Kekang drip pill used for treating cougha nd asthma and its preparation method

A technology of Kang dripping pills and medicines, which is applied in the field of oral preparations of pharmaceutical compositions, can solve the problems of first-pass bioavailability of liver and intestines, unfavorable to improve the ability of patients to seek medical treatment, physical harm to staff, etc. Bioavailability, environmentally friendly effect

Inactive Publication Date: 2005-10-26
北京博智绿洲医药科技有限公司
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Problems solved by technology

[0009] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation proce

Method used

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Embodiment Construction

[0029] Now with several groups of specific examples, the preparation method of Kekang dripping pills of the present invention will be further described.

[0030] [Group 1: Trials with a single substrate]

[0031] 1. Raw materials: According to [Preparation Method 1], the dry extract powder containing 4 active ingredients of traditional Chinese medicines, such as Chlorophytum Chlorophytum, Iron-clad Gold, Goat’s Milk Leaf, and Gynostemma Pentaphyllum, is prepared for use;

[0032] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0033] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0034] 4. According to the process given in [Preparation Method] 4-7, Kekang Dropping Pills of different specifications can be obta...

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Abstract

A Chinese medicine in the form of dripping pill for treating cough and asthma is prepared from 4 Chinese-medicinal materials including lysionotus herb, lineate supplejack root, gynostemma pentaphyllum, etc. Its preparing process is also disclosed.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has the functions of relieving cough and reducing phlegm, moistening lung and relieving asthma, and is used for the treatment of diseases such as cough and asthma caused by wind-heat. A kind of pharmaceutical composition oral preparation prepared from four traditional Chinese medicines as raw materials. Background technique [0002] Kekang buccal tablets prepared according to the preparation method given in the national drug standard WS-10503 (ZD-0503)-2002, is a kind of medicine that has the functions of relieving cough and reducing phlegm, moistening lung and relieving asthma, and is used for the treatment of wind-heat caused by wind-heat. The chemical-containing tablets for the treatment of cough, asthma and other diseases have been clinically verified and have definite curative effects. They are commonly used medicines for clinical and family treatment of the above diseases. [0...

Claims

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Application Information

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Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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