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Pharmaceutical composition comprising NMN and application thereof

A technology of composition and medicine, which is applied in the field of medicine, can solve the problems of large dosage and poor curative effect of NMN, and achieve the effect of improving sleep function, sleep improvement, and simple and clear drug composition

Active Publication Date: 2021-07-30
SUZHOU RENBEN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In order to overcome the problems of large dosage and poor curative effect of NMN, the present invention provides a pharmaceutical composition including NMN and its application, and also provides a kind of tryptophan or tryptophan and vitamin B 3 new uses of the composition

Method used

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  • Pharmaceutical composition comprising NMN and application thereof
  • Pharmaceutical composition comprising NMN and application thereof
  • Pharmaceutical composition comprising NMN and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0057] The composition of the synergist in this embodiment is: 4.7 g of L-tryptophan.

[0058] The composition of the pharmaceutical composition in this embodiment is: 4.7g of L-tryptophan, 30g of NMN.

[0059] The preparation method of the pharmaceutical composition is as follows: respectively take selected weights of L-tryptophan and NMN, mix them uniformly, and obtain the product.

[0060]The pharmaceutical composition of this embodiment is prepared into tablets by adding conventional excipients and following conventional techniques.

Embodiment 2

[0062] The composition of the synergist in this embodiment is: 86g of L-tryptophan.

[0063] The raw material composition of the pharmaceutical composition of this embodiment is: L-tryptophan 86g, NMN 3g.

[0064] The preparation method of the pharmaceutical composition is as follows: respectively take selected weights of L-tryptophan and NMN, mix them uniformly, and obtain the product.

[0065] The pharmaceutical composition of this embodiment is prepared into capsules by adding conventional excipients and following conventional techniques.

Embodiment 3

[0067] The composition of the synergist in this embodiment is: 50 g of L-tryptophan.

[0068] The pharmaceutical composition of this embodiment consists of: L-tryptophan 50g, NMN 100g.

[0069] The preparation method of the pharmaceutical composition is as follows: respectively take selected weights of L-tryptophan and NMN, mix them uniformly, and obtain the product.

[0070] The pharmaceutical composition of this embodiment is added into distilled water and dissolved to make a solution.

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Abstract

The invention provides a pharmaceutical composition containing NMN and application of the pharmaceutical composition, and further provides application of tryptophan or a composition containing tryptophan and vitamin B3 in preparation of an NMN synergist. It is found that no obvious sleep improving effect exists when the NMN, the vitamin B3 and the tryptophan are singly used, but the tryptophan or a composition of the tryptophan and the vitamin B3 can improve the sleep improving effect of the NMN, so that the tryptophan and the vitamin B3 can form a compound with the obvious sleep improving effect together. Herein, the pharmaceutical composition comprises tryptophan and NMN, or the pharmaceutical composition comprises tryptophan, vitamin B3 and NMN, or the pharmaceutical composition comprises tryptophan, vitamin B3, NMN, a grape seed extract, an apocynum venetum extract and dendrobium officinale. The composition not only has the effect of remarkably improving sleep, but also has the effect of improving sleep remarkably superior to that of a single component.

Description

technical field [0001] The invention belongs to the field of medicines and relates to a pharmaceutical composition including NMN and its application. Background technique [0002] Modern epidemiological studies have shown that 15-35% of adults have sleep quality problems. Factors such as work and life pressure, addiction to mobile phones and games, mental stress and diseases are all seriously affecting the sleep quality of young and old people. The problem of sleep quality is not only related to the occurrence and development of various mental disorders, but also a high-risk factor for various physical diseases, accidents and death. Sleep quality also affects aging and life expectancy. The sleep cycle consists of non-REM and REM cycles. Non-rapid eye movement sleep is divided into 4 stages of light sleep, light sleep, middle sleep and deep sleep, and then enters rapid eye movement sleep, which is the end of a sleep cycle, and then continues to start the next sleep cycle. S...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/706A61K31/405A61K31/455A61K36/87A61K36/24A61K36/8984A61P25/20
CPCA61K31/706A61K31/405A61K31/455A61K36/87A61K36/24A61K36/8984A61P25/20A61K2300/00
Inventor 秦正红朱路佳
Owner SUZHOU RENBEN PHARMA
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