Bactericidal composition and application thereof

A composition and protozoan technology, applied in the direction of drug combination, antifungal agent, non-active ingredient medical preparations, etc., can solve problems such as ineffective prevention and treatment of aquaculture diseases, and achieve good preventive effect and good therapeutic effect Effect

Pending Publication Date: 2021-10-08
湖北至正天辰生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the above-mentioned technical deficiencies, provide a bactericidal composition and its application, and solve the technical problem that the drugs with low toxicity in the prior art cannot efficiently prevent and treat aquaculture diseases

Method used

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  • Bactericidal composition and application thereof
  • Bactericidal composition and application thereof
  • Bactericidal composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] In order to determine the synergistic effect of the combination of diallyl disulfide and dithiocyanomethane as two active ingredients, the applicant first used these two ingredients to conduct an indoor biotest. The test method and results are as follows:

[0029] 1. The saprolegniates used in the embodiments of the present invention are conventional saprolegniates, which are cultivated according to conventional methods in the art.

[0030] 2. Test method:

[0031] 2.1 Test concentration design: first pre-test the bactericidal composition with different ratios, and dilute it into different concentration gradients according to the relationship of 10 times. According to the results of the pre-test, the inhibitory rate of each agent on the growth of pathogenic hyphae reaches 10% to 90%. 5 concentration gradients were designed within the range of % to carry out precise experiments.

[0032] 2.2 Antibacterial test method: The mycelial growth rate method was used to determin...

Embodiment 2

[0050] This embodiment proposes a bactericidal composition, calculated in parts by weight, comprising: 30 parts of diallyl disulfide, 2 parts of dithiocyanomethane, 16 parts of dimethylformamide, 42 parts of organic solvent methanol, Emulsifier OP-1010 parts.

Embodiment 3

[0052] This embodiment proposes a bactericidal composition, calculated in parts by weight, comprising: 20 parts of diallyl disulfide, 2 parts of dithiocyanomethane, 16 parts of dimethylformamide, 52 parts of organic solvent methanol, Emulsifier OP-1010 parts.

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PUM

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Abstract

The invention discloses a bactericidal composition. The bactericidal composition is prepared from diallyl disulfide and methane dithiocyanate, the mass ratio of the diallyl disulfide to the methane dithiocyanate is (1-20): (1-8), and the bactericidal composition belongs to the technical field of prevention and treatment of diseases of aquaculture animals. The bactericidal composition provided by the invention further comprises application of the bactericidal composition in preparation of drugs for preventing or treating aquaculture diseases. The bactericidal composition has a good prevention effect on saprolegniasis of grass carps or crucian carps.

Description

technical field [0001] The invention relates to the technical field of aquaculture animal disease prevention and control, in particular to a bactericidal composition and application thereof. Background technique [0002] Saprolegniasis: also known as skin mildew and white hair disease, is a common secondary disease caused by a variety of aquatic fungi. There is no strict selection for the species of aquatic animals. It is a worldwide distribution and is harmful to farmed fish. more dangerous diseases. [0003] Trichotilloides: a genus belonging to the phylum Protozoa, the subphylum Cilia, the class Oligomembrane, the order Ciliata, and the family Citriforme. It mainly parasitizes freshwater fish in my country. The disease caused by the parasitism of trichomonas has always been the most common disease in aquaculture. The disease is mainly prevalent from April to July every year, and it is widely popular, spreads quickly, and has serious damage. [0004] For a long time, th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/275A61K47/18A61P31/10A61P33/02A61K31/255
CPCA61K31/255A61K31/275A61K47/18A61P31/10A61P33/02A61K2300/00
Inventor 荣克明徐盛昌
Owner 湖北至正天辰生物科技有限公司
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