Traditional Chinese medicine composition and medicine for preventing postoperative recurrence of brain glioma as well as preparation method and application of medicine

Abstract

The invention relates to a traditional Chinese medicine composition and medicine for preventing postoperative recurrence of brain glioma as well as a preparation method and application of the medicine, and can effectively solve the problem of medication for preventing postoperative relapse of glioma. According to the method, the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 1-8 parts of codonopsis pilosula, 1-5 parts of scutellaria baicalensis, 1-5 parts of crude dragon bone, 1-5 parts of raw oysters, 1-15 parts of cassia twigs, 1-10 parts of poria cocos, 1-5 parts of rhizoma pinelliae preparata, 1-8 parts of radix bupleuri, 1-15 parts of radix et rhizoma rhei, 1-5 parts of fried semen pharbitidis, 1-7 parts of cortex moutan, 1-15 parts of gypsum, 1-5 parts of gypsum rubrum, 1-7 parts of rhizoma zingiberis, 1-7 parts of bulbus fritillariae thunbergii, 1-10 parts of radix scrophulariae, 1-8 parts of radix glycyrrhizae and 1-5 parts of fructus jujubae. The traditional Chinese medicine composition disclosed by the invention is scientific and reasonable in components, simple in preparation method, easy to operate, low in cost, convenient to take, good in effect and easy to produce and prepare, is an innovation of medicines for preventing postoperative relapse of brain glioma, and has good economic and social benefits.

Description

[0001] This application is a divisional application with an application date of March 16, 2017, an application number of 201710156755.4, and an invention title of "A Traditional Chinese Medicine Composition for Preventing Postoperative Recurrence of Brain Glioma". technical field [0002] The invention relates to medicine, in particular to a traditional Chinese medicine composition and medicine for preventing postoperative recurrence of brain glioma, a preparation method and application thereof. Background technique [0003] Glioma is a primary tumor caused by the canceration of glial cells in the brain and spinal cord. It is one of the most common tumors in the central nervous system, accounting for about 30-50% of brain tumors, and has a high incidence and recurrence rate. , high mortality, and low cure rate, the etiology of the disease is still unclear so far. The annual incidence of glioma in China is 3-6 people per 100,000 people. In recent years, the incidence of gliom...

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Problems solved by technology

[0004] Surgical resection is still the main treatment for glioma, supplemented by radiotherapy and chemotherapy. However, because glioma presents infiltrating unlimited hyperplasia, lack of apoptosis, and no obvious boundary with normal brain tissue, it invades multiple The lobes of the brain, even invading the important functional areas of the deep brain, are difficult to completely remove by surgery; and because glioma cells are not sensitive to radiation, chemotherapy drugs are difficult to penetrate the blood-brain barrier and have drug resistance, leading to the clinical manifestations of glioma. The effect of radiotherapy and chemotherapy is not satisfactory, so it has a high recurrence rate, the average survival period is 6 months, and the survival period of comprehensive treatment is less than 2 years

However, at present, surgical resection, radiotherapy, and chemotherapy are all severe methods of attacking evil, which will make the damaged righteousness of the patient more exhausted, which is not conducive to the recovery of the disease and prolongs the survival of the patient.

[0005] Although there are a variety of drugs for the treatment and prevention of postoperative recurrence of glioma, their use is not satisfactory due to various reasons, especially the problems in the composition of the drugs. Post-Relapse Medication Imperative

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