Preparation device of nano medicinal preparation

Abstract

The invention discloses a preparation device of a nano medicinal preparation. The preparation device comprises a cylinder with a bottom frame, an annular plate is rotatably connected to the top end of the cylinder, two emulsifying mechanisms are arranged in the annular plate, each emulsifying mechanism comprises a first motor, a stirring shaft and an electric push rod, limiting grooves are formed in the two sides of each stirring shaft, and limiting pieces are slidably connected into the limiting grooves. A plurality of stirring blades are further fixed to the outer side of the stirring shaft, a telescopic shaft of the electric push rod extends into the barrel, a lantern ring is fixed to the bottom end of the telescopic shaft, and the lantern ring is rotationally connected to the outer side, close to the top, of the stirring shaft. An annular plate is rotationally connected to the top end of the cylinder, when the annular plate rotates at the top end of the cylinder, the transverse position of the emulsifying mechanism can be driven to be adjusted, the mixing uniformity of materials in the cylinder is better when the annular plate is matched with the vertical stirring effect, the stirring shaft can be driven by the electric push rod to be adjusted in the vertical space, and the uniform distribution of the materials is improved by mixing the materials of different parts for use.

Description

technical field [0001] The invention belongs to the technical field of preparation devices for nano-medicine particles, and in particular relates to a preparation device for nano-medicine preparations. Background technique [0002] Nanoparticles in pharmacy, or nanocarriers and nanomedicines, are defined in size between 1-1000nm. Nanocarriers refer to various nanoparticles in which drugs are dissolved or dispersed. Nano-medicine refers to the direct processing of raw materials into nanoparticles. The research on nanoparticles in the field of pharmacy was earlier than the emergence of the concept of "nanotechnology". In the 1970s, various nanocarriers such as nanoliposomes, polymer nanocapsules and nanospheres had been studied. The routes of administration involved include injection, oral administration, and ophthalmic administration. In the field of drug delivery systems, the size of nanoparticles is generally defined in the range of 1-1000 nm, which includes submicron pa...

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Problems solved by technology

[0004] However, nano-pharmaceutical preparations are thermodynamically and kinetically unstable systems, and their physical stability is poor, and they are prone to unstable phenomena such as growth, agglomeration, and sedimentation, which will seriously affect the quality of nano-pharmaceutical preparations.

[0005] The mixing uniformity of raw materials in the preparation process of existing nanoparticle medicine is poor, so the particle size uniformity of the prepared nanomedicine is poor, which affects the quality of nanomedicine

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