Unlock instant, AI-driven research and patent intelligence for your innovation.

Application of dendranthema morifolium volatile oil and composition thereof in preparation of product for treating glucose and lipid metabolism comprehensive disorder

A technology of golden silk chrysanthemum and glucose and lipid metabolism, applied in the fields of application, metabolic diseases, drug combination, etc., can solve problems that do not involve hypoglycemic and hypolipidemic activity, component efficacy testing, etc. Achieving low cost, good hypoglycemic and hypolipidemic activity, and favorable preservation effects

Active Publication Date: 2021-12-14
TIANJIN UNIV OF SCI & TECH
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This patent publication does not involve hypoglycemic and hypolipidemic activities and the application of products in the treatment of comprehensive disorders of glucose and lipid metabolism
3. Application of geranyl citrus chalcone and its composition in the preparation of products for treating fatty liver (CN111388457A), which discloses 3'-geranyl citrus chalcone and its combination with the extract of Rustica chrysanthemum The application of the preparation for the treatment of fatty liver. The main active ingredient of this patent is 3'-geranyl citrus chalcone. The extract of Rustica chrysanthemum is only a synergistic effect and does not involve the volatile oil of Rustica chrysanthemum. Does not involve dual effects of lowering blood sugar and blood fat
This paper analyzed the chrysanthemum collected from the biological garden of Jinggangshan University, extracted its volatile oil by ordinary steam distillation, and identified the structure of volatile oil in four parts of chrysanthemum leaves, stems, roots and flowers by gas chromatography-mass spectrometry, but did not Efficacy testing of ingredients

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of dendranthema morifolium volatile oil and composition thereof in preparation of product for treating glucose and lipid metabolism comprehensive disorder
  • Application of dendranthema morifolium volatile oil and composition thereof in preparation of product for treating glucose and lipid metabolism comprehensive disorder
  • Application of dendranthema morifolium volatile oil and composition thereof in preparation of product for treating glucose and lipid metabolism comprehensive disorder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Optimization of a method for extracting volatile oil from Chrysanthemum chrysanthemum:

[0067] Extraction rate of volatile oil from Chrysanthemum chrysanthemum under different conditions in table 1

[0068]

[0069]

[0070] It can be known from Table 1 that the extraction rate is higher when the extraction solvent in the volatile oil extractor and post-treatment is ether, and the extraction rate is the highest when the heating temperature of the external bath is 150°C and the extraction time is 9 hours.

Embodiment 2

[0072] A process for extracting the volatile oil of Chrysanthemum chrysanthemum:

[0073] S1 adopts the steam distillation extraction method, weighs a certain amount of Chrysanthemum chrysanthemum flowers and leaves, carries out superfine grinding, transfers them to a round bottom flask, adds deionized water with a material-to-liquid ratio of 1:10, and then adds zeolite to connect the volatile oil Extractor, and add ether in the volatile oil extractor, connect the decompression device on the upper part of the reflux condenser, and connect the reflux condenser to the low-temperature constant temperature circulation condenser for condensation.

[0074] S2 Under reduced pressure, heat the water to boiling, reflux and extract for 3-9 hours, collect the ether layer, extract the water layer twice with ether, combine the ether layers, dry over anhydrous sodium sulfate, and distill off the ether to obtain light yellow gold wire The volatile oil of Huang chrysanthemum flowers and leave...

Embodiment 3

[0078] Liquid-mass spectrometry analysis of the extracted volatile oil of Chrysanthemum chrysanthemum:

[0079] According to the "National Pharmacopoeia of the People's Republic of China 2010 Edition" volatile oil assay method, the chemical composition analysis adopts gas chromatography-mass spectrometry detection (GC-MS) analysis, and the analysis conditions are as follows:

[0080] Detection instrument: American Agilent 5975C+7890A gas chromatography-mass spectrometer.

[0081] Chromatographic conditions: HP-5MS elastic quartz capillary column (0.25μm×30m×0.25mm), the initial temperature of the programmed temperature rise is 40°C, keep for 3min, rise to 160°C at 4°C / min, keep for 3min, and keep at 6°C / min Rise to 280°C, hold for 10min, use high-purity helium (99.99%) as carrier gas, volume flow rate is 1.0mL / min, split ratio is 50:1, and injection volume is 1.0μL.

[0082] Mass spectrometry conditions: electron bombardment (EI) ion source, electron energy 70eV, solvent dela...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses application of dendranthema morifolium volatile oil and a composition thereof in preparation of a product for treating glucose and lipid metabolism comprehensive disorder. It is found for the first time that the volatile oil in flowers and / or leaves of the dendranthema morifolium has remarkable blood sugar reducing and / or blood fat reducing activity, and the application field of the agricultural product- dendranthema morifolium and downstream high-added-value products is expanded; and the dendranthema morifolium volatile oil and the volatile oil and extract composition can be applied to the preparation of the product for treating glucose and lipid metabolism comprehensive disorder and related diseases.

Description

technical field The invention belongs to the technical field of medicine and functional food, and relates to the new application of natural plant molecules and compositions thereof, in particular to the application of a quintessence chrysanthemum volatile oil and its composition in preparing products for treating comprehensive disorders of glucose and lipid metabolism. Background technique Golden silk chrysanthemum was named after Huang Tingjian, a poet in the Southern Song Dynasty, who sent the chrysanthemum to the imperial court and was bestowed the name golden silk chrysanthemum by the emperor. Golden Silk Chrysanthemum not only has good ornamental value, but also has a fragrant smell, sweet and bitter taste, and slightly cold nature. Modern medical research shows that Golden Silk Chrysanthemum contains extremely high flavonoids and is rich in various amino acids, vitamins and trace elements. , has the magical effect of anti-fatigue and anti-aging, and is favored by cons...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/287A61P3/10A61P3/06A23L33/105A61K133/00A61K127/00
CPCA61K36/287A61P3/10A61P3/06A23L33/105A23V2002/00A61K2236/331A23V2200/328A23V2200/3262A23V2250/21
Inventor 孙华张欣颖李想王雪玉汪海波
Owner TIANJIN UNIV OF SCI & TECH