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Traditional Chinese medicine extract for treating respiratory diseases, preparation method and use thereof

The technology of extract and respiratory tract is applied in the field of pharmaceutical preparations containing the traditional Chinese medicine extract and its preparation, which can solve the problems affecting children's physical and mental health, study and life, etc., achieves good controllability and stability, and is convenient to carry and take. , the effect of high bioavailability

Inactive Publication Date: 2018-12-07
TIANJIN INSTITUTE OF PHARMA RESEARCH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Children's chronic cough can not be cured for a long time, which seriously affects children's physical and mental health and study life, and brings additional economic burden to parents and society

Method used

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  • Traditional Chinese medicine extract for treating respiratory diseases, preparation method and use thereof
  • Traditional Chinese medicine extract for treating respiratory diseases, preparation method and use thereof
  • Traditional Chinese medicine extract for treating respiratory diseases, preparation method and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Take the bulk drug according to the following ratio: (note: each part is 100g)

[0058] 10 parts of Nansha Ginseng, 10 parts of Sage Grass, 1 part of Coltsfoot Flower, 10 parts of Ophiopogon japonicus

[0059] 6 parts bellflower, 10 parts trichosanthes, 1 part licorice

[0060] (1) For the above Qiwei raw materials, add water with an amount 12 times the total weight of the medicinal materials, heat and reflux extract 3 times, each time for 1 hour, combine the extracts, filter, and concentrate the filtrate to a relative density of 1.05, then add 95% v / v ethanol until the alcohol content is 70% v / v, place, filter, the filtrate is decompressed to recover the solvent, concentrated, dried, pulverized to obtain 850g of the Chinese medicine extract of the present invention, and set aside;

[0061] (2) Get above-mentioned Chinese medicine extract 232g, cross 80 mesh sieves, add 220g dextrin, 48g powdered sugar, granulate, pack, obtain the pharmaceutical granule of the present...

Embodiment 2

[0063] Take the bulk drug according to the following ratio: (note: each part is 100g)

[0064] 5 parts of Nansha Ginseng, 5 parts of Sage Grass, 10 parts of Coltsfoot Flower, 5 parts of Ophiopogon japonicus

[0065] 1 part bellflower, 1 part trichosanthum, 3 parts licorice

[0066] Step (1) is the same as in Example 1, and step (2) adds 180 g of starch and 110 g of dextrin to the Chinese medicine extract obtained in (1), mixes evenly, makes granules, dries, and then prepares capsules according to a conventional process.

Embodiment 3

[0068] Take the bulk drug according to the following ratio: (note: each part is 100g)

[0069] 1 part of Nansha Ginseng, 2 parts of Sage Grass, 5 parts of Coltsfoot Flower, 1 part of Ophiopogon japonicus

[0070] 3 parts bellflower, 5 parts trichosanthum, 6 parts licorice

[0071] (1) For the above Qiwei raw materials, add 50% v / v ethanol whose weight is 10 times the total weight of the medicinal materials, reflux extraction 3 times, each time for 1 hour, combine the extracts, filter, the filtrate is decompressed to recover the solvent, concentrate, and dry , pulverize, get Chinese medicine extract 450g of the present invention, for subsequent use;

[0072] (2) Get above-mentioned Chinese medicine extract 235g, cross 80 mesh sieves, add 265g starch, granulate, dry, tabletting, obtain pharmaceutical tablet of the present invention.

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PUM

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Abstract

The invention provides a traditional Chinese medicine extract for treating respiratory diseases. The traditional Chinese medicine extract comprises the following raw materials in parts by weight: 1 to10 parts of adenophora tetraphylla, 1 to 10 parts of gnaphalium affine, 1 to 10 parts of flos farfarae, 1 to 10 parts of ophiopogon japonicus, 1 to 6 parts of platycodon grandiflorum, 1 to 10 parts of radices trichosanthis and 1 to 6 parts of licorice. The invention also provides a preparation method of the traditional Chinese medicine extract and use thereof, and a pharmaceutical preparation containing the traditional Chinese medicine extract and a preparation method thereof. The traditional Chinese medicine extract of the invention has the effects of clearing away heat and relieving exterior syndrome, relieving cough and removing phlegm, has significant anti-inflammatory, antibacterial and anti-viral effects, and has the effect of treating both respiratory diseases and cough caused by respiratory diseases, and especially children with chronic cough. The pharmaceutical preparation of the invention has the characteristics of convenient carrying, high bioavailability, and good controllability and stability.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine extract for treating respiratory diseases, a preparation method and application thereof, and a pharmaceutical preparation containing the traditional Chinese medicine extract and a preparation method thereof. Background technique [0002] Respiratory system disease is the disease with the highest incidence rate in pediatrics, accounting for more than 70% of the total number of pediatric diseases. Cough is the most common symptom of pediatric respiratory diseases, which belongs to the category of disease names in pediatric lung system diseases and syndromes of traditional Chinese medicine. Clinically, the causes of cough are complex. Acute respiratory disease (ARI) is the main cause of cough, accounting for the highest incidence of childhood diseases worldwide, and it is also an important factor of pediatric death. Whether at home or abroad,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P11/00A61P11/14
CPCA61K36/28A61K36/342A61K36/346A61K36/428A61K36/484A61K36/8968A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 廖茂梁郑雅楠孙卫
Owner TIANJIN INSTITUTE OF PHARMA RESEARCH
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