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Capsule possessing antiinflammation, releaving pain and anticancer function and its preparation method

A technology for capsules and preparations, applied in the field of traditional Chinese medicine, can solve problems such as inconvenience for patients to take, loss of dose, unsanitary, etc., and achieve the effects of improving blood rheology, preventing loss and preventing volatilization.

Inactive Publication Date: 2004-03-03
四川省天基生物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, since this product is a prescription for dispelling stagnation, reducing swelling, removing blood stasis, and relieving pain, it is necessary to choose a solid preparation that is easy to store, carry, and swallow. It needs to be broken and taken, which is very inconvenient and unhygienic for patients to take, and the dosage will be greatly lost; since most of the medicinal materials contain water-insoluble ingredients, the preparation is complicated. Water pan pills are made and dried (at a temperature of 50°C to 70°C), the loss of active ingredients is large, and the identification method is single, only qualitative identification of the pills, no index components, and difficult quality control

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0024] Experimental Example 1 The preparation of capsules of the present invention

[0025] a, take the following Chinese medicinal materials as raw materials:

[0026] 1.50kg of musk, 7.50kg of shelled and deoiled wood turtle seeds, 7.50kg of made Aconitum aconiti, 7.50kg of maple gum, 3.74kg of made frankincense, 3.74kg of made myrrh, 7.50kg of Wulingzhi fried with vinegar, 7.50kg of earthworm, wine Stir-fried angelica 3.74kg, fragrant ink 0.60kg, 95% ethanol 400ml, starch 3.26kg, purified water 14.0kg;

[0027] B, powder the nine Chinese herbal medicines other than musk, and sieve;

[0028] c. Preparation of adhesive: Weigh 2kg of purified water, pour it into a clean stainless steel mixing bucket, add 1.74kg of starch and stir continuously, pour 12kg of boiled purified water into the mixing bucket and stir to become translucent;

[0029] d. Mixing soft material: Add the remaining 1.52kg starch and 40kg powder into the trough mixer, turn on the mixer and mix for 10 minutes...

experiment example 2

[0033] Experimental Example 2 Quality Standard and Inspection Method of Capsules of the present invention

[0034] 1. Properties: capsules of the present invention. The appearance should be clean and tidy, without bonding, deformation or cracking, and there should be no peculiar smell. The content is yellow-brown powder; the gas is fragrant and the taste is slightly bitter.

[0035] 2. Identification:

[0036] 2.1 Identification 1: Take this product, grind it finely, and observe it under a microscope: the stone cells are rectangular or square-like, with slightly thicker walls. Cotyledon cells are rectangular or polygonal, containing paste powder grains and fat oil lumps. The parenchyma cells are spindle-shaped, with slightly thicker walls and very fine oblique staggered textures. The amorphous mass is light yellowish brown, embedded with small square crystals. The muscle fibers are layered, colorless, yellowish or light brown, wave-like curved, and sometimes vertically st...

Embodiment 1

[0142] The preparation method of embodiment 1 capsule of the present invention:

[0143] a, take the following Chinese medicinal materials as raw materials:

[0144] 6.76g of musk, 33.8g of shelled and oiled beetle seeds, 33.8g of aconitum, 33.8g of sweetgum, 16.85g of frankincense, 16.85g of myrrh, 33.8g of Wulingzhi fried with vinegar, 33.8g of earthworm, wine Stir-fried angelica 16.85g, fragrant ink 2.7g;

[0145] B, powder the nine Chinese herbal medicines other than musk, and sieve;

[0146] c, take 5%~6.4% starch of total drug content, wherein 50% is made into starch paste;

[0147] d. Mix 80% of the fine powder obtained in step b with the remaining starch in step c, add the starch paste obtained in step c to make soft materials and granules, and the drying temperature is 45°C;

[0148]e. Add 95% ethanol to the musk and the remaining medicinal powder, mix, make soft materials, make granules, dry, and the temperature is 28°C;

[0149] f. Mix the granules obtained in s...

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Abstract

An anti-inflammatory, antalgic and anticancer capsule is prepared from muskone and 9 Chinese-medicinal materials including wild aconite root, myrrh, earthworm, Chinese angelica root, etc through granulating, and ordinary-temp drying.

Description

technical field [0001] The invention provides an anti-inflammatory, analgesic and anti-cancer capsule and a preparation method thereof, belonging to the field of traditional Chinese medicine. Background technique [0002] In the prior art, "Xiaojin Pills" belongs to the variety recorded in the 1995 edition of "Chinese Pharmacopoeia", and is a modified formulation of "Xiaojin Pills". It is made from myrrh, Wulingzhi fried with vinegar, earthworm, angelica fried with wine, and fragrant ink. It was first recorded in Qing Dynasty. Ruyan, Hengyan, sticky gangrene and other diseases." It is widely used clinically, and later generations of doctors often use it to treat various surgical diseases and achieve good results. Now doctors have accumulated rich experience in using Xiaojindan to treat surgical diseases, and have developed its basic functions and indications. The pills made from the original prescription of Xiaojindan are included in the "Chinese Pha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K31/122A61K35/55A61P29/00A61P35/00
Inventor 陈辉明刘晓亮李可引
Owner 四川省天基生物药业有限公司
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