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Composition containing resveratrol and soybean isoflavone and its preparation and use

A technology of soybean isoflavone and resveratrol, which is applied in the preparation of organic compounds, chemical instruments and methods, organic chemistry and other directions, can solve problems such as side effects, application limitations, tumor occurrence, etc., and achieve the effect of simple process

Active Publication Date: 2005-10-12
西安天行健天然生物制品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the anti-oxidant substances are used at home and abroad to delay aging, such as vitamin C, E and some other plant preparations; but there are some shortcomings: such as ineffective effects, poor stability, and certain side effects
Although synthetic estrogen can effectively treat menopausal syndrome, it has the risk of causing tumors, so its application is greatly limited

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0255] Contains 15%-20% resveratrol extract 140-220g

[0256] Containing 20%-35% soybean isoflavone extract 60-120g

[0257] (1), the preparation method of described containing resveratrol extract is as follows:

[0258] Rinse the grape seeds and skin with pure water, extract three times with 70% ethanol at 60°C, each time for 2 hours, filter the alcohol extract, then recover the ethanol, concentrate the extract, pass the concentrate through silica gel column chromatography, and wash with the eluent Deconcentrate at 60-70°C for more than 30 minutes to Baume degree 15, and at a temperature ≥180°C, instant sterilize, spray dry, put the finished extract into a sterile bag, set aside, the extract Contains 15%-20% resveratrol.

[0259] (2), the preparation method of described soybean isoflavone-containing extract is as follows:

[0260] Rinse the soybean germ or soybean meal with pure water, extract three times with 70% ethanol at 60°C, each time for 2 hours, filter the alcohol ...

specific Embodiment 2

[0265] Contains 17% resveratrol extract 180g

[0266] Contains 30% Soybean Isoflavone Extract 90g

[0267] (1), the preparation method of described containing resveratrol extract is as follows:

[0268] The roots of Polygonum cuspidatum were crushed, extracted three times with 80% ethanol at 60°C, 2 hours each time, the alcohol extract was filtered, then the ethanol was recovered, and the extract was concentrated. The concentrated solution was hydrolyzed with sulfuric acid for 5 hours, washed 3 times with water, filtered, the filtrate was eluted and crystallized by the eluent, and dried in vacuum. % resveratrol.

[0269] (2), the preparation method of described soybean isoflavone-containing extract is as follows:

[0270] Rinse the soybean germ or soybean meal with pure water, extract three times with 70% ethanol at 60°C, each time for 2 hours, filter the alcohol extract, recover the ethanol, concentrate the extract, crystallize with 80% acetone, and dissolve the crystal wi...

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PUM

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Abstract

A composition containing resveratrol and soya isoflavone, its production and used are disclosed. It is carried out by extracting extractive of resveratrol from grape seed, grape skin or Polygonum cuspidatum, and extracting extractive of soya isoflavone from soya germ and bean dreg. Its advantages include no risk of tumour, to delay senility and to add skeletal density.

Description

1. Technical field: [0001] The invention relates to a composition containing resveratrol and soybean isoflavone, a preparation method and application thereof. 2. Technical background: [0002] Studies have found that the generation of oxygen free radicals in the body is one of the important factors in the development of aging, so effective removal of oxygen free radicals produced in the body is very important in anti-aging. At present, substances with antioxidant effects are mostly used at home and abroad to delay aging, such as vitamin C, E and some other plant preparations; but there are some shortcomings: such as ineffective effects, poor stability, and certain side effects. [0003] In terms of osteoporosis in middle-aged and elderly women, traditional calcium supplementation alone has no obvious effect, because the osteoporosis of this group is mainly due to the gradual decrease in the level of estrogen secreted by the ovary, and estrogen controls the calcium on the bon...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07C37/70C07C39/21C07D311/36
Inventor 汪云
Owner 西安天行健天然生物制品有限公司
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