Pogostemon cablin freeze-dried powder and preparation method thereof

A technology of freeze-dried powder and extract, which is applied in pharmaceutical formulas, cosmetic preparations, dressing preparations, etc. It can solve the problems of uneven product quality, short storage time, allergic redness, etc., and achieve long shelf life and good antibacterial properties , Excellent heat resistance and cold resistance effect

Inactive Publication Date: 2020-02-04
广州市迪笙生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Freeze-dried powder preparations can better retain the active substances in the extract of S. chinensis by freeze-drying technology; at present, there is no method for retaining the active substances in the extract of S. chinensis by freeze-drying technology; With the progress of the times, people pay more and more attention to their skin quality. However, due to the uneven quality of products on the market, some people use inferior products, resulting in allergic redness. However, traditional skin care products have the problem of short shelf life, so it is necessary to A kind of lyophilized powder suitable for anti-redness and desensitization solves the above problems

Method used

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  • Pogostemon cablin freeze-dried powder and preparation method thereof
  • Pogostemon cablin freeze-dried powder and preparation method thereof
  • Pogostemon cablin freeze-dried powder and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0025] The preparation method of the left-handed lyophilized powder provided by the present embodiment comprises the following steps:

[0026] (1) Wash the fresh leaves of A. chinensis and put them into the juice extractor according to the weight ratio of 1:3 with autoclaved sterile water. After squeezing the juice with the juicer, filter it with a 300-mesh filter cloth to obtain the left-handed Fragrant crude extract;

[0027] (2) Weigh the following raw materials by weight percentage: 94% of the crude extract of P. chinensis, 5% of 1,3-butanediol, 1% of the first preservative, and combine 1,3-butanediol and the first preservative agent pre-mixed to obtain a clear mixed solution, the resulting mixed solution was added to the crude extract of S. chinensis and stirred evenly, after being filtered by a membrane separation ultrafiltration machine, the second preservative was added and stirred evenly to obtain the extract of S. chinensis, wherein, The addition amount of the secon...

Embodiment 2

[0034] The preparation method of the left-handed lyophilized powder provided by the present embodiment comprises the following steps:

[0035] (1) Put the fresh leaves of A. chinensis into the juicer according to the weight ratio of 1:10 with the autoclaved aseptic water after washing. After squeezing the juice with the juicer, filter it with a 500-mesh filter cloth to obtain the left-handed Fragrant crude extract;

[0036] (2) Weigh the following raw materials by weight percentage: 98.9% of the crude extract of S. chinensis, 1% of 1,3-butanediol, 0.1% of the first preservative, and mix 1,3-butanediol and the first preservative agent pre-mixed to obtain a clear mixed solution, the resulting mixed solution was added to the crude extract of S. chinensis and stirred evenly, after being filtered by a membrane separation ultrafiltration machine, the second preservative was added and stirred evenly to obtain the extract of S. chinensis, wherein, The addition amount of the second pr...

Embodiment 3

[0041] (1) Wash the fresh leaves of C. chinensis and put them into the juicer according to the weight ratio of 1:1 with autoclaved sterile water. After squeezing the juice with the juicer, filter it with a 100-mesh filter cloth to obtain the left-handed Fragrant crude extract;

[0042] (2) Weigh the following raw materials in percentage by weight: 88% of the crude extract of P. agent pre-mixed to obtain a clear mixed solution, the resulting mixed solution was added to the crude extract of S. chinensis and stirred evenly, after being filtered by a membrane separation ultrafiltration machine, the second preservative was added and stirred evenly to obtain the extract of S. chinensis, wherein, The added amount of the second preservative is 0.1% of the extract of S. chinensis;

[0043](3) Weigh the following raw materials by weight percentage: 10% of mannitol, 0.1% of trehalose, 0.1% of pullulan, 5% of S. chinensis extract, 0.1% of small molecule hyaluronic acid, and the balance o...

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Abstract

The invention discloses a pogostemon cablin freeze-dried powder and a preparation method thereof. The pogostemon cablin freeze-dried powder is prepared from the following raw materials in percentage by weight: 2-10% of mannitol, 0.1-2% of trehalose, 0.1-1% of pullulan polysaccharide, 1-15% of a pogostemon cablin extracting solution, 0.01-0.1% of hyaluronic acid and the balance of water. The freeze-dried powder can retain active ingredients in pogostemon cablin. The freeze-dried powder has significant anti-inflammatory, anti-redness-swelling, antibacterial, astringent, wound repair and anti-oxidant effects, and has excellent heat resistance and cold resistance, has good antibacterial properties against bacteria such as molds and yeasts, and is long in shelf life.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a freeze-dried powder of Zuo Shouxiang and a preparation method thereof. Background technique [0002] Aiming at the current skin disease (hormone face) caused by the frequent use of inferior cosmetics or hormonal drugs, the method and technology of the combination of left-handed incense extract + freeze-dried powder; left-handed incense is rich in monoterpenes (Monotepenes ), sesquiterpenes (Sequiterpenes), flavonoids (Flavonoids), phenols (Phenols) (such as carvacrol (Carvacrol) and thymol (Thymol), etc.) Antibacterial, astringent, wound repairing and antioxidant properties. Freeze-dried powder is obtained by freezing the water in the extract in advance by using the vacuum freeze-drying method of a freeze dryer, and then sublimating the frozen water in the extract in a sterile vacuum environment to obtain freeze-drying. In short, the water in the extract is extracted in a l...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/60A61K8/73A61K8/34A61K36/53A61Q19/08A61Q19/00A61Q17/00A61P17/02A61P29/00A61P31/04A61P31/10
CPCA61K8/9789A61K8/735A61K8/73A61K8/60A61K8/345A61K36/53A61Q19/00A61Q17/005A61Q19/08A61P17/02A61P29/00A61P31/10A61P31/04A61K2800/84
Inventor 陈舒敏
Owner 广州市迪笙生物科技有限公司
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