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Space mutagenesis high production and highly performance bacterial and use thereof

A kind of use and strain technology, applied in the field of high-efficiency strains for space mutagenesis, can solve the problems of low mannan peptide content, low yield, and small application range

Active Publication Date: 2006-02-01
陕西神舟太空食品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the yield is low, the scope of application is small, and the content of mannan peptide is small

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0089] 1 gram of mannan peptide produced by space-mutated strains; appropriate amount of sweetener and essence; made into 1000ml.

[0090] Dissolve 1g of mannan peptide produced by space-induced mutagenic strains and 0.15g of sodium saccharin in a small amount of purified water, add 0.1ml of essence, add purified water to 1000ml, stir well, filter, after passing the test, potting, and steaming bacteria at 121°C for 30 minutes.

Embodiment 2

[0092] Mannan peptide raw material liquid 1000ml produced by space mutagenesis strains, activated carbon 0.25g, protein sugar 0.8g, made into 1000ml. Take 1000ml of the mannan peptide raw material solution produced by space-induced mutagenic strains, add 0.25g of activated carbon, stir well, filter, add 0.8g of protein sugar, stir well, after passing the test, potting, steam sterilization at 121°C, 30 minute.

Embodiment 3

[0094] Mannan Peptides 1g

[0095] Propylene glycol 100g

[0096] Chlorobutanol 5g

[0097] Purified water made 1000ml

[0098] Take 1g of mannan peptide, 5g of chlorobutanol, add 800ml of purified water to dissolve, then add 100g of propylene glycol to mix evenly, filter, add water from the filter to the full amount, stir well, circulate steam for 30 minutes, pack Put it into a spray bottle that has been cleaned and sterilized beforehand.

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PUM

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Abstract

The invention relates to a space mutagenized strain and its uses characterized in that the alpha-streptococcus hemolyticus strain is carried to the outer space by the shuttle spacecraft, and mutagenized under the special conditions of outer space to mutate in heredity property, and after returning to the earth, the strain with positive mutation and stable heredity property is selective as the production strain. The strain is preserved in China General Microbiological Culture Collection Center with serial number CGMCCNo.1082. Said alpha-streptococcus hemolyticus strain is alpha-streptococcus hemolyticus No.33. The stain has advantages of high yield, wide use, and high availability.

Description

technical field [0001] The invention relates to a high-yield and high-efficiency bacterial strain induced by space mutation, in particular to a high-efficiency bacterial strain induced by space mutation and its application. Background technique [0002] The drug mannan peptide produced by the common α-hemolytic streptococcus No. 33 was listed in China as early as 1986. It is only used as an immune enhancer. The pharmacological effect is to activate lymphocytes, promote the differentiation and proliferation of thymus lymphocytes, and promote Anti-tumor immune function, activate macrophages, increase leukocyte production, promote complement production, promote interleukin-1 production, and improve bone marrow hematopoietic function. But the yield is low, the range of application is small, and the content of mannan peptide is small. Contents of the invention [0003] The object of the present invention is to provide a kind of...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/20C12N13/00C12P1/04C12P21/02A61P37/04
Inventor 赵恒
Owner 陕西神舟太空食品有限公司