Method for tracing and analyzing drug content in health care product by auxiliary agent

A technology of trace analysis and health care products, which is applied in the direction of analysis of materials, material stimulation analysis, preparation of test samples, etc.

Pending Publication Date: 2022-03-11
GUILIN MEDICAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] Based on this, the purpose of the present invention is to provide a method for tracer analysis of drug content in health care products with adjuvants. The method of the present invention overcomes the difficult problem of separating the analyte from the complex system of health care products. The steps are simple, easy to operate, and sensitive. High, rapid detection, suitable for rapid analysis of drug content in health products

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  • Method for tracing and analyzing drug content in health care product by auxiliary agent
  • Method for tracing and analyzing drug content in health care product by auxiliary agent
  • Method for tracing and analyzing drug content in health care product by auxiliary agent

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Embodiment Construction

[0032] In order to further illustrate the present invention, this embodiment takes the health care product containing illegally added phenothiazine psychotropic drugs as an example, and describes in detail the method for analyzing the drug content in the health care product by adjuvant tracer. However, those skilled in the art should understand that this specific example is a specific elaboration of the idea of ​​the present invention, and does not constitute a limitation to the alternative embodiments of the present invention. Those skilled in the art can also use this method to measure the drug content according to actual health products. The method of the invention is carried out.

[0033] Specifically, the present embodiment takes the health care product containing the phenothiazine psychotropic drug chlorpromazine hydrochloride as an example, that is, the health care product contains a certain amount of chlorpromazine hydrochloride, and the commonly used drug solvent ethan...

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Abstract

According to the method for tracing and analyzing the drug content in the health care product through the auxiliary agent, the drug in the health care product can be subjected to photolysis reaction and generate free radicals, the free radicals generated in the photolysis process of the drug are captured through the drug auxiliary agent to generate a volatile first component, then the first component with the low boiling point is separated out through the gas-liquid separation technology, and the content of the drug in the health care product is analyzed through the gas-liquid separation technology. And carrying out derivatization reaction on the first component and a derivatization reagent, and determining the content of the medicines in the health care product by adopting surface enhanced Raman spectroscopy. Compared with the prior art, the method for tracing and analyzing the drug content in the health-care product by the aid of the auxiliary agent has the advantages that the time required by sample pretreatment is shortened, the detection and analysis process of the drug content in the health-care product is greatly simplified, the steps are simple, and the sensitivity is high.

Description

technical field [0001] The invention relates to the field of impurity analysis and detection of health-care products, in particular to a method for tracking and analyzing drug content in health-care products by adjuvant. Background technique [0002] Health food has a regulating effect and is a special food not for the purpose of treating diseases. Drugs cannot be illegally added to health products. However, in recent years, with the increasing demand for health care products in the market, the phenomenon of illegally adding drugs to health food products has been repeatedly prohibited. For example, due to the sedative effect of phenothiazine psychotropic drugs, some unscrupulous businessmen illegally add phenothiazine psychotropic drugs to health care products in order to improve the efficacy of health care products, such as improving sleep quality. Therefore, the development of simple, fast and accurate detection methods for illegally added drug content in health products ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/65G01N1/38G01N1/44
CPCG01N21/658G01N1/38G01N1/44
Inventor 陈正毅谢俊袁锟婷林砚潘宇
Owner GUILIN MEDICAL UNIVERSITY
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