking recorder was detected, and the product obtained by Example 1 and the proportion 1-5 was compared, and the results are shown in Table 1 below:

[0092] Table 1:

[0093] Case Died Hydrogen bubble average diameter Hydrogen bubble content half life Penetration Example 1 obvious 100nm 150 million / ml 3 months Strong Contrast 1 no Not detected no 0 weak Contrast 2 general 500nm 4 million / ml 1 month Strongest Contrast 3 obvious 200nm 80 million / ml 3 months Strong Contrast 4 More obvious 230nm 7.8 million / ml 3 months Strong Contrast 5 More obvious 210nm 7.5 million / ml 3 months Strong

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Abstract

The invention discloses nano hydrogen free radical water for targeted removal of cytotoxic active oxygen and preparation. The nano hydrogen free radical water comprises hydrogen bubbles with the particle size of 200 nm or less and hydrogen free radicals wrapped by the hydrogen bubbles; the preparation comprises the following steps: discharging hydrogen into water through a gas supply device and an aeration plate, and performing ionization treatment at the same time to obtain hydrogen free radicals wrapped by hydrogen bubbles below 200nm; and leading out liquid, filling and sealing to obtain the nano hydrogen free radical water. During ionization treatment, the ratio of the amount of hydrogen discharged by each micropore of the aeration plate to the vibration frequency during ionization is controlled to be smaller than or equal to 300. The method not only realizes production of hydrogen bubbles with the particle size of less than 200 nanometers, but also successfully realizes wrapping of hydrogen free radicals by the nano hydrogen bubbles so that a novel minimum and strongest antioxidant for anti-toxic reactive oxygen free radicals is obtained.

Description

Technical field [0001] The present invention belongs to the preparation of nanohydrate free radical water, and more particularly to the preparation method of nanochemical free radical water with targeted removal of cytotoxic active oxygen. Background technique [0002] Cancer has become the most important threat to human life. According to the statistics of the World Health Organization International Cancer Research Center, more than 1 million cases of cancer cases have been added every day. By 2020, the number of new cancer patients in the world will reach 15 million, showing an out-of control trend. [0003] China National Cancer Center released the latest national cancer statistics in January 2019, 2015 China's new malignant tumor case number is approximately 3929,000 cases, and the annual growth rate of about 4% has grown in the past decade, of which lung cancer ( 17.8%), gastric cancer (10.4%) and liver cancer (8.8%) have the greatest killing. Cancer not only torture the pat...

Claims

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Application Information

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IPC IPC(8): C02F1/68A61K33/00A61P39/02A61P39/06
CPCC02F1/68A61K33/00A61P39/02A61P39/06
Inventor 福田浩平解冰
Owner 解冰
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