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Achillea total flavone capsule

A technology of total flavonoids and capsules, which is applied in the field of Yizhi Artemisia total flavonoids capsules, which can solve problems such as unfavorable recovery from liver diseases and liver damage

Inactive Publication Date: 2002-11-20
斯拉甫·艾白 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, many drugs must be oxidized, decomposed, and excreted in the liver, and some can directly cause liver damage, which is not conducive to the recovery of liver disease

Method used

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  • Achillea total flavone capsule
  • Achillea total flavone capsule
  • Achillea total flavone capsule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] a. Firstly crush 10kg of Artemisia argyi whole herb into powder, reflux extract with 5 times of 95% ethanol three times, the reflux temperature is 70°C, degrease the extracted alcohol extract with 400ml petroleum ether, filter, and remove the petroleum ether layer , retaining its residue;

[0069] b. Extract the retained residue three times with 400ml ethyl acetate, the extraction temperature is normal temperature, filter, filter off the ethyl acetate insoluble matter, decolorize the remaining ethyl acetate layer with 0.5% activated carbon, and concentrate under reduced pressure to a relatively An extract with a density of 1.10, the effective parts of which are total flavonoids and ketoacids, the content of which is 50%;

[0070] c. Then vacuum-dry the concentrated extract at 45°C to obtain a dry paste, add starch to the dry paste to prepare granules, dry at a low temperature of 45°C, arrange, and pack into capsules to obtain the finished product.

[0071] Use Yizhihao...

Embodiment 2

[0073] a. First, crush 10kg of Artemisia argyi whole herb into powder, reflux and extract with 6 times 75% ethanol three times, the reflux temperature is 75°C, degrease the extracted alcohol extract with 500ml petroleum ether, filter, and remove the petroleum ether layer , retaining its residue;

[0074] b. Extract the retained residue three times with 500ml ethyl acetate, the extraction temperature is normal temperature, filter, filter off the ethyl acetate insoluble matter, decolorize the remaining ethyl acetate layer with 0.8% activated carbon, and concentrate under reduced pressure to a relative An extract with a density of 1.25, the effective parts of which are total flavonoids and ketoacids, the content of which is 70%;

[0075] c. Then vacuum-dry the concentrated extract at 60°C to obtain a dry paste, add starch to the dry paste to prepare granules, dry at a low temperature of 50°C, arrange, and pack into capsules to obtain the finished product.

[0076] Use Yizhi Arte...

Embodiment 3

[0078] a. Firstly crush 10kg of Artemisia argyi whole herb into powder, reflux extract with 6 times of 85% ethanol three times, the reflux temperature is 80°C, degrease the extracted alcohol extract with 600ml petroleum ether, filter and remove the petroleum ether layer , retaining its residue;

[0079] b. Extract the retained residue three times with 600ml ethyl acetate, the extraction temperature is normal temperature, filter, filter off the ethyl acetate insoluble matter, decolorize the remaining ethyl acetate layer with 1% activated carbon, and concentrate under reduced pressure to a relatively An extract with a density of 1.30, the effective parts of which are total flavonoids and ketoacids, the content of which is 80%;

[0080] c. Then vacuum-dry the concentrated extract at 50°C to obtain a dry paste, add starch to the dry paste to prepare granules, dry at a low temperature of 60°C, arrange, and pack into capsules to obtain the finished product.

[0081] Use Yizhi Artem...

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PUM

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Abstract

The preparation method of achillea total flavone capsule for curing virus hepatitis and various hepatic injuries with total effective rate of 91.0% includes the following steps: using achillea as rawmaterial, pulverizing, using ethyl alcohol to make extraction, using petroleum ether to degrease, using ethyl acetate to make extraction, concentrating to obtain extract, in which effective region total flavone and keto-acid content is 50-80%, then vacuum drying extract to obtain dried extract, adding starch and making them into granules, low-temp. drying, finishing and capsulizing so as to obtain the invented finished product. Said invented product has no toxic side effect.

Description

technical field [0001] The invention relates to a medicine for treating viral hepatitis and various liver damage diseases mainly by preparing Yizhi Artemisia flavonoids capsules from Chinese herbal medicines. Background technique [0002] Viral hepatitis and liver injury are diseases that damage human health. Among them, viral hepatitis is a global infectious disease that seriously endangers human health. The prognosis of patients is poor. Most patients become chronic and may develop into liver cirrhosis. Liver damage caused by viral hepatitis is mainly mediated by the body's immune response. When the virus activates the body's immune system, it produces sensitized lymphocytes and specific antibodies, especially virus-specific cytotoxic T cells. They can not only react with the virus in the body to kill, but also cause liver damage due to the viral antigen on the surface of the virus-infected liver cells, leading to degeneration, swelling and necrosis o...

Claims

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Application Information

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IPC IPC(8): A61K31/352A61P1/16A61P31/12
Inventor 斯拉甫·艾白哈木拉提·吾甫尔阿吉艾克拜尔阿不都热衣木·玉苏甫古力娜·达吾提
Owner 斯拉甫·艾白
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