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Veterinary paris polyphylla injection for relieving pain and preparation process thereof

A preparation process and injection technology, applied in the direction of non-central analgesics, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., to relieve and relieve pain, broad market prospects, relieve and relieve pain Effect

Pending Publication Date: 2021-12-14
杭州艾贝德生命科技研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Chonglou has the effects of clearing heat, detoxifying, reducing swelling and relieving pain. It is a commonly used drug for treating furuncle and snake bites. It can treat sore throat and joint swelling and pain. However, at present, Chonglou is rarely prepared as an injection for animal pain relief.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A preparation process of veterinary analgesic Chonglou injection, comprising the following steps:

[0024] (a) Wash, dry, and pulverize the chrysanthemum for later use; remove impurities from the above-mentioned medicines, weigh them, add 25,000-30,000 ml of water, soak for 40-60 minutes, and then decoct. Chonglou (broken residue) was decocted twice, each time for about two hours, and the obtained medicinal solution was filtered with four layers of gauze. The filtrate was concentrated to about 3000 ml.

[0025] (b) Add ethanol to the concentrated solution to adjust the alcohol content to over 60%, stir well, let stand for 24 hours, filter with two layers of filter paper, recover ethanol, and then concentrate to about 3000 ml.

[0026] (c) Add ethanol to the concentrated solution to adjust the alcohol content to more than 75%, let it stand for about 40 hours, filter with three layers of filter paper, recover ethanol, and concentrate to about 3000 ml.

[0027] (d) Add w...

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PUM

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Abstract

The invention discloses a veterinary paris polyphylla injection for relieving pain. 10000 ml of the paris polyphylla injection comprises the following components in parts by weight: about 3 kg of paris polyphylla, 80-100 ml of tween-80, 80-100 ml of benzyl alcohol and the balance of water for injection. The preparation process of the paris polyphylla injection comprises the following steps: crushing the paris polyphylla, adding a certain amount of water for injection, decocting, filtering, concentrating, adjusting the alcohol content with ethanol for multiple times, concentrating, carrying out suction filtration to recover ethanol, diluting and refrigerating with water for injection, boiling and adsorbing with activated carbon, filtering and recovering activated carbon, adjusting the pH value with sodium hydroxide, adding Tween-80 and benzyl alcohol, diluting to a constant volume again, and finally sterilizing and canning. The veterinary paris polyphylla injection not only can effectively relieve and relieve pains of animals, but also can reduce various complications, and has a good curative effect and a wide market prospect.

Description

technical field [0001] The invention relates to a Chinese herbal medicine preparation, in particular to a preparation process of veterinary analgesic Chonglou injection. Background technique [0002] Chonglou is the dry rhizome of Yunnan Chonglou or Aescin, a plant of Liliaceae. Chonglou is a unique and precious medicinal material in China. It is a perennial herb. Cultivated artificially. The leaves are 6-10 pieces in whorls, the petiole length is 5-20mm, the leaves are thick papery, lanceolate, ovate-oblong to obovate, green, 3.5-6cm long; the perianth pieces are linear and slightly draped Needle-shaped, yellow, about 1 / 2 of sepals to almost equal in length, 2-6mm wide above the middle; stamens 8-10mm, anthers 1-1.5cm long, filaments shorter than anthers, connective protruding part 1-2mm. Chonglou contains a variety of steroidal saponins, which are the diosgenin and pinanogenin 23 tetraglycosides, and also contains beta ecdysone, carotin, etc., which are the main raw mater...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K36/896A61K47/10A61K47/26A61P25/00A61P29/00A61P31/04
CPCA61K36/896A61K9/08A61K9/0019A61K47/26A61K47/10A61P25/00A61P29/00A61P31/04A61K2236/333A61K2236/53
Inventor 王宝贵刘文莉
Owner 杭州艾贝德生命科技研究院有限公司
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