Yin-nourishing traditional Chinese medicine composition containing liquorice and dandelion and application of yin-nourishing traditional Chinese medicine composition

Abstract

The invention provides a composition (named as liquorice yin-nourishing decoction) containing medicinal and edible traditional Chinese medicine components such as liquorice and application of the composition in the aspects of rheumatoid arthritis and ovarian cancer. The traditional Chinese medicine composition of the liquorice yin-nourishing decoction is prepared from the following components in parts by weight: 2-6 parts of liquorice, 1-5 parts of ginseng, 1-3 parts of dried ginger, 1-3 parts of dandelion, 2-6 parts of momordica grosvenori, 1-5 parts of radix polygonati officinalis and 2-6 parts of Chinese dates. According to the traditional Chinese medicine composition, the liquorice is used as a monarch drug, the ginseng and the radix polygonati officinalis are used as ministerial drugs, the dandelion, the rhizoma zingiberis and the momordica grosvenori are used as adjuvant drugs, and the Chinese dates are used as a conductant drug, and the traditional Chinese medicine composition can tonify qi and invigorate the middle warmer, clear away heat and toxic materials, nourish blood and tranquilize the mind, moisten the lung to arrest cough, engender fluid and quench thirst, nourish yin and strengthen yang, and regulate heart meridian, lung meridian, spleen meridian and large intestine meridian. In-vitro research proves that the medicinal serum of the formula inhibits proliferation activity of rheumatoid arthritis synovial fibroblasts and ovarian cancer cells and promotes apoptosis of the rheumatoid arthritis synovial fibroblasts and the ovarian cancer cells. The potential development value is realized in the treatment of rheumatoid arthritis and ovarian cancer.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a traditional Chinese medicine composition for nourishing yin containing licorice and dandelion and an application thereof. Background technique [0002] Rheumatoid arthritis (rheumatoid arthritis, RA) is one of the most common rheumatic diseases in rheumatic diseases, and the prevalence is as high as 0.5-1.0% of the population (MCINNES I B, SCHETT G. Pathogenetic insights from the treatment of rheumatoid arthritis[J]. Lancet. 2017, 389(10086): 2328-2337.). Rheumatoid arthritis is a serious hazard, and its prominent pathological feature is synovial hyperplasia and erosion of articular cartilage and bone, eventually leading to joint destruction and deformity. The clinical manifestations are joint pain, deformation and loss of function, and even involve multiple systems and organs of the human body, concurrent with interstitial lung di...

AI Technical Summary

Problems solved by technology

The lack of strict randomized clinical trials and convincing basic research hinders the application and promotion of traditional Chinese medicine

Images